Development Level

Tbio 17 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 2 | 220
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryonic autopod pla... 1 | 2
abnormal facial morphology 1 | 17
abnormal placenta morphology 1 | 5
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 8 | 11,493
ependymoma 8 | 4,679
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
ovarian cancer 7 | 8,520
glioblastoma 6 | 5,792
atypical teratoid / rhabdoid tumor 5 | 5,112
group 3 medulloblastoma 5 | 4,104
interstitial cystitis 5 | 2,312
oligodendroglioma 5 | 2,850
tuberculosis 5 | 2,010
Breast cancer 4 | 3,578
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
lung cancer 4 | 4,740
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Primary ciliary dyskinesia 3 | 76
Reticular dysgenesis 3 | 7
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Kidney cancer 2 | 2,613
Pain disorder 2 | 15
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
Abdominal Pain 1 | 98
Abnormal ciliary motility 1 | 2
Amphetamine-Related Disorders 1 | 74
Anemia 1 | 365
Anterograde amnesia 1 | 3
Attention deficit hyperactivity disorder 1 | 278
Bone pain 1 | 42
Carcinoma, Hepatocellular 1 | 228
Ciliary Motility Disorders 1 | 38
Colorectal Neoplasms 1 | 243
Congenital myasthenic syndrome 1 | 25
Degenerative polyarthritis 1 | 115
Diarrhea 1 | 253
Endometriosis 1 | 540
Failure to gain weight 1 | 365
Fever 1 | 138
Ganglioneuroma 1 | 13
Gastrointestinal Stromal Tumors 1 | 48
Hemoglobin low 1 | 124
Hepatitis C 1 | 94
Hypertrophic Cardiomyopathy 1 | 117
Hypoxia 1 | 33
Isolated cases 1 | 72
Kartagener Syndrome 1 | 38
Liver carcinoma 1 | 240
Male infertility 1 | 206
Mental Depression 1 | 333
Multiple Sclerosis 1 | 540
Myocardial Ischemia 1 | 169
Myoclonus 1 | 74
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Neuroblastoma 1 | 80
Opsoclonus 1 | 5
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Pediatric failure to thrive 1 | 365
Prosopagnosia 1 | 4
Recurrent respiratory infections 1 | 141
Recurrent sinus disease 1 | 22
Recurrent sinusitis 1 | 22
Situs Inversus 1 | 65
Situs ambiguus 1 | 25
Substance-Related Disorders 1 | 115
Thrombophlebitis 1 | 19
Weight decreased 1 | 103
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
nail-patella syndrome 1 | 16
nephrosclerosis 1 | 333
non-small cell lung carcinoma 1 | 317
permanent atrial fibrillation 1 | 45
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 16 | 15,192

Target Family

Kinase 14 | 634
Enzyme 2 | 4,145
Non-IDG 2 | 12,091

GO Function

nucleoside diphosphate kinase ... 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate kinase isoenzyme 5 AK5 Tbio Kinase -1.83209 76.0 225
Thioredoxin domain-containing protein 6 NME9 Tbio Non-IDG -0.15719 1.86 110
Adenylate kinase 4, mitochondrial AK4 Tbio Kinase -1.83029 66.5 272
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113
Adenylate kinase isoenzyme 1 AK1 Tbio Kinase -2.37718 230.1 422
Thioredoxin domain-containing protein 3 NME8 Tbio Non-IDG -1.03981 11.2 79
Nucleoside diphosphate kinase, mitochondrial NME4 Tbio Kinase -1.75871 56.4 240
Nucleoside diphosphate kinase homolog 5 NME5 Tbio Kinase -0.86091 6.37 122
UMP-CMP kinase 2, mitochondrial CMPK2 Tbio Kinase -1.60739 42.5 79