Development Level

Tbio 14 | 11,445
Tclin 8 | 613
Tchem 5 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal gait 2 | 69
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal pancreas morphology 1 | 13
abnormal vocalization 1 | 21
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased erythrocyte cell num... 1 | 39
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123

Disease

Carcinoma 22 | 11,493
glioblastoma 17 | 5,792
psoriasis 15 | 6,694
adult high grade glioma 14 | 3,801
lung cancer 14 | 4,740
ependymoma 13 | 4,679
osteosarcoma 13 | 7,950
Astrocytoma, Pilocytic 12 | 3,081
ovarian cancer 12 | 8,520
atypical teratoid / rhabdoid tumor 11 | 5,112
medulloblastoma, large-cell 11 | 6,241
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
Cancer 9 | 2,499
interstitial cystitis 9 | 2,312
subependymal giant cell astrocytoma 9 | 2,287
astrocytic glioma 8 | 2,597
invasive ductal carcinoma 8 | 2,951
Kidney cancer 7 | 2,613
Melanoma 7 | 711
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
Breast cancer 6 | 3,578
Schizophrenia 6 | 1,160
Skin cancer 6 | 469
colon cancer 6 | 1,478
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
primitive neuroectodermal tumor 5 | 3,035
Bipolar Disorder 4 | 666
Epilepsy 4 | 792
Kidney disease 4 | 430
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Allergic rhinitis 3 | 94
Asthma 3 | 385
Biliary dyskinesia 3 | 7
Chronic gastritis 3 | 5
Chronic obstructive lung disease 3 | 6
Endometriosis 3 | 540
Excessive salivation 3 | 5
Gastric ulcer 3 | 33
General anesthesia 3 | 53
Liver cancer 3 | 604
Major Depressive Disorder 3 | 301
Multiple Sclerosis 3 | 540
Nephrolithiasis 3 | 56
Osteoporosis 3 | 363
Peptic Ulcer 3 | 27
Unipolar Depression 3 | 250
Urinary Incontinence 3 | 50
Vagal Reflex Bradycardia 3 | 5
active Crohn's disease 3 | 922
mucosa-associated lymphoid tissue lymphoma 3 | 484
Arthritis 2 | 290
Atherosclerosis 2 | 291
Cocaine-Related Disorders 2 | 92
Constipation 2 | 181
Dermatitis, Atopic 2 | 37
Down syndrome 2 | 499
Dyschezia 2 | 135
Dysuria 2 | 26
Essential Hypertension 2 | 94
Gastrointestinal Radiography Adjunct 2 | 11
Heart disease 2 | 306
Hyperalgesia 2 | 83
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Large intestine cancer 2 | 126
Liver Cirrhosis, Experimental 2 | 769
Lung disease 2 | 142
Malaria 2 | 160
Pain agnosia 2 | 104
Parkinson's disease 2 | 392
Seizures 2 | 596
Urinary Tract Irritation 2 | 24
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
cystic fibrosis and chronic rhinosinusitis 2 | 214
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hepatocellular carcinoma 2 | 547
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Skin and soft tissues 27 | 17,230
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Urinary Tract 26 | 16,678
Respiratory system 25 | 16,393
Blood and immune system 24 | 16,909
Cardiovascular System 23 | 15,192

Target Family

Enzyme 16 | 4,145
GPCR 10 | 408
Non-IDG 1 | 12,091

GO Function

phosphatidylinositol phospholi... 27 | 27
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..