Development Level

Tbio 21 | 10,625
Tchem 10 | 1,890
Tclin 8 | 602
Tdark 3 | 7,003

IMPC Phenotype

abnormal bone structure 1 | 131
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased circulating choleste... 1 | 85
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
decreased mean platelet volume 1 | 12
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased fasted circulating g... 1 | 68
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260
small kidney 1 | 10

Disease

psoriasis 19 | 6,685
Cancer 17 | 2,346
osteosarcoma 14 | 7,933
ovarian cancer 13 | 8,491
Prostatic Neoplasms 11 | 471
medulloblastoma, large-cell 11 | 6,234
interstitial cystitis 10 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
lung adenocarcinoma 10 | 2,714
Anemia 9 | 252
Thalassemia 9 | 46
lung cancer 9 | 4,473
lung carcinoma 9 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
tuberculosis 9 | 1,563
Liver disease 8 | 219
diabetes mellitus 8 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
non-small cell lung cancer 8 | 2,798
pancreatic cancer 8 | 2,300
Hemolytic anemia 7 | 70
Malaria 7 | 140
ductal carcinoma in situ 7 | 1,745
glioblastoma 7 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
oligodendroglioma 7 | 2,849
pituitary cancer 7 | 1,972
Breast cancer 6 | 3,098
Hypertension 6 | 293
Mammary Neoplasms 6 | 410
Sickle Cell Anemia 6 | 54
breast carcinoma 6 | 1,614
invasive ductal carcinoma 6 | 2,950
ulcerative colitis 6 | 2,087
adrenocortical carcinoma 5 | 1,427
atypical teratoid / rhabdoid tumor 5 | 4,369
cutaneous lupus erythematosus 5 | 1,056
mucosa-associated lymphoid tissue lymphoma 5 | 480
posterior fossa group A ependymoma 5 | 1,511
Acute kidney injury 4 | 65
Adverse reaction to drug 4 | 54
Chloracne 4 | 32
Drug-Induced Liver Injury 4 | 118
Endometriosis 4 | 535
Liver carcinoma 4 | 217
Peripheral Neuropathy 4 | 303
Schizophrenia 4 | 503
Vascular disease 4 | 281
adrenocortical adenoma 4 | 134
adult high grade glioma 4 | 2,148
astrocytic glioma 4 | 2,241
chronic rhinosinusitis 4 | 512
ependymoma 4 | 2,514
group 3 medulloblastoma 4 | 2,254
head and neck cancer and chronic obstructive pulmonary disease 4 | 237
medulloblastoma 4 | 1,524
pediatric high grade glioma 4 | 2,712
periodontitis 4 | 269
pilocytic astrocytoma 4 | 3,086
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
substance-related disorder 4 | 104
Acute chest syndrome 3 | 9
Adenocarcinoma 3 | 115
Cardiomegaly 3 | 66
Congenital adrenal hyperplasia 3 | 74
Delta-beta-thalassemia 3 | 3
Dystonia 3 | 77
Epilepsy 3 | 346
FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1 3 | 3
Heart disease 3 | 279
Hepatitis C 3 | 90
Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome 3 | 4
Human immunodeficiency virus infection 3 | 6
Hypogonadism 3 | 70
Kidney disease 3 | 397
Liver Cirrhosis, Experimental 3 | 108
Lung Neoplasms 3 | 171
Male infertility 3 | 170
Parkinson Disease 3 | 105
Parkinson's disease 3 | 364
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 42
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
head and neck cancer 3 | 270
hepatocellular carcinoma 3 | 550
malignant mesothelioma 3 | 3,163
nasopharyngeal carcinoma 3 | 1,056
non primary Sjogren syndrome sicca 3 | 840
pancreatic carcinoma 3 | 567
sonic hedgehog group medulloblastoma 3 | 1,482
Atrial Fibrillation 2 | 110
Coronary artery disease 2 | 240
Essential Hypertension 2 | 82
Hyperandrogenism 2 | 32
Polycystic Ovary Syndrome 2 | 334
Prostate cancer 2 | 172
active Crohn's disease 2 | 918

Tissue

Digestive Tract 42 | 18,472
Endocrine System 42 | 18,511
Female tissues 42 | 18,646
Nervous System 42 | 18,560
Skin and soft tissues 42 | 18,114
Urinary Tract 42 | 18,443
Blood and immune system 41 | 17,994
Cardiovascular System 41 | 17,957
Liver and Pancreas 41 | 18,135
Male tissues 41 | 17,968
Respiratory system 41 | 17,483

Target Family

Non-IDG 30 | 11,969
Enzyme 12 | 4,146

GO Function

oxygen binding 42 | 42
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hemoglobin subunit zeta HBZ Tbio Non-IDG -2.36868 235.4 158
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase CYP8B1 Tbio Enzyme -1.62014 38.3 100
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.53853 3553.5 340
Myoglobin MB Tbio Non-IDG -3.93607 8413.2 705
Hemoglobin subunit epsilon HBE1 Tbio Non-IDG -3.50861 3125.3 91
Cytochrome P450 2E1 CYP2E1 Tbio Non-IDG -3.39793 2573.0 350
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.31421 2022.5 420
Hemoglobin subunit beta HBB Tchem Non-IDG -3.55342 3463.0 211
Cytochrome P450 3A5 CYP3A5 Tclin Enzyme -2.80197 609.8 100
Cytochrome P450 2B6 CYP2B6 Tchem Non-IDG -3.69934 5025.3 171