Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating bilirubi... 1 | 19
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
increased blood urea nitrogen ... 1 | 48
increased heart weight 1 | 62
premature death 1 | 5
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 8 | 8,520
Breast cancer 7 | 3,578
Carcinoma 7 | 11,493
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
group 3 medulloblastoma 6 | 4,104
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
pancreatic cancer 6 | 2,398
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
primary pancreatic ductal adenocarcinoma 5 | 1,109
Cancer 4 | 2,499
Duchenne muscular dystrophy 4 | 601
Schizophrenia 4 | 1,160
adult high grade glioma 4 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Breast Neoplasms 3 | 445
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
limb girdle muscular dystrophy 2A 3 | 213
nasopharyngeal carcinoma 3 | 1,058
primitive neuroectodermal tumor 3 | 3,035
tuberculosis and treatment for 3 months 3 | 179
Amyotrophic lateral sclerosis 2 | 451
Arthritis 2 | 290
Bipolar Disorder 2 | 666
Brain disease 2 | 96
Cell Transformation, Neoplastic 2 | 97
Deglutition Disorders 2 | 132
Down syndrome 2 | 499
Dull intelligence 2 | 645
Hypertension 2 | 396
Hypertensive disease 2 | 292
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Neoplasm Invasiveness 2 | 161
Neoplastic Cell Transformation 2 | 89
Nerve Degeneration 2 | 121
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Parkinsonian Disorders 2 | 56
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Pulmonary Fibrosis 2 | 106
Weight Gain 2 | 100
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
fascioscapulohumeral muscular dystrophy 2 | 100
fibroadenoma 2 | 559
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
urothelial carcinoma 2 | 318
Amnesia 1 | 17
Amyloidosis 1 | 67
Arthropathy 1 | 43
Chronic Obstructive Airway Disease 1 | 37
Chronic kidney disease stage 5 1 | 31
Clonus 1 | 18
Febrile Convulsions 1 | 14
Hepatosplenomegaly 1 | 22
Hypotension, Orthostatic 1 | 18
Idiopathic pulmonary arterial hypertension 1 | 40
Lipodystrophy 1 | 40
Lyme disease 1 | 26
Memory Disorders 1 | 40
Microscopic hematuria 1 | 9
Neurodegenerative Diseases 1 | 38
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Plaque, Amyloid 1 | 2
Pulmonary Disease, Chronic Obstructive 1 | 31
Renal glomerular disease 1 | 12
Tarsal Coalition 1 | 12

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634

GO Function

peptidase activator activity 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial CLPX Tbio Enzyme -2.32024 211.2 76
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Fibulin-1 FBLN1 Tbio Non-IDG -1.97380 101.1 218
Procollagen C-endopeptidase enhancer 1 PCOLCE Tbio Enzyme -1.73849 56.6 153
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Procollagen C-endopeptidase enhancer 2 PCOLCE2 Tbio Enzyme -0.74149 6.98 109
Matrix metalloproteinase-14 MMP14 Tchem Enzyme -3.01152 1087.9 840
Amyloid-beta A4 protein APP Tchem Non-IDG -3.99225 9853.3 2781
Caveolin-1 CAV1 Tbio Non-IDG -3.35685 2432.3 855