Development Level

Tbio 45 | 10,625
Tdark 17 | 7,003
Tchem 10 | 1,890
Tclin 2 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal embryo size 3 | 112
increased circulating alkaline... 3 | 119
increased or absent threshold ... 3 | 128
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased circulating potassiu... 2 | 17
decreased fasted circulating g... 2 | 49
embryonic lethality prior to t... 2 | 187
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal spinal cord morpholog... 1 | 8
abnormal vertebrae morphology 1 | 14
absent heartbeat 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased follicular B cell nu... 1 | 4
decreased lean body mass 1 | 195
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
dilated heart left ventricle 1 | 10
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased body weight 1 | 42
increased circulating aspartat... 1 | 17
increased circulating phosphat... 1 | 24
increased hematocrit 1 | 36
increased mean corpuscular hem... 1 | 93
increased neutrophil cell numb... 1 | 15
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
microphthalmia 1 | 15
prolonged PQ interval 1 | 3
small epididymis 1 | 3

Disease

ovarian cancer 44 | 8,484
medulloblastoma, large-cell 35 | 6,234
osteosarcoma 32 | 7,933
glioblastoma 30 | 5,572
psoriasis 28 | 6,685
atypical teratoid / rhabdoid tumor 23 | 4,369
Breast cancer 18 | 3,094
pilocytic astrocytoma 15 | 3,086
Carcinoma 14 | 2,147
lung cancer 14 | 4,466
lung carcinoma 14 | 2,844
pediatric high grade glioma 14 | 2,712
pituitary cancer 14 | 1,972
diabetes mellitus 13 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
group 4 medulloblastoma 12 | 1,875
invasive ductal carcinoma 12 | 2,950
tuberculosis 12 | 1,557
ulcerative colitis 12 | 2,087
Pick disease 11 | 1,893
astrocytic glioma 11 | 2,241
ependymoma 11 | 2,514
malignant mesothelioma 11 | 3,162
pancreatic cancer 11 | 2,300
subependymal giant cell astrocytoma 11 | 2,287
oligodendroglioma 10 | 2,849
adult high grade glioma 9 | 2,148
juvenile dermatomyositis 9 | 1,189
primary pancreatic ductal adenocarcinoma 9 | 1,271
primitive neuroectodermal tumor 9 | 3,031
interstitial cystitis 8 | 2,299
non-small cell lung cancer 8 | 2,798
progressive supranuclear palsy 8 | 674
Cancer 7 | 2,346
group 3 medulloblastoma 7 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
Obesity 6 | 616
acute quadriplegic myopathy 6 | 1,157
cystic fibrosis 6 | 1,665
lung adenocarcinoma 6 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group B ependymoma 6 | 1,530
sonic hedgehog group medulloblastoma 6 | 1,482
Neurodegenerative disease 5 | 383
Rheumatoid Arthritis 5 | 1,160
adrenocortical carcinoma 5 | 1,427
breast carcinoma 5 | 1,614
ductal carcinoma in situ 5 | 1,745
spina bifida 5 | 1,064
Atherosclerosis 4 | 275
Schizophrenia 4 | 501
aldosterone-producing adenoma 4 | 664
atypical teratoid/rhabdoid tumor 4 | 1,095
colon cancer 4 | 1,475
gastric carcinoma 4 | 832
medulloblastoma 4 | 1,524
posterior fossa group A ependymoma 4 | 1,511
tuberculosis and treatment for 3 months 4 | 327
tuberculosis and treatment for 6 months 4 | 686
Arthritis 3 | 248
Cardiomegaly 3 | 66
Chronic Lymphocytic Leukemia 3 | 242
Intellectual disability 3 | 573
Multiple myeloma 3 | 1,327
Neuropathy 3 | 210
Prostatic Neoplasms 3 | 471
Retinitis pigmentosa 3 | 153
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 780
cutaneous lupus erythematosus 3 | 1,056
primary Sjogren syndrome 3 | 789
Amyotrophic Lateral Sclerosis 2 | 431
Autistic Disorder 2 | 320
Autosomal dominant cerebellar ataxia 2 | 34
Brachydactyly 2 | 52
Centronuclear myopathy 2 | 21
Cerebellar Ataxia 2 | 72
Down syndrome 2 | 548
Essential Hypertension 2 | 82
Hypertension 2 | 287
Hypertensive disease 2 | 193
IGA Glomerulonephritis 2 | 454
Kidney disease 2 | 396
Lupus Erythematosus, Systemic 2 | 73
Myocardial Infarction 2 | 126
Myopathy 2 | 128
Respiratory failure 2 | 30
Retinal Degeneration 2 | 49
Sensenbrenner syndrome 2 | 15
active Crohn's disease 2 | 918
astrocytoma 2 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cystic fibrosis and chronic rhinosinusitis 2 | 213
dermatomyositis 2 | 933
esophageal adenocarcinoma 2 | 737
mucosa-associated lymphoid tissue lymphoma 2 | 480
non primary Sjogren syndrome sicca 2 | 840
sarcoidosis 2 | 358
systemic lupus erythematosus 2 | 156

Tissue

Blood and immune system 72 | 17,995
Endocrine System 72 | 18,512
Liver and Pancreas 72 | 18,136
Nervous System 72 | 18,561
Digestive Tract 71 | 18,473
Female tissues 71 | 18,647
Male tissues 71 | 17,969
Urinary Tract 71 | 18,444
Cardiovascular System 70 | 17,958
Respiratory system 70 | 17,484
Skin and soft tissues 70 | 18,115

Target Family

Non-IDG 49 | 11,971
Kinase 8 | 634
Enzyme 6 | 4,146
Ion Channel 4 | 341
Transcription Factor 4 | 1,400
Epigenetic 3 | 242

GO Function

phosphatidylinositol binding 74 | 74
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger CCHC domain-containing protein 14 ZCCHC14 Tdark Non-IDG 0.29 1.53 54
Guanine nucleotide exchange factor DBS MCF2L Tbio Non-IDG -0.93602 11.4 104
Tubby protein homolog TUB Tbio Transcription Factor -2.38823 263.8 53
Septin-12 SEPT12 Tbio Non-IDG -1.27742 20.7 89
Huntingtin-interacting protein 1-related protein HIP1R Tbio Non-IDG -1.51948 37.8 178
Inhibitor of growth protein 2 ING2 Tbio Epigenetic -1.47891 33.6 155
PX domain-containing protein 1 PXDC1 Tdark Non-IDG 0.00000 30
Ribosomal protein S6 kinase delta-1 RPS6KC1 Tdark Kinase -0.14760 1.41 80
PAS domain-containing serine/threonine-protein kinase PASK Tbio Kinase -0.98152 11.2 95
Sorting nexin-32 SNX32 Tdark Non-IDG 1.08 0.07 75