Development Level

Tbio 32 | 10,625
Tchem 2 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal retina morphology 2 | 100
decreased lean body mass 2 | 195
embryonic lethality prior to t... 2 | 187
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal optic disc morphology 1 | 10
corneal opacity 1 | 25
decreased Ly6C low monocyte nu... 1 | 23
decreased body weight 1 | 174
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased spleen weight 1 | 13
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
embryonic lethality prior to o... 1 | 148
fused cornea and lens 1 | 4
fused phalanges 1 | 1
impaired pupillary reflex 1 | 14
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased Ly6C high monocyte n... 1 | 12
increased cardiac stroke volum... 1 | 1
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 23 | 8,492
osteosarcoma 22 | 7,933
psoriasis 15 | 6,685
non-small cell lung cancer 13 | 2,798
Carcinoma 12 | 2,147
medulloblastoma, large-cell 12 | 6,234
glioblastoma 11 | 5,572
Breast cancer 10 | 3,099
lung adenocarcinoma 10 | 2,714
lung cancer 10 | 4,473
atypical teratoid / rhabdoid tumor 9 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
pediatric high grade glioma 9 | 2,712
primitive neuroectodermal tumor 9 | 3,031
ulcerative colitis 9 | 2,087
invasive ductal carcinoma 8 | 2,950
malignant mesothelioma 8 | 3,163
oligodendroglioma 8 | 2,849
subependymal giant cell astrocytoma 8 | 2,287
Cancer 7 | 2,346
diabetes mellitus 7 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
lung carcinoma 7 | 2,844
pancreatic cancer 7 | 2,300
colon cancer 6 | 1,475
cystic fibrosis 6 | 1,670
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,299
primary Sjogren syndrome 6 | 789
tuberculosis 6 | 1,563
Alzheimer's disease 5 | 644
astrocytoma 5 | 1,493
medulloblastoma 5 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,271
sonic hedgehog group medulloblastoma 5 | 1,482
Pick disease 4 | 1,893
ependymoma 4 | 2,514
pilocytic astrocytoma 4 | 3,086
spina bifida 4 | 1,064
Atopic dermatitis 3 | 944
IGA Glomerulonephritis 3 | 454
Polycystic Ovary Syndrome 3 | 335
Weight Gain 3 | 87
acute myeloid leukemia 3 | 785
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
breast carcinoma 3 | 1,614
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 967
posterior fossa group A ependymoma 3 | 1,511
progressive supranuclear palsy 3 | 674
Acute Promyelocytic Leukemia 2 | 32
Bladder Neoplasm 2 | 109
Cardiomyopathies 2 | 90
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Hyperglycemia 2 | 120
Liver carcinoma 2 | 217
Mental depression 2 | 58
Multiple myeloma 2 | 1,328
Obesity 2 | 616
Parkinson's disease 2 | 364
Rheumatoid Arthritis 2 | 1,171
Schizophrenia 2 | 503
chronic lymphocytic leukemia 2 | 244
chronic lymphosyte leukemia 2 | 232
cystic fibrosis and chronic rhinosinusitis 2 | 213
fibroadenoma 2 | 557
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 550
interstitial lung disease 2 | 292
juvenile dermatomyositis 2 | 1,189
mucosa-associated lymphoid tissue lymphoma 2 | 480
periodontitis 2 | 269
Amebiasis 1 | 22
Arthritis, Experimental 1 | 39
Cardiomegaly 1 | 66
Cardiomyopathy, Hypertrophic, Familial 1 | 21
Colon Carcinoma 1 | 25
Cone dystrophy 1 | 59
Diabetic Retinopathy 1 | 53
Familial adenomatous polyposis 1 | 33
Fundus dystrophy 1 | 77
Leukocyte adhesion deficiency 1 | 15
Loiasis 1 | 6
Macular degeneration 1 | 44
Meningioma 1 | 27
Myasthenia Gravis 1 | 26
Sickle Cell Anemia 1 | 54
Skin disease 1 | 65
Smallpox 1 | 20
Strongyloidiasis 1 | 9
Tuberculosis, Pulmonary 1 | 3
Wilson disease 1 | 16
pulmonary tuberculosis 1 | 8

Tissue

Blood and immune system 36 | 17,995
Endocrine System 36 | 18,512
Female tissues 36 | 18,647
Liver and Pancreas 36 | 18,136
Male tissues 36 | 17,969
Nervous System 36 | 18,561
Urinary Tract 36 | 18,444
Cardiovascular System 35 | 17,958
Digestive Tract 35 | 18,473
Respiratory system 35 | 17,484
Skin and soft tissues 34 | 18,115

Target Family

Non-IDG 28 | 11,969
Enzyme 5 | 4,146
Kinase 2 | 634
Epigenetic 1 | 242

GO Function

phosphatidylinositol-3,4,5-tri... 36 | 36
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rho GTPase-activating protein 9 ARHGAP9 Tbio Enzyme -1.72520 53.3 32
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.97819 13.6 86
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.94183 13.6 61
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 ASAP1 Tbio Non-IDG -1.72865 60.7 170
Pleckstrin homology-like domain family A member 3 PHLDA3 Tbio Non-IDG -0.80473 6.44 84
Junctophilin-2 JPH2 Tbio Non-IDG -2.18771 149.5 168
V(D)J recombination-activating protein 2 RAG2 Tbio Epigenetic -2.92849 764.3 183
Unconventional myosin-X MYO10 Tbio Non-IDG -1.45944 32.9 38
WASH complex subunit FAM21C WASHC2C Tbio Non-IDG -0.78960 0.00000 43
Ras GTPase-activating-like protein IQGAP2 IQGAP2 Tbio Enzyme -1.37198 24.1 118