Development Level

Tbio 31 | 10,625
Tchem 23 | 1,890
Tdark 4 | 7,003
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal behavior 2 | 226
abnormal iris morphology 2 | 12
decreased circulating LDL chol... 2 | 37
increased lean body mass 2 | 107
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
cataract 1 | 26
cleft palate 1 | 6
corneal opacity 1 | 25
cyanosis 1 | 6
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating magnesiu... 1 | 11
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
hypoactivity 1 | 89
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating potassiu... 1 | 31
increased grip strength 1 | 83
increased mean platelet volume 1 | 19
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
tremors 1 | 34

Disease

ovarian cancer 35 | 8,484
osteosarcoma 33 | 7,933
lung cancer 27 | 4,466
Cancer 26 | 2,346
medulloblastoma, large-cell 23 | 6,234
psoriasis 22 | 6,685
glioblastoma 20 | 5,572
Carcinoma 16 | 2,147
atypical teratoid / rhabdoid tumor 15 | 4,369
oligodendroglioma 15 | 2,849
astrocytic glioma 13 | 2,241
malignant mesothelioma 13 | 3,162
primitive neuroectodermal tumor 13 | 3,031
Breast cancer 12 | 3,094
pilocytic astrocytoma 12 | 3,086
diabetes mellitus 11 | 1,663
ependymoma 10 | 2,514
invasive ductal carcinoma 10 | 2,950
juvenile dermatomyositis 10 | 1,189
non-small cell lung cancer 9 | 2,798
Multiple myeloma 8 | 1,327
Pick disease 8 | 1,893
Rheumatoid Arthritis 8 | 1,160
acute quadriplegic myopathy 8 | 1,157
adrenocortical carcinoma 8 | 1,427
adult high grade glioma 8 | 2,148
group 4 medulloblastoma 8 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung adenocarcinoma 8 | 2,713
lung carcinoma 8 | 2,844
pediatric high grade glioma 8 | 2,712
subependymal giant cell astrocytoma 8 | 2,287
Intellectual disability 7 | 573
atypical teratoid/rhabdoid tumor 7 | 1,095
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 2,254
pancreatic cancer 7 | 2,300
Alzheimer's disease 6 | 644
Amyotrophic Lateral Sclerosis 6 | 431
Lung Neoplasms 6 | 171
Prostatic Neoplasms 6 | 471
astrocytoma 6 | 1,493
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
medulloblastoma 6 | 1,524
pituitary cancer 6 | 1,972
posterior fossa group A ependymoma 6 | 1,511
spina bifida 6 | 1,064
Adenocarcinoma 5 | 115
HIV Infections 5 | 100
Pancreatic Neoplasm 5 | 79
Parkinson's disease 5 | 364
Stomach Neoplasms 5 | 282
dermatomyositis 5 | 933
nasopharyngeal carcinoma 5 | 1,056
non-small cell lung carcinoma 5 | 413
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
sonic hedgehog group medulloblastoma 5 | 1,482
Bladder Neoplasm 4 | 109
Endometriosis 4 | 535
Heart disease 4 | 279
Kidney disease 4 | 396
Lymphoid leukemia 4 | 69
Mammary Neoplasms 4 | 410
Neoplastic Cell Transformation 4 | 81
Neoplastic Syndromes, Hereditary 4 | 48
Sezary Syndrome 4 | 26
Small cell carcinoma of lung 4 | 45
Toxic encephalopathy 4 | 131
Vascular disease 4 | 281
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
cystic fibrosis 4 | 1,665
glioblastoma multiforme 4 | 347
pancreatic carcinoma 4 | 567
progressive supranuclear palsy 4 | 674
Acute kidney injury 3 | 65
Adenoma 3 | 165
Arthritis 3 | 248
Cleft Lip 3 | 91
Cockayne syndrome 3 | 54
Glioma 3 | 65
Huntington's disease 3 | 72
IGA Glomerulonephritis 3 | 454
Liver carcinoma 3 | 217
Melanoma 3 | 261
Neoplasm Invasiveness 3 | 127
Neoplasm Metastasis 3 | 138
Neurodegenerative disease 3 | 383
Nijmegen breakage syndrome 3 | 23
Peripheral Neuropathy 3 | 303
Squamous cell carcinoma 3 | 94
Squamous cell carcinoma of esophagus 3 | 82
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 780
cutaneous lupus erythematosus 3 | 1,056
tuberculosis 3 | 1,557
ulcerative colitis 3 | 2,087

Tissue

Blood and immune system 59 | 17,995
Digestive Tract 59 | 18,473
Female tissues 59 | 18,647
Liver and Pancreas 59 | 18,136
Male tissues 59 | 17,969
Nervous System 59 | 18,561
Cardiovascular System 58 | 17,958
Endocrine System 58 | 18,512
Respiratory system 57 | 17,484
Skin and soft tissues 57 | 18,115
Urinary Tract 57 | 18,444

Target Family

Non-IDG 24 | 11,971
Epigenetic 14 | 242
Enzyme 9 | 4,146
Kinase 8 | 634
Transcription Factor 4 | 1,400

GO Function

p53 binding 59 | 59
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Ubiquitin carboxyl-terminal hydrolase 7 USP7 Tchem Enzyme -2.17350 165.7 375
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.80641 78.9 225
E3 ubiquitin-protein ligase rififylin RFFL Tbio Enzyme -2.01828 103.8 168
Pituitary tumor-transforming gene 1 protein-interacting protein PTTG1IP Tbio Non-IDG -0.83380 7.59 87
TP53-regulating kinase TP53RK Tbio Kinase -1.14926 16.8 178
CDKN2A-interacting protein CDKN2AIP Tbio Non-IDG -0.72216 6.39 131
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.79080 637.1 113