Development Level

Tbio 8 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

decreased grip strength 1 | 116
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208

Disease

Carcinoma 4 | 11,493
atypical teratoid / rhabdoid tumor 4 | 5,112
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
ulcerative colitis 3 | 1,819
Breast cancer 2 | 3,578
Contracture 2 | 96
Contracture of joint 2 | 93
Dull intelligence 2 | 645
Failure to gain weight 2 | 365
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of pelvic girdle bone morphology 1 | 37
Acquired scoliosis 1 | 281
Adrenoleukodystrophy 1 | 29
Anteverted nostril 1 | 191
Atopic dermatitis 1 | 952
Blind Vision 1 | 111
Blindness 1 | 88
Blindness, Legal 1 | 110
Broad flat nasal bridge 1 | 236
Byzanthine arch palate 1 | 194
Carcinoma, Hepatocellular 1 | 228
Cerebral atrophy 1 | 178
Cholestasis 1 | 155
Chondrodysplasia punctata 1 | 41
Concave bridge of nose 1 | 195
Curvature of spine 1 | 282
Decreased visual acuity, progressive 1 | 36
Degenerative brain disorder 1 | 100
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Diabetes Mellitus, Experimental 1 | 108
Electroencephalogram abnormal 1 | 101
Epilepsy 1 | 792
Extinguished electroretinogram 1 | 15
Fatty liver disease 1 | 103
Generalized osteopenia 1 | 99
Hallucinations 1 | 34
Hallucinations, Sensory 1 | 33
Hepatomegaly 1 | 285
High forehead 1 | 102
Human immunodeficiency virus infectious disease 1 | 138
Increased neuronal autofluorescent lipopigment 1 | 7
Infantile Refsum disease 1 | 23
Irritation - emotion 1 | 68
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Liver carcinoma 1 | 240
Liver neoplasms 1 | 130
Loss of speech 1 | 16
Macular degeneration 1 | 65
Meckel's diverticulum 1 | 5
Muscle Spasticity 1 | 195
Myoclonus 1 | 74
Nasal bridge wide 1 | 236
Neurodegenerative disease 1 | 414
Neuronal ceroid lipofuscinosis 1 | 28
Neuronal ceroid lipofuscinosis 1 1 | 15
Neuronal lipopigments 1 | 7
Osteopenia 1 | 99
Progressive microcephaly 1 | 32
Progressive visual loss 1 | 36
Pruritus 1 | 58
Refsum disease 1 | 20
Retinal Degeneration 1 | 106
Rhizomelia 1 | 25
Rickets 1 | 49
Seizures 1 | 596
Short upper arms 1 | 16
Sleep disturbances 1 | 37
Steatorrhea 1 | 34
Supratentorial atrophy 1 | 94
Tall forehead 1 | 102
Wide bregma sutures 1 | 46
Zellweger syndrome 1 | 37
non-small cell lung carcinoma 1 | 317
sarcoidosis 1 | 370
tuberculosis 1 | 2,010

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Liver and Pancreas 10 | 16,750
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192
Female tissues 9 | 17,400
Male tissues 9 | 17,142

Target Family

Enzyme 11 | 4,145

GO Function

palmitoyl-CoA hydrolase activi... 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acyl-coenzyme A thioesterase 4 ACOT4 Tbio Enzyme -0.53787 2.87 58
Acyl-coenzyme A thioesterase 1 ACOT1 Tdark Enzyme -2.14311 129.6 43
Palmitoyl-protein thioesterase 1 PPT1 Tbio Enzyme -2.63966 433.8 305
Putative cytosolic acyl coenzyme A thioester hydrolase-like ACOT7L Tdark Enzyme 0.00000 0
Dihydroxyacetone phosphate acyltransferase GNPAT Tchem Enzyme -1.82166 68.1 178
Cytosolic acyl coenzyme A thioester hydrolase ACOT7 Tbio Enzyme -2.06780 111.8 102
Acyl-coenzyme A thioesterase 2, mitochondrial ACOT2 Tbio Enzyme -1.19955 15.4 93
Acyl-coenzyme A thioesterase THEM4 THEM4 Tbio Enzyme -2.24800 171.4 69
Acyl-coenzyme A thioesterase 8 ACOT8 Tbio Enzyme -2.41856 254.6 180
Bile acid-CoA:amino acid N-acyltransferase BAAT Tbio Enzyme -1.71631 50.3 126