Development Level

Tdark 4 | 6,588
Tbio 3 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

decreased total body fat amoun... 2 | 207
abnormal heart morphology 1 | 162
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
enlarged heart 1 | 210
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased lean body mass 1 | 172
trunk curl 1 | 16

Disease

Carcinoma 9 | 11,493
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
malignant mesothelioma 3 | 3,232
tuberculosis 3 | 2,010
Autosomal recessive predisposition 2 | 1,442
Bone Diseases, Metabolic 2 | 14
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Liver Cirrhosis 2 | 181
Metabolic Bone Disorder 2 | 11
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
subependymal giant cell astrocytoma 2 | 2,287
Abnormal cortical bone morphology 1 | 22
Abnormality of cholesterol metabolism 1 | 3
Abnormality of the femur 1 | 6
Abnormality of the metaphyses 1 | 48
Abnormality of the tibia 1 | 9
Abnormality of vision 1 | 40
Abnormally-shaped vertebrae 1 | 31
Angina Pectoris 1 | 32
Autosomal recessive congenital ichthyosis 1 | 11
Bleeding time prolonged 1 | 31
Bone marrow hypocellularity 1 | 20
Camurati-Engelmann Syndrome 1 | 5
Cerebrotendinous xanthomatosis 1 | 13
Cholelithiasis 1 | 33
Cholera 1 | 34
Congenital Nonbullous Ichthyosiform Erythroderma 1 | 16
Congenital ichthyosiform erythroderma 1 | 28
Craniofacial hyperostosis 1 | 11
Decreased platelet count 1 | 111
Delusions 1 | 11
Diaphyseal thickening 1 | 11
Drug Hypersensitivity 1 | 34
Drug allergy 1 | 36
Ductus Arteriosus, Patent 1 | 6
Ecchymosis 1 | 66
Ectropion 1 | 38
Enlargement of craniofacial bones 1 | 11
Epistaxis 1 | 43
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Eyelid Xanthoma 1 | 5
Female stress incontinence 1 | 7
Femoral neuropathy 1 | 3
Gaucher disease type 3 1 | 67
Hallucinations 1 | 34
Hallucinations, Sensory 1 | 33
Hypertrophy of craniofacial bones 1 | 11
Increased tendency to bruise 1 | 66
Legg-Calve-Perthes disease 1 | 14
Lymphoid leukemia 1 | 160
Metal allergy 1 | 5
Muscle Weakness 1 | 170
Myelofibrosis 1 | 14
Myocardial Infarction 1 | 151
Myoclonus 1 | 74
Neurogenic bowel 1 | 6
Osteonecrosis 1 | 27
Osteosclerosis 1 | 31
Pallor of optic disc 1 | 39
Peripheral Neuropathy 1 | 134
Peroneal nerve paralysis 1 | 11
Pseudobulbar palsy 1 | 11
Pulmonary embolism 1 | 55
Pyramidal sign 1 | 29
Refractory anemias 1 | 6
Rickets 1 | 49
Scrub typhus 1 | 7
Serum cholesterol raised 1 | 22
Spasm of cerebral arteries 1 | 3
Spondylosis 1 | 16
Stevens-Johnson syndrome 1 | 92
Thick craniofacial bones 1 | 11
Thrombocytopenia 1 | 197
Tremor 1 | 113
Ulcerative stomatitis 1 | 4
Xanthelasma of periocular region 1 | 5
Xanthoma 1 | 5
Xanthoma of periocular region 1 | 5
inflammatory breast cancer 1 | 286
nutritional deficiency disease 1 | 9

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192
Nervous System 8 | 16,725

Target Family

Enzyme 6 | 4,145
Non-IDG 4 | 12,091

GO Function

oxidoreductase activity, actin... 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 OGFOD2 Tdark Enzyme 0.00000 86
Vitamin D 25-hydroxylase CYP2R1 Tbio Enzyme -1.96830 95.4 152
Putative inactive cytochrome P450 family member 4Z2 CYP4Z2P Tdark Non-IDG -0.68998 9.87 0
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -2.03967 107.1 42
Prostacyclin synthase PTGIS Tchem Enzyme -2.55019 341.8 152
Thromboxane-A synthase TBXAS1 Tchem Enzyme -3.16512 1395.9 264
Cytochrome P450 4V2 CYP4V2 Tbio Non-IDG -2.73252 534.7 128
Sterol 26-hydroxylase, mitochondrial CYP27A1 Tchem Enzyme -2.99010 980.2 164
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 OGFOD3 Tdark Enzyme 0.60 0.25 12
Cytochrome P450 20A1 CYP20A1 Tdark Non-IDG -0.62570 3.37 166