Development Level

Tbio 33 | 11,651
Tchem 2 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

decreased caudal vertebrae num... 3 | 53
preweaning lethality, complete... 3 | 979
abnormal retina morphology 2 | 71
embryonic lethality prior to t... 2 | 278
impaired pupillary reflex 2 | 26
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hypoactivity 1 | 132
increased CD4-positive, alpha ... 1 | 4
increased cardiac stroke volum... 1 | 1
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 26 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 23 | 7,950
psoriasis 15 | 6,694
Kidney cancer 13 | 2,613
medulloblastoma, large-cell 13 | 6,241
Breast cancer 12 | 3,578
non-small cell lung cancer 12 | 2,890
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
atypical teratoid / rhabdoid tumor 9 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
ependymoma 8 | 4,679
group 3 medulloblastoma 8 | 4,104
invasive ductal carcinoma 8 | 2,951
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
ulcerative colitis 8 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung carcinoma 7 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Cancer 6 | 2,499
adult high grade glioma 6 | 3,801
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
colon cancer 5 | 1,478
pediatric high grade glioma 5 | 1,064
primary Sjogren syndrome 5 | 735
Alzheimer's disease 4 | 658
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Chronic Lymphocytic Leukemia 4 | 262
Pick disease 4 | 1,894
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
spina bifida 4 | 1,074
Arthritis 3 | 290
Atopic dermatitis 3 | 952
Endometrial cancer 3 | 311
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Mental Depression 3 | 333
Parkinson's disease 3 | 392
Polycystic ovary syndrome 3 | 360
Schizophrenia 3 | 1,160
Weight Gain 3 | 100
cutaneous lupus erythematosus 3 | 1,057
progressive supranuclear palsy 3 | 676
Anemia 2 | 365
Bladder Neoplasm 2 | 112
Carcinoma, Hepatocellular 2 | 228
Congenital deafness 2 | 185
Deafness 2 | 198
Diarrhea 2 | 253
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Failure to gain weight 2 | 365
Fever 2 | 138
Hearing Loss, Partial 2 | 185
Hepatomegaly 2 | 285
Hyperglycemia 2 | 137
Hypothyroidism 2 | 122
Increased susceptibility to bacterial infections 2 | 42
Infantile onset 2 | 238
Liver carcinoma 2 | 240
Melanoma 2 | 711
Meningitis 2 | 67
Multiple myeloma 2 | 1,332
Otitis Media 2 | 52
Pediatric failure to thrive 2 | 365
Pneumonia 2 | 174
Prone to bacterial infection 2 | 42
Prostatic Neoplasms 2 | 495
Recurrent bacterial infection 2 | 42
Rheumatoid arthritis 2 | 1,191
Urinary Bladder Neoplasms 2 | 114
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
cystic fibrosis and chronic rhinosinusitis 2 | 214
fibroadenoma 2 | 559
hearing impairment 2 | 199
hepatocellular carcinoma 2 | 547
interstitial lung disease 2 | 298
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
periodontitis 2 | 293
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Endocrine System 37 | 18,159
Blood and immune system 36 | 16,909
Liver and Pancreas 36 | 16,750
Nervous System 36 | 16,725
Digestive Tract 35 | 17,369
Female tissues 35 | 17,400
Male tissues 35 | 17,142
Respiratory system 35 | 16,393
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 5 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242

GO Function

phosphatidylinositol-3,4,5-tri... 37 | 37
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide DAPP1 Tbio Non-IDG -1.14626 21.0 307
V(D)J recombination-activating protein 2 RAG2 Tbio Epigenetic -2.94111 784.2 194
Zinc finger FYVE domain-containing protein 1 ZFYVE1 Tbio Non-IDG -2.09354 121.0 113
Huntingtin-interacting protein 1-related protein HIP1R Tbio Non-IDG -1.52916 38.6 195
Tyrosine-protein kinase BTK BTK Tclin Kinase -3.07545 1199.5 810
Rac GTPase-activating protein 1 RACGAP1 Tbio Enzyme -1.69445 57.6 382
Fermitin family homolog 2 FERMT2 Tbio Non-IDG -1.88943 85.7 180
Annexin A8 ANXA8L1 Tbio Non-IDG -1.21683 15.6 112
Neurogranin NRGN Tbio Non-IDG -2.45065 289.7 114
Pleckstrin homology domain-containing family B member 2 PLEKHB2 Tbio Non-IDG -1.07339 9.89 42