Development Level

Tbio 34 | 11,445
Tchem 6 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased vertical activity 3 | 208
enlarged heart 3 | 210
decreased leukocyte cell numbe... 2 | 73
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pupil morphology 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased circulating insulin ... 1 | 76
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38

Disease

Carcinoma 31 | 11,493
ovarian cancer 25 | 8,520
psoriasis 24 | 6,694
glioblastoma 19 | 5,792
ependymoma 15 | 4,679
medulloblastoma, large-cell 15 | 6,241
osteosarcoma 15 | 7,950
adult high grade glioma 14 | 3,801
atypical teratoid / rhabdoid tumor 14 | 5,112
lung carcinoma 14 | 2,843
group 3 medulloblastoma 13 | 4,104
lung cancer 13 | 4,740
Astrocytoma, Pilocytic 12 | 3,081
Breast cancer 12 | 3,578
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
malignant mesothelioma 11 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
invasive ductal carcinoma 10 | 2,951
oligodendroglioma 10 | 2,850
astrocytic glioma 9 | 2,597
pancreatic cancer 9 | 2,398
Kidney cancer 8 | 2,613
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Cancer 6 | 2,499
colon cancer 6 | 1,478
diabetes mellitus 6 | 1,728
nasopharyngeal carcinoma 6 | 1,058
primary pancreatic ductal adenocarcinoma 6 | 1,109
Melanoma 5 | 711
Vascular disease 5 | 319
astrocytoma 5 | 1,146
ductal carcinoma in situ 5 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Duchenne muscular dystrophy 4 | 601
Pick disease 4 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
lung adenocarcinoma 4 | 2,716
Alcoholic Intoxication, Chronic 3 | 289
Autosomal recessive predisposition 3 | 1,442
Down syndrome 3 | 499
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
juvenile dermatomyositis 3 | 1,187
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
Allergic hypersensitivity disease 2 | 126
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Atherosclerosis 2 | 291
Attention deficit hyperactivity disorder 2 | 278
Breast Neoplasms 2 | 445
Congenital hypoplasia of penis 2 | 176
Electroretinogram abnormal 2 | 95
Epilepsy 2 | 792
Glaucoma 2 | 239
Kidney disease 2 | 430
Lens Opacities 2 | 231
Lipid metabolism disorder 2 | 114
Mammary Neoplasms 2 | 425
Mental Depression 2 | 333
Myocardial Infarction 2 | 151
Neoplasm Invasiveness 2 | 161
Parkinson's disease 2 | 392
Reperfusion Injury 2 | 86
Retinal Degeneration 2 | 106
Stomach Neoplasms 2 | 300
Systemic lupus erythematosus 2 | 194
Type 2 diabetes mellitus 2 | 272
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical adenoma 2 | 131
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 288
fibroadenoma 2 | 559
head and neck cancer 2 | 271
hepatocellular carcinoma 2 | 547
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333
pediatric high grade glioma 2 | 1,064
sarcoidosis 2 | 370

Tissue

Endocrine System 40 | 18,159
Nervous System 40 | 16,725
Digestive Tract 39 | 17,369
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Respiratory system 37 | 16,393
Blood and immune system 36 | 16,909
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 34 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Function

phosphatidylserine binding 40 | 40
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 ASAP1 Tbio Non-IDG -1.76454 62.6 183
Copine-1 CPNE1 Tbio Non-IDG -1.04880 11.6 151
Caveolae-associated protein 2 CAVIN2 Tbio Non-IDG -2.85477 685.4 84
Junctophilin-2 JPH2 Tbio Non-IDG -2.21890 163.0 229
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Copine-6 CPNE6 Tbio Non-IDG -0.79740 6.43 129
Oxysterol-binding protein-related protein 10 OSBPL10 Tbio Non-IDG -0.69897 6.13 127
Adseverin SCIN Tbio Non-IDG -1.90989 89.8 72
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 PLCD1 Tchem Enzyme -2.17969 140.9 120