Development Level

Tbio 2 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73

Disease

Astrocytoma, Pilocytic 2 | 3,081
Carcinoma 2 | 11,493
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
Actinomycosis 1 | 9
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Autosomal recessive predisposition 1 | 1,442
Cataract 1 | 297
Cognitive delay 1 | 608
Epiglottitis 1 | 3
Global developmental delay 1 | 608
Hypotrophic malar bone 1 | 129
Malar flattening 1 | 129
Malocclusion 1 | 57
Mental and motor retardation 1 | 608
Multiple myeloma 1 | 1,332
Papillary thyroid carcinoma 1 | 43
RETINAL DYSTROPHY, JUVENILE CATARACTS, AND SHORT STATURE SYNDROME 1 | 2
Respiratory Failure 1 | 104
Retinal Dystrophies 1 | 33
Ritter's disease 1 | 10
Short stature 1 | 531
Tinea favosa 1 | 3
Toxic shock syndrome 1 | 28
Upward slant of palpebral fissure 1 | 75
Urethral obstruction 1 | 5
Widely spaced teeth 1 | 31
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
ductal carcinoma in situ 1 | 1,745
glioblastoma 1 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
non primary Sjogren syndrome sicca 1 | 891
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
progressive supranuclear palsy 1 | 676
tuberculosis and treatment for 6 months 1 | 409
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 4 | 16,909
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Cardiovascular System 3 | 15,192
Respiratory system 3 | 16,393

Target Family

Enzyme 3 | 4,145
Non-IDG 1 | 12,091

GO Function

oxidoreductase activity, actin... 4 | 4
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-conjugating enzyme E2 variant 3 UEVLD Tdark Non-IDG 0.07 1.05 94
Aldo-keto reductase family 1 member B15 AKR1B15 Tbio Enzyme -0.24304 2.90 6
Prostamide/prostaglandin F synthase FAM213B Tdark Enzyme -0.13033 0.76 60
Retinol dehydrogenase 11 RDH11 Tbio Enzyme -3.15682 1370.1 150