Development Level

Tbio 9 | 11,445

IMPC Phenotype

abnormal epididymis morphology 1 | 42
abnormal skin morphology 1 | 50
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased lactate dehydrogenas... 1 | 16
enlarged spleen 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
glioblastoma 6 | 5,792
ovarian cancer 6 | 8,520
astrocytic glioma 5 | 2,597
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
Cancer 4 | 2,499
ependymoma 4 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
acute quadriplegic myopathy 3 | 1,158
atypical teratoid / rhabdoid tumor 3 | 5,112
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
medulloblastoma, large-cell 3 | 6,241
pediatric high grade glioma 3 | 1,064
Breast cancer 2 | 3,578
Chronic Lymphocytic Leukemia 2 | 262
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
Abnormal helices 1 | 11
Abnormality of the lymphatic system 1 | 14
Acquired cubitus valgus 1 | 18
Birthmark 1 | 35
Cafe au lait spots, multiple 1 | 17
Cafe-au-Lait Spots 1 | 37
Carcinoma, Renal Cell 1 | 124
Cardiovascular Abnormalities 1 | 31
Connective tissue cancer 1 | 10
Decreased projection of midface 1 | 105
Defective enamel matrix 1 | 35
Deglutition Disorders 1 | 132
Dental Enamel Hypoplasia 1 | 43
Diabetes Mellitus, Experimental 1 | 108
Dyslipidemias 1 | 27
Dysplasia of tooth enamel 1 | 35
Fetal overgrowth 1 | 16
Fibrosarcoma 1 | 14
Freckles 1 | 33
Generalized overgrowth 1 | 16
Glioma 1 | 74
Hemangioma 1 | 69
Hypertriglyceridemia 1 | 17
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Insulin Resistance 1 | 72
Juvenile Myelomonocytic Leukemia 1 | 21
LEOPARD syndrome 1 | 20
Learning disability 1 | 17
Leber congenital amaurosis 1 1 | 6
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Leukemia, Myelomonocytic, Juvenile 1 | 20
Liposarcoma 1 | 20
Liver Neoplasms, Experimental 1 | 59
Low posterior hairline 1 | 52
Lymphatic Diseases 1 | 14
Lymphoid leukemia 1 | 160
Malar flattening 1 | 129
Malignant peripheral nerve sheath tumor 1 | 12
Mammary Neoplasms, Animal 1 | 136
Midface retrusion 1 | 105
Mild Mental Retardation 1 | 70
Neurilemmoma 1 | 23
Neurofibroma 1 | 8
Neurofibromatosis 1 | 40
Neurofibrosarcoma 1 | 7
Noonan syndrome 1 | 34
Ostium secundum atrial septal defect 1 | 9
Overgrowth 1 | 16
Persistent generalized lymphadenopathy 1 | 15
Phaeochromocytoma 1 | 20
Pheochromocytoma 1 | 24
Precancerous Conditions 1 | 80
Pulmonary Stenosis 1 | 45
Relative macrocephaly 1 | 12
Renal Cell Carcinoma 1 | 214
Rhabdomyosarcoma 1 | 39
Sarcoma 1 | 62
Scoliosis 1 | 44
Small midface 1 | 105
Thin dental enamel 1 | 35
fascioscapulohumeral muscular dystrophy 1 | 100

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 1 | 4,145

GO Function

phosphatidylethanolamine bindi... 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Phosphatidylethanolamine N-methyltransferase PEMT Tbio Enzyme -1.90213 89.9 149
Phosphatidylethanolamine-binding protein 1 PEBP1 Tbio Non-IDG -2.62467 484.3 511
CMRF35-like molecule 8 CD300A Tbio Non-IDG -1.58380 41.3 219
Annexin A11 ANXA11 Tbio Non-IDG -1.68299 54.0 203
Lactadherin MFGE8 Tbio Non-IDG -2.72398 560.9 392
Extended synaptotagmin-2 ESYT2 Tbio Non-IDG -1.20659 15.4 56
Microtubule-associated proteins 1A/1B light chain 3A MAP1LC3A Tbio Non-IDG -2.18414 134.1 944
Phospholipid transfer protein PLTP Tbio Non-IDG -2.53404 383.2 232