Development Level

Tbio 6 | 11,445
Tchem 6 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

decreased basophil cell number 1 | 16
decreased circulating iron lev... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
vertebral transformation 1 | 12

Disease

medulloblastoma, large-cell 8 | 6,241
Carcinoma 7 | 11,493
osteosarcoma 7 | 7,950
ovarian cancer 6 | 8,520
psoriasis 5 | 6,694
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung cancer 4 | 4,740
invasive ductal carcinoma 3 | 2,951
primitive neuroectodermal tumor 3 | 3,035
Polycythemia 2 | 25
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
Amyotrophic lateral sclerosis 1 | 451
Anemia 1 | 365
Anemia of prematurity 1 | 1
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Autoimmune polyendocrine syndrome 1 | 6
Breast Neoplasms 1 | 445
Breast cancer 1 | 3,578
Broad nasal tip 1 | 28
Cleft Lip 1 | 141
Cleft Palate 1 | 271
Cryptorchidism 1 | 296
Dental pulp necrosis 1 | 10
Dull intelligence 1 | 645
Erythrocytosis, Familial, 3 1 | 1
Hematocrit increased 1 | 5
Hemoglobin increased 1 | 6
Increased red blood cell mass 1 | 4
Intellectual disability 1 | 1,016
Large hand 1 | 18
Laryngotracheitis 1 | 10
Liver neoplasms 1 | 130
Long face 1 | 71
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Mild Mental Retardation 1 | 70
Neoplasm Invasiveness 1 | 161
Ossifying fibroma 1 | 15
Persistent generalized lymphadenopathy 1 | 15
Pick disease 1 | 1,894
Pilocytic astrocytoma 1 | 56
Poor school performance 1 | 645
Primary polycythemia 1 | 8
RETINITIS PIGMENTOSA 43 1 | 4
Retinitis pigmentosa 71 1 | 2
Siderius X-linked mental retardation syndrome 1 | 1
Small testicle 1 | 75
Syndromic X-linked intellectual disability Siderius type 1 | 1
TOBACCO ADDICTION, SUSCEPTIBILITY TO 1 | 12
TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) 1 | 12
Vascular disease 1 | 319
cutaneous lupus erythematosus 1 | 1,057
ductal carcinoma in situ 1 | 1,745
fascioscapulohumeral muscular dystrophy 1 | 100
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
interstitial cystitis 1 | 2,312
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
mucosa-associated lymphoid tissue lymphoma 1 | 484
pancreatic cancer 1 | 2,398
pituitary cancer 1 | 1,972

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145
Epigenetic 3 | 242

GO Function

oxidoreductase activity, actin... 14 | 14
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane prolyl 4-hydroxylase P4HTM Tchem Enzyme -2.70235 473.8 159
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 ALKBH4 Tdark Enzyme -0.51663 4.07 103
Nucleic acid dioxygenase ALKBH1 ALKBH1 Tbio Enzyme -2.09946 119.6 149
Lysine-specific demethylase 7A KDM7A Tchem Epigenetic -1.02284 9.06 88
Ribosomal oxygenase 1 RIOX1 Tbio Epigenetic 0.00000 67
Alkylated DNA repair protein alkB homolog 8 ALKBH8 Tbio Non-IDG -1.26833 18.0 107
RNA demethylase ALKBH5 ALKBH5 Tbio Enzyme -1.60956 36.8 72
Egl nine homolog 2 EGLN2 Tchem Non-IDG -2.03430 0.00000 318
Histone lysine demethylase PHF8 PHF8 Tchem Epigenetic -1.50422 40.0 77
Hypoxia-inducible factor 1-alpha inhibitor HIF1AN Tbio Non-IDG -1.91636 75.1 429