Development Level

Tdark 109 | 6,588
Tbio 92 | 11,445
Tchem 8 | 1,598
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal testis morphology 2 | 43
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased circulating HDL chol... 2 | 80
increased total body fat amoun... 2 | 134
small testis 2 | 58
abnormal coat-hair pigmentatio... 1 | 64
abnormal esophagus morphology 1 | 5
abnormal heart morphology 1 | 162
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased lean body mass 1 | 172
male infertility 1 | 123
polysyndactyly 1 | 2
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
vertebral transformation 1 | 12

Disease

Carcinoma 106 | 11,493
osteosarcoma 79 | 7,950
ovarian cancer 79 | 8,520
medulloblastoma, large-cell 54 | 6,241
psoriasis 53 | 6,694
lung cancer 45 | 4,740
glioblastoma 43 | 5,792
group 3 medulloblastoma 42 | 4,104
ependymoma 34 | 4,679
atypical teratoid / rhabdoid tumor 31 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
Kidney cancer 26 | 2,613
malignant mesothelioma 26 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
Breast cancer 23 | 3,578
Pick disease 21 | 1,894
adult high grade glioma 21 | 3,801
subependymal giant cell astrocytoma 21 | 2,287
group 4 medulloblastoma 19 | 1,855
pituitary cancer 19 | 1,972
primitive neuroectodermal tumor 19 | 3,035
astrocytic glioma 17 | 2,597
oligodendroglioma 16 | 2,850
Cancer 15 | 2,499
interstitial cystitis 15 | 2,312
invasive ductal carcinoma 15 | 2,951
tuberculosis 15 | 2,010
Astrocytoma, Pilocytic 14 | 3,081
diabetes mellitus 13 | 1,728
lung carcinoma 13 | 2,843
colon cancer 11 | 1,478
pancreatic cancer 11 | 2,398
progressive supranuclear palsy 11 | 676
ulcerative colitis 11 | 1,819
Multiple myeloma 10 | 1,332
adrenocortical carcinoma 10 | 1,428
breast carcinoma 10 | 1,638
cystic fibrosis 10 | 1,696
juvenile dermatomyositis 10 | 1,187
non-small cell lung cancer 10 | 2,890
ductal carcinoma in situ 9 | 1,745
hepatocellular carcinoma 9 | 547
pediatric high grade glioma 9 | 1,064
Rheumatoid arthritis 8 | 1,191
Waldenstrons macroglobulinemia 8 | 765
acute myeloid leukemia 8 | 783
astrocytoma 8 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
dermatomyositis 7 | 966
non primary Sjogren syndrome sicca 7 | 891
primary Sjogren syndrome 7 | 735
tuberculosis and treatment for 6 months 7 | 409
Atopic dermatitis 6 | 952
acute quadriplegic myopathy 6 | 1,158
gastric cancer 6 | 459
gastric carcinoma 6 | 807
Intellectual disability 5 | 1,016
Melanoma 5 | 711
Obesity 5 | 678
Synovial sarcoma 5 | 25
cutaneous lupus erythematosus 5 | 1,057
facioscapulohumeral dystrophy 5 | 288
mucosa-associated lymphoid tissue lymphoma 5 | 484
primary pancreatic ductal adenocarcinoma 5 | 1,109
sonic hedgehog group medulloblastoma 5 | 467
spina bifida 5 | 1,074
Acquired metabolic disease 4 | 336
Amyotrophic lateral sclerosis 4 | 451
Glaucoma 4 | 239
Prostatic Neoplasms 4 | 495
Type 2 diabetes mellitus 4 | 272
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
chronic rhinosinusitis 4 | 512
fibroadenoma 4 | 559
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
lung adenocarcinoma 4 | 2,716
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
periodontitis 4 | 293
Allergic hypersensitivity disease 3 | 126
Alzheimer's disease 3 | 658
Asthma 3 | 385
Azoospermia 3 | 110
Cholestasis 3 | 155
Cockayne syndrome 3 | 60
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Gaucher disease type 1 3 | 180
Liver Cirrhosis, Experimental 3 | 769
Multiple Sclerosis 3 | 540
Sarcoma 3 | 62
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
Turner syndrome 3 | 28
active ulcerative colitis 3 | 764
aldosterone-producing adenoma 3 | 665
esophageal adenocarcinoma 3 | 737
head and neck cancer 3 | 271

Tissue

Endocrine System 173 | 18,159
Male tissues 166 | 17,142
Female tissues 165 | 17,400
Blood and immune system 164 | 16,909
Digestive Tract 163 | 17,369
Skin and soft tissues 163 | 17,230
Urinary Tract 160 | 16,678
Liver and Pancreas 159 | 16,750
Nervous System 159 | 16,725
Respiratory system 155 | 16,393
Cardiovascular System 145 | 15,192

Target Family

Non-IDG 108 | 12,091
Enzyme 66 | 4,145
Transcription Factor 27 | 1,400
Epigenetic 5 | 242
TF/Epigenetic 2 | 38
Ion Channel 1 | 344
Kinase 1 | 634

GO Function

nucleic acid binding 210 | 210
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Shadow of prion protein SPRN Tbio Non-IDG -2.49698 315.1 88
Ribonucleoprotein PTB-binding 2 RAVER2 Tdark Non-IDG -0.31876 3.20 38
G patch domain-containing protein 1 GPATCH1 Tdark Non-IDG 0.54 0.26 14
DBF4-type zinc finger-containing protein 2 ZDBF2 Tbio Non-IDG -0.82246 7.11 9
Zinc finger protein 839 ZNF839 Tdark Non-IDG 0.00000 55
Paraneoplastic antigen Ma3 PNMA3 Tbio Non-IDG -1.88721 71.6 105
Zinc finger protein 804B ZNF804B Tdark Non-IDG -0.10075 1.01 14
Zinc finger protein 608 ZNF608 Tdark Non-IDG -0.47998 2.60 62
Gypsy retrotransposon integrase-like protein 1 GIN1 Tdark Enzyme -1.99075 95.6 47
Endogenous retrovirus group K member 6 Pro protein ERVK-6 Tdark Enzyme 0.00000 0