Development Level

Tbio 212 | 10,625
Tdark 69 | 7,003
Tchem 24 | 1,890
Tclin 6 | 602

IMPC Term

preweaning lethality, complete... 12 | 633
abnormal behavior 4 | 226
decreased lean body mass 4 | 195
increased circulating alkaline... 3 | 119
decreased KLRG1-positive NK ce... 2 | 9
decreased body length 2 | 108
decreased caudal vertebrae num... 2 | 49
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased leukocyte cell numbe... 2 | 54
decreased rib number 2 | 59
decreased threshold for audito... 2 | 32
hyperactivity 2 | 108
increased bone mineral density 2 | 52
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased or absent threshold ... 2 | 128
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal lung morphology 1 | 15
abnormal pancreas morphology 1 | 6
abnormal retina morphology 1 | 100
abnormal retinal outer nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal spine curvature 1 | 7
abnormal thoracic vertebrae mo... 1 | 16
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, CD25-p... 1 | 24
decreased IgG2b level 1 | 1
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased NK cell number 1 | 16
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating free fat... 1 | 39
decreased circulating lipase l... 1 | 2
decreased circulating thyroxin... 1 | 5
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased neutrophil cell numb... 1 | 37
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
female infertility 1 | 34
fusion of vertebral arches 1 | 7
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased CD5-positive gamma-d... 1 | 1
increased body weight 1 | 42
increased circulating amylase ... 1 | 13
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
polydactyly 1 | 22
polysyndactyly 1 | 2
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
tremors 1 | 34
vertebral transformation 1 | 12

Disease

ovarian cancer 176 | 8,484
osteosarcoma 151 | 7,933
medulloblastoma, large-cell 114 | 6,234
psoriasis 100 | 6,685
glioblastoma 93 | 5,572
group 3 medulloblastoma 80 | 2,254
atypical teratoid / rhabdoid tumor 79 | 4,369
lung cancer 79 | 4,466
primitive neuroectodermal tumor 69 | 3,031
oligodendroglioma 66 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 62 | 3,289
Pick disease 60 | 1,893
ependymoma 59 | 2,514
Breast cancer 58 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 58 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 52 | 2,956
malignant mesothelioma 50 | 3,162
Multiple myeloma 48 | 1,327
astrocytic glioma 48 | 2,241
lung adenocarcinoma 48 | 2,713
invasive ductal carcinoma 47 | 2,950
acute quadriplegic myopathy 46 | 1,157
pediatric high grade glioma 45 | 2,712
astrocytoma 43 | 1,493
non-small cell lung cancer 43 | 2,798
pilocytic astrocytoma 42 | 3,086
subependymal giant cell astrocytoma 40 | 2,287
Waldenstrons macroglobulinemia 39 | 765
Cancer 38 | 2,346
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,795
progressive supranuclear palsy 37 | 674
dermatomyositis 36 | 933
adult high grade glioma 34 | 2,148
juvenile dermatomyositis 32 | 1,189
lung carcinoma 32 | 2,844
sonic hedgehog group medulloblastoma 32 | 1,482
pancreatic cancer 31 | 2,300
diabetes mellitus 28 | 1,663
pituitary cancer 28 | 1,972
group 4 medulloblastoma 27 | 1,875
Carcinoma 24 | 2,147
colon cancer 24 | 1,475
posterior fossa group B ependymoma 24 | 1,530
tuberculosis and treatment for 6 months 24 | 686
acute myeloid leukemia 23 | 780
ductal carcinoma in situ 23 | 1,745
posterior fossa group A ependymoma 22 | 1,511
Amyotrophic Lateral Sclerosis 21 | 431
breast carcinoma 21 | 1,614
spina bifida 21 | 1,064
tuberculosis 20 | 1,557
adrenocortical carcinoma 17 | 1,427
cystic fibrosis 17 | 1,665
atypical teratoid/rhabdoid tumor 16 | 1,095
hepatocellular carcinoma 16 | 532
interstitial cystitis 16 | 2,299
nasopharyngeal carcinoma 16 | 1,056
primary pancreatic ductal adenocarcinoma 15 | 1,271
ulcerative colitis 15 | 2,087
relapsing-remitting multiple sclerosis 14 | 18
Alzheimer's disease 13 | 644
Rheumatoid Arthritis 13 | 1,160
pancreatic carcinoma 13 | 567
medulloblastoma 12 | 1,524
Azoospermia 11 | 89
Intellectual disability 11 | 573
aldosterone-producing adenoma 11 | 664
Down syndrome 10 | 548
Mammary Neoplasms 10 | 410
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
inflammatory breast cancer 10 | 404
interstitial lung disease 10 | 291
non primary Sjogren syndrome sicca 10 | 840
Atopic dermatitis 9 | 944
Frontotemporal dementia 9 | 41
Infertility 9 | 163
Neurodegenerative disease 9 | 383
Polycystic Ovary Syndrome 9 | 332
gastric carcinoma 9 | 832
HIV Infections 8 | 100
Obesity 8 | 616
Sertoli cell-only syndrome 8 | 36
Stomach Neoplasms 8 | 282
active Crohn's disease 8 | 918
mucosa-associated lymphoid tissue lymphoma 8 | 480
Duchenne muscular dystrophy 7 | 602
Gaucher disease type 1 7 | 171
Male infertility 7 | 170
Oligospermia 7 | 30
Peripheral Neuropathy 7 | 303
Schizophrenia 7 | 501
glioblastoma multiforme 7 | 347
non-small cell lung carcinoma 7 | 413
Acquired metabolic disease 6 | 267
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 557
gastric cancer 6 | 430
cutaneous lupus erythematosus 5 | 1,056
nephrosclerosis 5 | 329
primary Sjogren syndrome 5 | 789

Tissue

Female tissues 306 | 18,647
Male tissues 305 | 17,969
Endocrine System 303 | 18,512
Digestive Tract 300 | 18,473
Blood and immune system 298 | 17,995
Liver and Pancreas 296 | 18,136
Urinary Tract 296 | 18,444
Nervous System 295 | 18,561
Cardiovascular System 292 | 17,958
Respiratory system 290 | 17,484
Skin and soft tissues 290 | 18,115

Target Family

Non-IDG 260 | 11,971
Enzyme 40 | 4,146
Transporter 6 | 473
Epigenetic 4 | 242
GPCR 1 | 406

GO Function

nucleotide binding 311 | 311
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear cap-binding protein subunit 3 NCBP3 Tbio Non-IDG -1.68208 49.3 22
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.20916 14.6 78
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
CUGBP Elav-like family member 4 CELF4 Tbio Non-IDG -1.46075 29.8 40
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
ELAV-like protein 2 ELAVL2 Tbio Non-IDG -2.09180 122.7 196
Putative RNA-binding protein 15B RBM15B Tbio Non-IDG -0.27107 2.59 18
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.28920 20.4 75
Peroxisome proliferator-activated receptor gamma coactivator 1-beta PPARGC1B Tbio Non-IDG -2.61803 420.9 51
Trinucleotide repeat-containing gene 6A protein TNRC6A Tbio Non-IDG -2.03159 112.3 66