Development Level

Tbio 23 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
anophthalmia 1 | 33
cataract 1 | 92
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
impaired pupillary reflex 1 | 26
increased cardiac stroke volum... 1 | 1
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 16 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
adrenocortical carcinoma 6 | 1,428
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Kidney cancer 5 | 2,613
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Cancer 4 | 2,499
Rheumatoid arthritis 4 | 1,191
adult high grade glioma 4 | 3,801
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
tuberculosis 4 | 2,010
Arthritis 3 | 290
Bipolar Disorder 3 | 666
Prostatic Neoplasms 3 | 495
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Anemia 2 | 365
Arthritis, Rheumatoid 2 | 174
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Autosomal recessive predisposition 2 | 1,442
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Chronic Lymphocytic Leukemia 2 | 262
Curvature of spine 2 | 282
Disease Models, Animal 2 | 155
Hypercholesterolemia 2 | 44
Infantile onset 2 | 238
Inguinal hernia 2 | 14
Kidney disease 2 | 430
Lens Opacities 2 | 231
Liver Cirrhosis, Experimental 2 | 769
Melanoma 2 | 711
Muscular atrophy 2 | 71
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Splenomegaly 2 | 190
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
Absence of B cells 1 | 4
Absent B cells 1 | 4
Combined Cellular And Humoral Immune Defects With Granulomas 1 | 2
Combined immunodeficiency with skin granulomas 1 | 2
Conjunctival hamartoma 1 | 7
Cowden disease 1 | 18
Desquamation of skin soon after birth 1 | 10
Diffusely thickened skin 1 | 20
Fibrous skin tumor of tuberous sclerosis 1 | 18
Gastrointestinal hamartomatous polyps 1 | 10
Hamartoma Syndrome, Multiple 1 | 10
Hamartomatous polyp 1 | 10
Hypercholesterolemia, Familial 1 | 23
Hyperkeratosis, generalized 1 | 14
Low B cell count 1 | 8
Macule 1 | 19
Metaplasia 1 | 5
Multiple, subcutaneous nodules 1 | 53
Polyp of large intestine 1 | 8
Reflex, Abnormal 1 | 5
Reticuloendotheliosis, familial, with eosinophilia 1 | 3
Severe T lymphocytopenia 1 | 4
Small thymus 1 | 13
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
T-Lymphocytopenia 1 | 9
Thyroid Gland Follicular Adenoma 1 | 9

Tissue

Blood and immune system 24 | 16,909
Endocrine System 24 | 18,159
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Urinary Tract 23 | 16,678
Digestive Tract 22 | 17,369
Female tissues 22 | 17,400
Skin and soft tissues 22 | 17,230
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 22 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634

GO Function

phosphatidylinositol-3,4-bisph... 24 | 24
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
Pleckstrin homology-like domain family A member 3 PHLDA3 Tbio Non-IDG -0.83900 8.89 101
WASH complex subunit 2C WASHC2C Tbio Non-IDG -0.83634 0.00000 45
Pleckstrin-2 PLEK2 Tbio Non-IDG -1.09971 14.3 40
SEC14 domain and spectrin repeat-containing protein 1 SESTD1 Tbio Non-IDG -0.75718 5.72 91
Retinoschisin RS1 Tbio Non-IDG -2.10828 131.3 39
Alpha-tocopherol transfer protein TTPA Tbio Non-IDG -2.38323 247.5 79
GRB2-associated-binding protein 2 GAB2 Tbio Non-IDG -2.08460 139.8 494
Unconventional myosin-Ig MYO1G Tbio Non-IDG -1.98465 98.3 35
Huntingtin-interacting protein 1 HIP1 Tbio Non-IDG -1.73638 55.9 202