Development Level

Tbio 6 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

abnormal bone structure 1 | 187
decreased bone mineral content 1 | 151

Disease

glioblastoma 6 | 5,792
ependymoma 5 | 4,679
subependymal giant cell astrocytoma 5 | 2,287
Astrocytoma, Pilocytic 4 | 3,081
atypical teratoid / rhabdoid tumor 4 | 5,112
lung carcinoma 4 | 2,843
ovarian cancer 4 | 8,520
Cancer 3 | 2,499
Carcinoma 3 | 11,493
Liver Cirrhosis, Experimental 3 | 769
adult high grade glioma 3 | 3,801
lung cancer 3 | 4,740
Alzheimer's disease 2 | 658
Antiphospholipid syndrome 2 | 19
Atherosclerosis 2 | 291
Chronic obstructive pulmonary disease 2 | 184
Duchenne muscular dystrophy 2 | 601
Eye disease 2 | 62
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Lipid metabolism disorder 2 | 114
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
inflammatory breast cancer 2 | 286
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
Adenocarcinoma of lung 1 | 142
Allergic hypersensitivity disease 1 | 126
Allergic rhinitis 1 | 94
Anemia 1 | 365
Animal Mammary Neoplasms 1 | 136
Arthritis 1 | 290
Barrett's esophagus 1 | 182
Carcinoma, Hepatocellular 1 | 228
Carcinoma, Renal Cell 1 | 124
Carcinoma, Squamous Cell 1 | 110
Cardiovascular system disease 1 | 246
Coronary artery disease 1 | 268
Delusions 1 | 11
Dementia 1 | 175
Down syndrome 1 | 499
Hallucinations, Visual 1 | 6
Heart disease 1 | 306
Heart failure 1 | 162
Hypobetalipoproteinemias 1 | 5
Kidney disease 1 | 430
Lewy Body Disease 1 | 21
Liver carcinoma 1 | 240
Liver neoplasms 1 | 130
Low density lipoprotein decreased 1 | 5
Lupus erythematosus 1 | 57
Macular degeneration 1 | 65
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mouth Neoplasms 1 | 55
Multiple system atrophy 1 | 29
Neoplasm Metastasis 1 | 168
Neurodegenerative disease 1 | 414
Parkinson's disease 1 | 392
Parkinsonian Disorders 1 | 56
Pick disease 1 | 1,894
Pre-Eclampsia 1 | 68
Prostatic Neoplasms 1 | 495
Renal Cell Carcinoma 1 | 214
Schizophrenia 1 | 1,160
Squamous cell carcinoma 1 | 129
Stomach Neoplasms 1 | 300
Toxic encephalopathy 1 | 141
Type 2 diabetes mellitus 1 | 272
Weight Gain 1 | 100
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
acute myeloid leukemia 1 | 783
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
dermatomyositis 1 | 966
gastric carcinoma 1 | 807
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
lung adenocarcinoma 1 | 2,716
nasopharyngeal carcinoma 1 | 1,058
nephrosclerosis 1 | 333
pediatric high grade glioma 1 | 1,064
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Liver and Pancreas 6 | 16,750
Nervous System 6 | 16,725
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192
Female tissues 5 | 17,400
Male tissues 5 | 17,142
Respiratory system 4 | 16,393

Target Family

Non-IDG 7 | 12,091
Enzyme 1 | 4,145

GO Function

phospholipase inhibitor activi... 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein PINLYP Tdark Enzyme 1.00 0.07 3
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
Putative annexin A2-like protein ANXA2P2 Tdark Non-IDG -2.68290 825.4 0
Beta-synuclein SNCB Tbio Non-IDG -2.05833 98.5 287
Angiopoietin-related protein 3 ANGPTL3 Tbio Non-IDG -2.00286 113.5 396
Phosducin PDC Tbio Non-IDG -2.36871 242.5 78
Annexin A4 ANXA4 Tbio Non-IDG -2.18594 153.6 316
Annexin A5 ANXA5 Tbio Non-IDG -3.91162 6864.1 552