Development Level

Tbio 12 | 11,445
Tchem 12 | 1,598
Tdark 6 | 6,588

IMPC Phenotype

cataract 2 | 92
decreased leukocyte cell numbe... 2 | 73
abnormal lens morphology 1 | 81
decreased cardiac muscle contr... 1 | 11
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
dilated heart left ventricle 1 | 11
increased body weight 1 | 25
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased mean platelet volume 1 | 45
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 15 | 11,493
psoriasis 13 | 6,694
ovarian cancer 12 | 8,520
lung cancer 11 | 4,740
osteosarcoma 11 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
lung adenocarcinoma 9 | 2,716
medulloblastoma, large-cell 9 | 6,241
Breast cancer 7 | 3,578
glioblastoma 7 | 5,792
interstitial cystitis 7 | 2,312
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
Schizophrenia 6 | 1,160
adult high grade glioma 6 | 3,801
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
active Crohn's disease 5 | 922
adrenocortical carcinoma 5 | 1,428
diabetes mellitus 5 | 1,728
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Toxic encephalopathy 4 | 141
acute quadriplegic myopathy 4 | 1,158
group 4 medulloblastoma 4 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Arthritis 3 | 290
Atherosclerosis 3 | 291
Cancer 3 | 2,499
Coronary artery disease 3 | 268
Epilepsy 3 | 792
Ileocolitis 3 | 5
Muscle hypotonia 3 | 571
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Acute pancreatitis 2 | 10
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Cerebellar Dysmetria 2 | 56
Cerebral atrophy 2 | 178
Cognitive delay 2 | 608
Depressive disorder 2 | 409
Down syndrome 2 | 499
Dull intelligence 2 | 645
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Frontal bossing 2 | 157
Gas gangrene 2 | 17
Global developmental delay 2 | 608
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Lissencephaly 2 | 69
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
MAJOR AFFECTIVE DISORDER 2 2 | 22
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Muscle Spasticity 2 | 195
Neurodegeneration with brain iron accumulation 2 | 20
Pick disease 2 | 1,894
Poland syndrome 2 | 14
Poor school performance 2 | 645
Progressive disorder 2 | 142
Seizures 2 | 596
Short nose 2 | 132
Small nose 2 | 132
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
hepatocellular carcinoma 2 | 547
limb girdle muscular dystrophy 2A 2 | 213
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
Abnormal vision 1 | 52
Nephrotic Syndrome 1 | 78
Nonorganic psychosis 1 | 84

Tissue

Digestive Tract 29 | 17,369
Blood and immune system 28 | 16,909
Skin and soft tissues 28 | 17,230
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Urinary Tract 27 | 16,678
Male tissues 26 | 17,142
Respiratory system 26 | 16,393
Liver and Pancreas 25 | 16,750
Nervous System 24 | 16,725
Cardiovascular System 23 | 15,192

Target Family

Enzyme 25 | 4,145
Non-IDG 5 | 12,091

GO Function

phospholipase A2 activity 30 | 30
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Post-GPI attachment to proteins factor 6 TMEM8A Tdark Non-IDG -0.56820 3.55 16
Retinoic acid receptor responder protein 3 RARRES3 Tbio Non-IDG -1.84020 71.0 164
Cytosolic phospholipase A2 delta PLA2G4D Tbio Enzyme -0.54284 3.41 45
Cytosolic phospholipase A2 gamma PLA2G4C Tchem Enzyme -1.27690 20.9 63
Phospholipase ABHD3 ABHD3 Tbio Enzyme -0.41218 2.23 91
Group IIE secretory phospholipase A2 PLA2G2E Tchem Enzyme -0.44734 2.04 30
Protein PROCA1 PROCA1 Tbio Non-IDG -0.54042 3.33 57
Calcium-independent phospholipase A2-gamma PNPLA8 Tbio Enzyme -1.96549 89.5 114
Cytosolic phospholipase A2 epsilon PLA2G4E Tdark Enzyme -0.25773 2.16 47
Group IIF secretory phospholipase A2 PLA2G2F Tchem Enzyme -0.17609 1.39 2