Development Level

Tbio 10 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

abnormal vocalization 1 | 21
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
ovarian cancer 6 | 8,520
atypical teratoid / rhabdoid tumor 5 | 5,112
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
Lipodystrophy 3 | 40
Pick disease 3 | 1,894
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
posterior fossa group B ependymoma 3 | 416
primary pancreatic ductal adenocarcinoma 3 | 1,109
Atopic dermatitis 2 | 952
Down syndrome 2 | 499
Fever 2 | 138
Myalgia 2 | 54
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
dermatomyositis 2 | 966
lung adenocarcinoma 2 | 2,716
nephrosclerosis 2 | 333
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Acne 1 | 52
Acute kidney injury 1 | 70
Amyotrophic lateral sclerosis 1 | 451
Arthralgia 1 | 90
Becker muscular dystrophy 1 | 191
Bone pain 1 | 42
Cachexia 1 | 50
Cardiovascular system disease 1 | 246
Congenital dyserythropoietic anemia 1 | 18
Congenital hemolytic anemia 1 | 32
Coronary artery disease 1 | 268
Creatine phosphokinase serum increased 1 | 110
Decreased tendon reflex 1 | 122
Dental caries 1 | 164
Disease Progression 1 | 136
Duchenne muscular dystrophy 1 | 601
Edema 1 | 81
Elevated creatine kinase 1 | 110
Failure to gain weight 1 | 365
Fatty liver disease 1 | 103
Gaucher disease type 1 1 | 180
Globe disease 1 | 67
Headache 1 | 37
Hepatomegaly 1 | 285
Hyperkalemia 1 | 17
Liver Cirrhosis, Experimental 1 | 769
Lung squamous cell carcinoma 1 | 10
Muscle Weakness 1 | 170
Myoglobinuria 1 | 15
Osteomyelitis 1 | 42
Parkinson's disease 1 | 392
Pediatric failure to thrive 1 | 365
Pseudohypoparathyroidism 1 | 18
Reflex, Deep Tendon, Absent 1 | 92
Seizures 1 | 596
Sengers syndrome 1 | 18
Stomach Neoplasms 1 | 300
Type 2 diabetes mellitus 1 | 272
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
atypical teratoid/rhabdoid tumor 1 | 357
gastric carcinoma 1 | 807
hereditary spastic paraplegia 1 | 318
interstitial lung disease 1 | 298
limb girdle muscular dystrophy 2A 1 | 213
mucosa-associated lymphoid tissue lymphoma 1 | 484
pediatric high grade glioma 1 | 1,064
permanent atrial fibrillation 1 | 45
pituitary cancer 1 | 1,972
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010

Tissue

Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Blood and immune system 11 | 16,909
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192
Skin and soft tissues 10 | 17,230

Target Family

Enzyme 13 | 4,145

GO Function

phosphatidate phosphatase acti... 13 | 13
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phospholipid phosphatase 5 PLPP5 Tbio Enzyme -0.73719 6.23 78
Phospholipid phosphatase 2 PLPP2 Tbio Enzyme -1.34465 21.0 105
Phosphatidate phosphatase LPIN2 LPIN2 Tbio Enzyme -1.50639 30.9 152
Phospholipid phosphatase 3 PLPP3 Tbio Enzyme -1.77858 65.1 94
Phospholipid phosphatase-related protein type 4 PLPPR4 Tbio Enzyme -1.15591 13.7 92
Phospholipid phosphatase-related protein type 5 PLPPR5 Tdark Enzyme -0.07918 1.14 87
Phospholipid phosphatase-related protein type 3 PLPPR3 Tbio Enzyme -1.11680 11.9 86
Phosphatidate phosphatase LPIN1 LPIN1 Tbio Enzyme -2.13963 149.5 280
Phospholipid phosphatase-related protein type 2 PLPPR2 Tdark Enzyme 0.30 0.58 56
Phosphatidate phosphatase LPIN3 LPIN3 Tbio Enzyme -1.43940 24.6 88