Development Level

Tbio 23 | 11,445
Tchem 8 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating glucose ... 2 | 126
decreased lean body mass 2 | 135
decreased total retina thickne... 2 | 17
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal humerus morphology 1 | 11
abnormal locomotor behavior 1 | 24
abnormal testis morphology 1 | 43
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased cornea thickness 1 | 2
decreased mean corpuscular hem... 1 | 50
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 18 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 14 | 7,950
psoriasis 12 | 6,694
ependymoma 11 | 4,679
lung cancer 11 | 4,740
glioblastoma 10 | 5,792
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
interstitial cystitis 7 | 2,312
primitive neuroectodermal tumor 7 | 3,035
tuberculosis 7 | 2,010
Cancer 6 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
inflammatory breast cancer 5 | 286
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Multiple myeloma 4 | 1,332
adult high grade glioma 4 | 3,801
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Chronic Lymphocytic Leukemia 3 | 262
Liver Cirrhosis, Experimental 3 | 769
Pick disease 3 | 1,894
Vaccinia 3 | 36
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
mucosa-associated lymphoid tissue lymphoma 3 | 484
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Acquired metabolic disease 2 | 336
Arthritis, Juvenile 2 | 126
Atrial Fibrillation 2 | 124
COPD 2 | 118
Chronic heart failure 2 | 46
Crohn's disease 2 | 321
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Epilepsy 2 | 792
Glaucoma 2 | 239
Hypertension 2 | 396
Hypertensive disease 2 | 292
Juvenile arthritis 2 | 126
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
Proteinuria 2 | 144
Rheumatoid arthritis 2 | 1,191
Systemic lupus erythematosus 2 | 194
X-linked dystonia-parkinsonism 2 | 9
acute myeloid leukemia 2 | 783
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
sonic hedgehog group medulloblastoma 2 | 467
type II diabetes mellitus and post-ischemic heart failure 2 | 88
urothelial carcinoma 2 | 318
Adrenal cortical adenocarcinoma 1 | 4
Adrenal gland cancer 1 | 12
Anti-nuclear factor positive 1 | 18
Apraxias 1 | 27
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Choroid Plexus Papilloma 1 | 10
Chronic Obstructive Airway Disease 1 | 37
Coughing 1 | 25
Edema 1 | 81
Gastrointestinal stromal tumor 1 | 62
Hematuria 1 | 36
Hemoptysis 1 | 6
Myocardial Reperfusion Injury 1 | 37
Ophthalmoparesis 1 | 11
Pneumoconiosis 1 | 15
Renal glomerular disease 1 | 12
Sinusitis 1 | 65
Temporal arteritis 1 | 2
Type 1 diabetes mellitus 1 | 109
progressive myoclonus epilepsy 1 | 12

Tissue

Blood and immune system 34 | 16,909
Cardiovascular System 34 | 15,192
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Skin and soft tissues 34 | 17,230
Liver and Pancreas 33 | 16,750
Respiratory system 33 | 16,393
Urinary Tract 33 | 16,678

Target Family

Enzyme 33 | 4,145
Non-IDG 1 | 12,091
Transporter 1 | 473

GO Function

phosphatase activity 35 | 35
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostatic acid phosphatase ACPP Tchem Enzyme -2.37625 249.3 525
Dual specificity protein phosphatase 13 isoform B DUSP13 Tbio Enzyme -1.26330 34.4 180
Dual specificity protein phosphatase 18 DUSP18 Tbio Enzyme -0.69461 5.47 26
Protein phosphatase 1F PPM1F Tbio Enzyme -1.53852 37.0 236
Dual specificity protein phosphatase 12 DUSP12 Tbio Enzyme -1.78052 60.2 167
Pseudouridine-5'-phosphatase PUDP Tdark Enzyme -0.41683 1.93 79
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.98955 114.2 298
Dual specificity protein phosphatase 16 DUSP16 Tbio Enzyme -1.32944 22.4 159
Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 Tclin Transporter -1.68777 43.2 399
Receptor-type tyrosine-protein phosphatase O PTPRO Tbio Enzyme -1.70513 58.0 56