Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
decreased body length 1 | 101
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
improved glucose tolerance 1 | 79
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92

Disease

Carcinoma 5 | 11,493
osteosarcoma 3 | 7,950
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
Abnormality of the cranial nerves 1 | 7
Abnormality of the metaphyses 1 | 48
Acrorenal syndrome 1 | 1
Alcohol Withdrawal Seizures 1 | 2
Alcoholic Intoxication, Chronic 1 | 289
Aplasia/Hypoplasia of the skin 1 | 16
Atrial Fibrillation 1 | 124
Big calvaria 1 | 147
Breast Neoplasms 1 | 445
Bunion 1 | 26
Cerebral calcification 1 | 43
Chronic heart failure 1 | 46
Congenital Camptodactyly 1 | 40
Congenital Heart Defects 1 | 58
Congenital deafness 1 | 185
Cranial nerve abnormality 1 | 7
Craniofacial hyperostosis 1 | 11
Deafness 1 | 198
Defective tooth enamel 1 | 31
Delayed Puberty 1 | 97
Developmental regression 1 | 95
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Diphtheria 1 | 40
Disease Models, Animal 1 | 155
Dystrophic tooth enamel 1 | 31
Enamel abnormalities 1 | 31
Enlargement of craniofacial bones 1 | 11
Episcleritis 1 | 3
Exophthalmos 1 | 112
Fever 1 | 138
Flexion contracture - elbow 1 | 32
Frequent fractures 1 | 53
Gestational diabetes 1 | 26
Granuloma inguinale 1 | 3
Hallux Valgus 1 | 26
Hearing Loss 1 | 17
Hearing Loss, Partial 1 | 185
Heart Defects, Congenital 1 | 37
Hepatomegaly 1 | 285
Hepatosplenomegaly 1 | 22
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Histiocytosis 1 | 12
Huntington Disease 1 | 13
Hyperpigmentation 1 | 37
Hypertrichosis 1 | 46
Hypertrophy of craniofacial bones 1 | 11
Hypoplastic vertebral bodies 1 | 7
Imperforate anus 1 | 25
Increased fracture rate 1 | 53
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Irregular vertebral endplates 1 | 16
Isolated somatotropin deficiency 1 | 30
Late tooth eruption 1 | 61
Loss of developmental milestones 1 | 95
Lymphadenopathy 1 | 62
Mammary Neoplasms 1 | 425
Mental deterioration in childhood 1 | 95
Myocardial Perfusion Imaging Adjunct 1 | 25
Neurodevelopmental regression 1 | 95
Osteosclerosis 1 | 31
Otitis Media 1 | 52
Pancreatic Neoplasm 1 | 85
Pancreatic Neoplasms 1 | 85
Pertussis 1 | 20
Phenotypic variability 1 | 150
Platelet Aggregation Inhibition 1 | 22
Platyspondyly 1 | 56
Pneumonia 1 | 174
Prevention of Cerebral Thrombosis 1 | 29
Primary hypogonadism 1 | 37
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Rhinoscleroma 1 | 5
Rough bone trabeculation 1 | 11
Scleroderma 1 | 7
Scleroderma-like secondary cutaneous sclerosis 1 | 7
Sensorineural Hearing Loss (disorder) 1 | 284
Small testicle 1 | 75
Stiff skin 1 | 3
Systemic lupus erythematosus 1 | 194
Tetanus 1 | 68
Thick craniofacial bones 1 | 11
Varying degree of multiple fractures 1 | 53
Ventricular Septal Defects 1 | 119
hearing impairment 1 | 199

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Respiratory system 4 | 16,393

Target Family

Transporter 5 | 473

GO Function

nucleoside transmembrane trans... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Equilibrative nucleoside transporter 4 SLC29A4 Tchem Transporter -1.89372 80.8 214
Equilibrative nucleoside transporter 3 SLC29A3 Tbio Transporter -2.44355 273.3 75
Sodium/nucleoside cotransporter 1 SLC28A1 Tbio Transporter -1.94286 85.5 41
Equilibrative nucleoside transporter 2 SLC29A2 Tbio Transporter -2.12615 126.7 93
Equilibrative nucleoside transporter 1 SLC29A1 Tclin Transporter -2.61544 427.2 413