Development Level

Tbio 24 | 11,445
Tchem 10 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

increased lean body mass 4 | 172
abnormal embryo size 3 | 220
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal pericardium morpholog... 1 | 26
abnormal rib morphology 1 | 10
abnormal skin coloration 1 | 25
brachydactyly 1 | 19
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
embryonic growth retardation 1 | 106
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased total body fat amoun... 1 | 134
pallor 1 | 34
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
syndactyly 1 | 23
vertebral fusion 1 | 23

Disease

Carcinoma 24 | 11,493
osteosarcoma 22 | 7,950
ovarian cancer 20 | 8,520
psoriasis 20 | 6,694
medulloblastoma, large-cell 19 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
glioblastoma 15 | 5,792
lung cancer 15 | 4,740
malignant mesothelioma 15 | 3,232
ependymoma 13 | 4,679
lung adenocarcinoma 13 | 2,716
Breast cancer 12 | 3,578
non-small cell lung cancer 12 | 2,890
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Cancer 9 | 2,499
group 3 medulloblastoma 9 | 4,104
tuberculosis 9 | 2,010
adrenocortical carcinoma 8 | 1,428
astrocytic glioma 8 | 2,597
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
primitive neuroectodermal tumor 8 | 3,035
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
breast carcinoma 7 | 1,638
subependymal giant cell astrocytoma 7 | 2,287
Pick disease 6 | 1,894
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
Endometriosis 5 | 540
colon cancer 5 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
spina bifida 5 | 1,074
Atopic dermatitis 4 | 952
Down syndrome 4 | 499
Multiple myeloma 4 | 1,332
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
cystic fibrosis 4 | 1,696
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Bipolar Disorder 3 | 666
Byzanthine arch palate 3 | 194
Cleft Palate 3 | 271
Curvature of spine 3 | 282
Gaucher disease type 1 3 | 180
Hypoplastic mandible condyle 3 | 275
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Muscle hypotonia 3 | 571
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Short stature 3 | 531
Strabismus 3 | 270
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
lung carcinoma 3 | 2,843
pediatric high grade glioma 3 | 1,064
Big calvaria 2 | 147
Blepharoptosis 2 | 231
Epilepsy 2 | 792
Hypoglycemia 2 | 152
Impaired cognition 2 | 96
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Leukemia 2 | 104
Lymphedema 2 | 42
Male infertility 2 | 206
Melanoma 2 | 711
Mental impairment 2 | 95
Myopathy 2 | 185
Myopia 2 | 176
Neurodevelopmental Disorders 2 | 70
Neuropathy 2 | 261
Parkinson's disease 2 | 392
Pectus excavatum 2 | 100
Polycystic kidney disease 1 2 | 21
Seizures 2 | 596
Skin cancer 2 | 469
astrocytoma 2 | 1,146
hereditary spastic paraplegia 2 | 318
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Cardiovascular System 35 | 15,192
Respiratory system 35 | 16,393

Target Family

Enzyme 34 | 4,145
Non-IDG 2 | 12,091

GO Function

phosphoprotein phosphatase act... 36 | 36
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113
Dual specificity protein phosphatase 9 DUSP9 Tbio Enzyme -1.15238 17.2 202
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
CTD small phosphatase-like protein 2 CTDSPL2 Tdark Enzyme -0.57403 3.70 102
Glycerol-3-phosphate phosphatase PGP Tbio Enzyme -1.48294 30.0 90
Phospholipid phosphatase 2 PLPP2 Tbio Enzyme -1.34465 21.0 105
Dual specificity protein phosphatase 16 DUSP16 Tbio Enzyme -1.32944 22.4 159
Protein phosphatase 1H PPM1H Tbio Enzyme -0.96074 10.7 113
Disks large-associated protein 5 DLGAP5 Tbio Non-IDG -1.61614 44.1 180
Pyridoxal phosphate phosphatase PDXP Tbio Enzyme -2.37320 235.7 79