Development Level

Tchem 24 | 1,890
Tbio 18 | 10,625
Tclin 10 | 602
Tdark 5 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 4 | 145
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
hyperactivity 2 | 108
abnormal body wall morphology 1 | 7
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal gait 1 | 51
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 3
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal maxilla morphology 1 | 16
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal tail morphology 1 | 17
abnormal vibrissa morphology 1 | 17
brachydactyly 1 | 2
cleft palate 1 | 6
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
hemorrhage 1 | 12
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased heart weight 1 | 37
increased lean body mass 1 | 107

Disease

osteosarcoma 29 | 7,933
ovarian cancer 27 | 8,492
psoriasis 24 | 6,685
glioblastoma 17 | 5,572
lung cancer 17 | 4,473
atypical teratoid / rhabdoid tumor 15 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
medulloblastoma, large-cell 14 | 6,234
ductal carcinoma in situ 13 | 1,745
invasive ductal carcinoma 13 | 2,950
malignant mesothelioma 13 | 3,163
Cancer 12 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
pilocytic astrocytoma 12 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
pediatric high grade glioma 11 | 2,712
Breast cancer 10 | 3,099
Carcinoma 9 | 2,147
acute quadriplegic myopathy 9 | 1,157
astrocytoma 9 | 1,493
breast carcinoma 9 | 1,614
lung adenocarcinoma 9 | 2,714
non-small cell lung cancer 9 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
ependymoma 8 | 2,514
oligodendroglioma 8 | 2,849
primitive neuroectodermal tumor 8 | 3,031
ulcerative colitis 8 | 2,087
active Crohn's disease 7 | 918
lung carcinoma 7 | 2,844
astrocytic glioma 6 | 2,241
group 3 medulloblastoma 6 | 2,254
juvenile dermatomyositis 6 | 1,189
pancreatic cancer 6 | 2,300
pituitary cancer 6 | 1,972
spina bifida 6 | 1,064
tuberculosis 6 | 1,563
Alzheimer's disease 5 | 644
Atopic dermatitis 5 | 944
Hypertension 5 | 293
Multiple myeloma 5 | 1,328
Pain agnosia 5 | 99
Pick disease 5 | 1,893
acute myeloid leukemia 5 | 785
adrenocortical carcinoma 5 | 1,427
adult high grade glioma 5 | 2,148
colon cancer 5 | 1,475
cutaneous lupus erythematosus 5 | 1,056
cystic fibrosis 5 | 1,670
group 4 medulloblastoma 5 | 1,875
posterior fossa group A ependymoma 5 | 1,511
posterior fossa group B ependymoma 5 | 1,530
Peripheral Neuropathy 4 | 303
Rheumatoid Arthritis 4 | 1,171
Schizophrenia 4 | 503
Waldenstrons macroglobulinemia 4 | 765
atypical teratoid/rhabdoid tumor 4 | 1,095
diabetes mellitus 4 | 1,663
esophageal adenocarcinoma 4 | 737
glioblastoma multiforme 4 | 347
interstitial cystitis 4 | 2,299
medulloblastoma 4 | 1,524
non-small cell lung carcinoma 4 | 413
primary pancreatic ductal adenocarcinoma 4 | 1,271
sonic hedgehog group medulloblastoma 4 | 1,482
Acquired immunodeficiency syndrome 3 | 164
Autistic Disorder 3 | 320
Endometriosis 3 | 535
Hereditary factor VIII deficiency disease 3 | 3
Hypertensive disease 3 | 193
Kidney disease 3 | 397
Mammary Neoplasms 3 | 410
Mammary Neoplasms, Experimental 3 | 150
Neurodegenerative disease 3 | 383
Nocturnal enuresis 3 | 6
Partial Central Diabetes Insipidus 3 | 3
Prostatic Neoplasms 3 | 471
chronic kidney disease 3 | 90
dermatomyositis 3 | 967
fibroadenoma 3 | 557
gastric carcinoma 3 | 832
head and neck cancer 3 | 270
nephrosclerosis 3 | 329
non primary Sjogren syndrome sicca 3 | 840
von Willebrand disorder 3 | 3
Amyotrophic Lateral Sclerosis 2 | 432
Atherosclerosis 2 | 275
Becker muscular dystrophy 2 | 187
Cocaine-Related Disorders 2 | 88
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Neuropathy 2 | 210
Polycystic Ovary Syndrome 2 | 335
Vascular disease 2 | 281
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic rhinosinusitis 2 | 512
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Cardiovascular System 55 | 17,958
Digestive Tract 55 | 18,473
Endocrine System 55 | 18,512
Female tissues 55 | 18,647
Nervous System 55 | 18,561
Skin and soft tissues 55 | 18,115
Male tissues 54 | 17,969
Urinary Tract 54 | 18,444
Liver and Pancreas 53 | 18,136
Respiratory system 53 | 17,484
Blood and immune system 51 | 17,995

Target Family

Enzyme 28 | 4,146
GPCR 16 | 408
Non-IDG 8 | 11,969
Kinase 4 | 634
Transcription Factor 1 | 1,400

GO Function

peptide binding 57 | 57
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.04546 78.8 485
Aminopeptidase N ANPEP Tchem Enzyme -3.26833 1759.9 972
Calreticulin CALR Tbio Non-IDG -3.16449 1423.9 650
Orexin receptor type 2 HCRTR2 Tclin GPCR -1.44237 24.9 223
Orexin receptor type 1 HCRTR1 Tclin GPCR -2.15846 138.3 270
Gonadotropin-releasing hormone receptor GNRHR Tclin GPCR -2.61137 425.1 280
Neuropeptide FF receptor 2 NPFFR2 Tchem GPCR -1.61085 35.0 148
Geranylgeranyl transferase type-1 subunit beta PGGT1B Tchem Enzyme -1.51052 29.4 60
Thyrotropin-releasing hormone-degrading ectoenzyme TRHDE Tdark Enzyme -1.61185 36.9 43
Puromycin-sensitive aminopeptidase-like protein NPEPPSL1 Tdark Enzyme 0.00000 0