Development Level

Tclin 6 | 613
Tbio 1 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal epididymis morphology 1 | 42
aorta stenosis 1 | 2
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
preweaning lethality, complete... 1 | 979
thin ventricular wall 1 | 24

Disease

Carcinoma 8 | 11,493
Kidney cancer 5 | 2,613
Eaton-Lambert syndrome 4 | 40
Multiple Sclerosis 4 | 540
Astrocytoma, Pilocytic 3 | 3,081
Atrial Fibrillation 3 | 124
Epilepsy 3 | 792
ependymoma 3 | 4,679
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 2 | 21
Breast cancer 2 | 3,578
Familial atrial fibrillation 2 | 23
General anesthesia 2 | 53
Long QT syndrome 2 | 39
Nephroblastoma 2 | 51
Seizures 2 | 596
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Abdominal Pain 1 | 98
Adenocarcinoma 1 | 122
Advanced bone age 1 | 35
Atrial Fibrillation, Familial, 3 1 | 2
Atrioventricular block 1 | 35
Autosomal recessive polycystic kidney disease 1 | 41
Birk-Barel syndrome 1 | 8
Brugada syndrome 1 | 29
Cardiac Arrhythmia 1 | 103
Cardiac arrest 1 | 36
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Catecholaminergic polymorphic ventricular tachycardia 1 | 12
Coarse facial features 1 | 108
Congenital sensorineural hearing loss 1 | 12
Dentin sensitivity 1 | 14
Diaphragmatic Hernia 1 | 40
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 32 1 | 1
Elevated heart rate 1 | 25
Epileptic encephalopathy 1 | 26
Episodic ataxia 1 | 22
Fetal overgrowth 1 | 16
Generalized overgrowth 1 | 16
Gestational diabetes 1 | 26
Gonadoblastoma 1 | 34
Hearing Loss, Noise-Induced 1 | 5
Heart conduction disease 1 | 83
Hepatoblastoma 1 | 19
Hypertension, Pulmonary 1 | 37
Intestinal Neoplasms 1 | 12
Jervell-Lange Nielsen syndrome 1 | 4
Language Development Disorders 1 | 11
Large, late-closing fontanelle 1 | 46
Long QT syndrome 1 1 | 20
Macular degeneration 1 | 65
Myoclonus 1 | 74
Neonatal hypoglycemia 1 | 17
Neurodegenerative Diseases 1 | 38
Neurodegenerative Disorders 1 | 79
Noise-induced hearing loss 1 | 5
Overgrowth 1 | 16
Palpitations 1 | 18
Panic disorder 1 | 61
Paroxysmal atrial fibrillation 1 | 14
Polycystic kidney disease 2 1 | 11
Polycystic liver disease 1 | 16
Primary pulmonary hypertension 1 | 14
Prolonged QT interval 1 | 15
Prominent back of the head 1 | 21
Prominent eyes 1 | 96
Prominent globes 1 | 96
Prominent occiput 1 | 21
Protruding eyes 1 | 96
Retinal Diseases 1 | 55
Romano-Ward Syndrome 1 | 12
Sensorineural hearing loss 1 | 106
Short QT syndrome 1 | 12
Situs Inversus 1 | 65
Sudden Cardiac Death 1 | 29
Sudden infant death syndrome 1 | 32
Syncope 1 | 22
Thickened facial skin with coarse facial features 1 | 108
Timothy syndrome 1 | 11
Torsades de Pointes 1 | 8
Tremor 1 | 113
Type 1 diabetes mellitus 1 | 109
Vascular Diseases 1 | 16
Ventricular Fibrillation 1 | 17
Wide bregma sutures 1 | 46
Wilms Tumor 1 | 28

Tissue

Endocrine System 8 | 18,159
Nervous System 8 | 16,725
Digestive Tract 7 | 17,369
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192

Target Family

Ion Channel 7 | 344
Transcription Factor 1 | 1,400

GO Function

outward rectifier potassium ch... 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Potassium voltage-gated channel subfamily A member 3 KCNA3 Tclin Ion Channel -2.69107 522.2 286
Potassium channel subfamily K member 18 KCNK18 Tclin Ion Channel -1.78869 66.5 88
Potassium channel subfamily K member 2 KCNK2 Tclin Ion Channel -2.75349 578.2 86
Potassium voltage-gated channel subfamily A member 5 KCNA5 Tclin Ion Channel -2.61528 428.3 209
RE1-silencing transcription factor REST Tbio Transcription Factor -2.44426 245.2 178