Development Level

Tbio 12 | 11,651
Tdark 2 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased mean corpuscular hem... 1 | 50
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278

Disease

osteosarcoma 9 | 7,950
Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
lung cancer 5 | 4,740
Autosomal recessive predisposition 3 | 1,442
Short stature 3 | 531
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
Barrett's esophagus 2 | 182
Cancer 2 | 2,499
Cerebellar Ataxia 2 | 304
Cognitive delay 2 | 608
Dull intelligence 2 | 645
Epilepsy 2 | 792
Generalized hyperpigmentation 2 | 22
Global developmental delay 2 | 608
Intellectual disability 2 | 1,016
Kidney Diseases 2 | 114
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Pick disease 2 | 1,894
Poor school performance 2 | 645
Secondary physiologic amenorrhea 2 | 32
Seizures 2 | 596
Spondyloepimetaphyseal dysplasia 2 | 12
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
cystic fibrosis 2 | 1,696
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Abnormality of female internal genitalia 1 | 13
Abnormality of the fingernails 1 | 51
Abnormality of the pharynx 1 | 19
Acne 1 | 52
Anorectal Malformations 1 | 8
Aplasia/Hypoplasia of the skin 1 | 16
Aplastic Anemia 1 | 21
Asphyxiating thoracic dystrophy 1 | 44
Atrophic condition of skin 1 | 25
Bone marrow hypocellularity 1 | 20
Brain cancer 1 | 30
Bronchioloalveolar Adenocarcinoma 1 | 14
CHARGE syndrome 1 | 26
Choanal Atresia 1 | 42
Cri-Du-Chat syndrome 1 | 16
Dyskeratosis congenita autosomal recessive 1 1 | 3
Dyspnea on exertion 1 | 24
Esophageal Stenosis 1 | 15
Esophagitis 1 | 35
Gait, Unsteady 1 | 29
Gingival Diseases 1 | 19
Hyperpigmented macules 1 | 42
Hypoplastic-absent toenails 1 | 11
Idiopathic pulmonary arterial hypertension 1 | 40
Idiopathic pulmonary fibrosis 1 | 23
Kyphoscoliosis deformity of spine 1 | 60
Large elongated pulp chamber 1 | 14
Leukemia, Lymphoid 1 | 8
Leukokeratosis 1 | 19
Leukoplakia, Oral 1 | 20
Malignant glioma 1 | 26
Neoplasms 1 | 63
Periodontal Diseases 1 | 21
Pitting of nails 1 | 6
Platyspondyly 1 | 56
Premature Menopause 1 | 31
Premature canities 1 | 24
Pulmonary Fibrosis 1 | 106
Retinitis pigmentosa 25 1 | 9
Ridged nails 1 | 14
Rotting teeth 1 | 73
Rough bone trabeculation 1 | 11
Sparse scalp hair 1 | 42
Taurodontism 1 | 14
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Tracheoesophageal Fistula 1 | 36
Urethral Stricture 1 | 18
hypopigmented skin patch 1 | 59

Tissue

Endocrine System 15 | 18,159
Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Male tissues 14 | 17,142
Cardiovascular System 13 | 15,192
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Enzyme 8 | 4,145
Non-IDG 7 | 12,091

GO Function

nucleotidyltransferase activit... 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP-sugar pyrophosphatase NUDT5 Tbio Enzyme -1.49012 32.8 61
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 PAPSS1 Tbio Enzyme -2.41857 281.0 125
Putative nucleotidyltransferase FAM46A FAM46A Tbio Non-IDG -1.01470 12.0 83
Telomerase reverse transcriptase TERT Tchem Enzyme -3.56910 3506.4 643
Putative nucleotidyltransferase FAM46B FAM46B Tdark Non-IDG 0.35 0.42 13
Probable tRNA(His) guanylyltransferase THG1L Tbio Enzyme -0.60206 3.69 71
YrdC domain-containing protein, mitochondrial YRDC Tdark Non-IDG -1.79367 58.5 23
GDP-D-glucose phosphorylase 1 GDPGP1 Tbio Enzyme -0.94612 9.60 37
Putative nucleotidyltransferase FAM46D FAM46D Tbio Non-IDG -1.08932 13.9 65
Mannose-1-phosphate guanyltransferase alpha GMPPA Tbio Enzyme -1.64224 42.1 100