Development Level

Tbio 23 | 10,625
Tchem 12 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

increased lean body mass 3 | 107
preweaning lethality, complete... 3 | 633
abnormal bone structure 2 | 131
decreased body weight 2 | 174
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
abnormal behavior 1 | 226
abnormal coat-hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal retinal outer nuclear... 1 | 5
abnormal rib morphology 1 | 28
cardiovascular system phenotyp... 1 | 35
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating magnesiu... 1 | 11
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased caudal vertebrae num... 1 | 8
increased grip strength 1 | 83
increased heart weight 1 | 37
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
vertebral fusion 1 | 23

Disease

osteosarcoma 21 | 7,933
psoriasis 21 | 6,685
ovarian cancer 19 | 8,491
medulloblastoma, large-cell 18 | 6,234
lung cancer 16 | 4,473
malignant mesothelioma 15 | 3,163
glioblastoma 14 | 5,572
lung adenocarcinoma 13 | 2,714
atypical teratoid / rhabdoid tumor 12 | 4,369
non-small cell lung cancer 12 | 2,798
Breast cancer 11 | 3,098
Cancer 10 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
invasive ductal carcinoma 9 | 2,950
pediatric high grade glioma 9 | 2,712
adrenocortical carcinoma 8 | 1,427
ependymoma 8 | 2,514
oligodendroglioma 8 | 2,849
primitive neuroectodermal tumor 8 | 3,031
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 1,563
ulcerative colitis 8 | 2,087
astrocytic glioma 7 | 2,241
group 4 medulloblastoma 7 | 1,875
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
pancreatic cancer 7 | 2,300
pilocytic astrocytoma 7 | 3,086
breast carcinoma 6 | 1,614
ductal carcinoma in situ 6 | 1,745
pituitary cancer 6 | 1,972
sonic hedgehog group medulloblastoma 6 | 1,482
Down syndrome 5 | 548
Endometriosis 5 | 535
Pick disease 5 | 1,893
colon cancer 5 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Atopic dermatitis 4 | 944
Carcinoma 4 | 2,147
Multiple myeloma 4 | 1,327
active Crohn's disease 4 | 918
acute quadriplegic myopathy 4 | 1,157
cystic fibrosis 4 | 1,670
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
posterior fossa group A ependymoma 4 | 1,511
spina bifida 4 | 1,064
Alzheimer's disease 3 | 644
Gaucher disease type 1 3 | 171
IGA Glomerulonephritis 3 | 454
Rheumatoid Arthritis 3 | 1,170
Waldenstrons macroglobulinemia 3 | 764
active ulcerative colitis 3 | 477
adult high grade glioma 3 | 2,148
aldosterone-producing adenoma 3 | 664
astrocytoma 3 | 1,493
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
group 3 medulloblastoma 3 | 2,254
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
primary pancreatic ductal adenocarcinoma 3 | 1,271
tuberculosis and treatment for 6 months 3 | 686
Asthma 2 | 349
Crohn's disease 2 | 304
LEOPARD Syndrome 2 | 20
Leukemia 2 | 88
Neuropathy 2 | 210
Parkinson's disease 2 | 364
Schizophrenia 2 | 503
acute myeloid leukemia 2 | 785
atypical teratoid/rhabdoid tumor 2 | 1,095
cutaneous lupus erythematosus 2 | 1,056
diabetes mellitus 2 | 1,663
hereditary spastic paraplegia 2 | 313
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
ovarian neoplasm 2 | 97
primary Sjogren syndrome 2 | 788
Adenocarcinoma 1 | 115
Beta thalassemia 1 | 19
Celiac disease 1 | 112
Colon Carcinoma 1 | 25
Congenital heart disease 1 | 63
DOID:2627 1 | 14
Developmental Disabilities 1 | 20
Drug psychosis 1 | 7
Endometrial cancer 1 | 32
Glioma 1 | 66
Juvenile Myelomonocytic Leukemia 1 | 21
Kidney cancer 1 | 121
Language Development Disorders 1 | 9
Malignant tumor of prostate 1 | 26
Meningioma 1 | 27
Motor Skills Disorders 1 | 6
Mucoepidermoid carcinoma 1 | 19
Neoplasm Invasiveness 1 | 127
Pulmonary valve stenosis 1 | 10
Sezary Syndrome 1 | 26
Squamous cell carcinoma of the head and neck 1 | 24
cartilage-hair hypoplasia 1 | 7

Tissue

Blood and immune system 36 | 17,994
Cardiovascular System 36 | 17,957
Digestive Tract 36 | 18,472
Endocrine System 36 | 18,511
Female tissues 36 | 18,646
Liver and Pancreas 36 | 18,135
Male tissues 36 | 17,968
Nervous System 36 | 18,560
Respiratory system 36 | 17,483
Skin and soft tissues 36 | 18,114
Urinary Tract 36 | 18,443

Target Family

Enzyme 34 | 4,146
Non-IDG 2 | 11,969

GO Function

phosphoprotein phosphatase act... 36 | 36
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 16 DUSP16 Tbio Enzyme -1.25169 21.5 128
Phospholipid phosphatase 2 PLPP2 Tbio Enzyme -1.33905 20.8 93
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.42592 25.0 106
Protein phosphatase 1H PPM1H Tbio Enzyme -0.96031 10.6 89
Dual specificity protein phosphatase 10 DUSP10 Tbio Enzyme -1.46941 35.9 248
Dual specificity protein phosphatase CDC14A CDC14A Tbio Enzyme -2.30298 210.2 218
M-phase inducer phosphatase 1 CDC25A Tchem Enzyme -2.45436 266.0 1243
M-phase inducer phosphatase 2 CDC25B Tchem Enzyme -2.31154 209.2 666
M-phase inducer phosphatase 3 CDC25C Tchem Enzyme -2.51338 295.3 723
Phospholipid phosphatase 3 PLPP3 Tbio Enzyme -1.75974 61.0 81