Development Level

Tbio 6 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

abnormal lens morphology 1 | 81
cataract 1 | 92
decreased circulating iron lev... 1 | 32
decreased total body fat amoun... 1 | 207
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating iron lev... 1 | 30
increased lean body mass 1 | 172

Disease

Carcinoma 9 | 11,493
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
medulloblastoma, large-cell 5 | 6,241
Atherosclerosis 4 | 291
Coronary artery disease 4 | 268
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Lipid metabolism disorder 3 | 114
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic lateral sclerosis 2 | 451
Asphyxiating thoracic dystrophy 2 | 44
Barth syndrome 2 | 23
Cardiovascular system disease 2 | 246
Eruptive xanthoma 2 | 3
Hypercholesterolemia, Familial 2 | 23
Hyperlipidemia 2 | 43
Hyperlipidemias 2 | 17
Hyperlipoproteinemia Type II 2 | 12
Kidney cancer 2 | 2,613
Metabolic syndrome X 2 | 52
Neurodegenerative disease 2 | 414
Obesity 2 | 678
Paraplegia 2 | 74
Sengers syndrome 2 | 18
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
hereditary spastic paraplegia 2 | 318
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
mucosa-associated lymphoid tissue lymphoma 2 | 484
oligodendroglioma 2 | 2,850
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Acquired metabolic disease 1 | 336
Alopecia 1 | 115
Angina Pectoris 1 | 32
Animal Mammary Neoplasms 1 | 136
Axonal neuropathy 1 | 27
Babinski Reflex 1 | 100
Barrett's esophagus 1 | 182
Cardiomyopathies 1 | 110
Dysarthria 1 | 192
Gastric leiomyoma 1 | 3
Hepatitis C 1 | 94
Hyperinsulinism 1 | 133
Hyperreflexia 1 | 209
Hypoplasia of corpus callosum 1 | 90
Hypotrichosis 1 | 47
Hypotrichosis 13 1 | 2
Hypotrichosis 6 1 | 4
Hypotrichosis 7 1 | 4
Hypotrichosis 8 1 | 6
Hypotrichosis simplex 1 | 7
Ichthyosis vulgaris 1 | 11
Icterus 1 | 82
Liver Cirrhosis, Experimental 1 | 769
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Melanoma 1 | 711
Monilethrix 1 | 18
Monoparesis - leg 1 | 27
Myocardial Infarction 1 | 151
Necrosis 1 | 53
Peeling skin syndrome 1 | 17
Periventricular white matter abnormalities 1 | 8
Progressive disorder 1 | 142
Spastic Paraplegia 1 | 42
Telecanthus 1 | 62
Total Hypotrichosis, Mari type 1 | 1
Toxic encephalopathy 1 | 141
Vomiting 1 | 116
Weakness of lower limb 1 | 27
Woolly hair, autosomal dominant 1 | 5
Woolly hair, congenital 1 | 5
Wooly hair 1 | 17

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Respiratory system 9 | 16,393
Cardiovascular System 8 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 1 | 12,091

GO Function

phospholipase activity 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelial lipase LIPG Tchem Enzyme -2.28530 192.2 712
Lipoprotein lipase LPL Tchem Enzyme -3.09646 876.3 338
Hepatic triacylglycerol lipase LIPC Tchem Enzyme -2.56840 389.0 258
SEC23-interacting protein SEC23IP Tbio Non-IDG -0.85882 6.77 143
Monoacylglycerol lipase ABHD6 ABHD6 Tchem Enzyme -1.37418 26.1 71
Lipase member I LIPI Tbio Enzyme -1.79886 59.9 71
Group 10 secretory phospholipase A2 PLA2G10 Tchem Enzyme -2.41226 298.2 57
Phospholipase DDHD2 DDHD2 Tbio Enzyme -1.23833 16.6 49
Lipase member H LIPH Tbio Enzyme -1.36582 22.3 43
Phospholipase DDHD1 DDHD1 Tbio Enzyme -1.23443 15.3 31