Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
abnormal retinal blood vessel ... 1 | 26
abnormal urinary bladder morph... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased vertical activity 1 | 24
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 10 | 11,493
glioblastoma 9 | 5,792
osteosarcoma 8 | 7,950
Astrocytoma, Pilocytic 7 | 3,081
ependymoma 7 | 4,679
lung carcinoma 7 | 2,843
medulloblastoma, large-cell 7 | 6,241
Kidney cancer 6 | 2,613
atypical teratoid / rhabdoid tumor 6 | 5,112
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Autosomal recessive predisposition 5 | 1,442
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
Breast cancer 4 | 3,578
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Heart disease 4 | 306
Intellectual disability 4 | 1,016
Long QT syndrome 1 4 | 20
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Poor school performance 4 | 645
Romano-Ward Syndrome 4 | 12
Sudden infant death syndrome 4 | 32
dermatomyositis 4 | 966
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Cancer 3 | 2,499
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Cardiomegaly 3 | 116
Cardiomyopathy 3 | 116
Conduction disorder of the heart 3 | 79
Contracture 3 | 96
Contracture of joint 3 | 93
Creatine phosphokinase serum increased 3 | 110
Down syndrome 3 | 499
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Elevated creatine kinase 3 | 110
Epilepsy 3 | 792
Flexion contracture 3 | 93
Flexion contractures of joints 3 | 93
Heart conduction disease 3 | 83
Long QT syndrome 3 | 39
Myopathy 3 | 185
Status Epilepticus 3 | 98
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Atrial Fibrillation 2 | 124
Blepharoptosis 2 | 231
Cardiomyopathy, Dilated 2 | 83
Congenital pes cavus 2 | 88
Curvature of spine 2 | 282
Decreased tendon reflex 2 | 122
Difficulty walking 2 | 28
Dilated cardiomyopathy 2 | 56
Gowers sign 2 | 24
Gowers sign present 2 | 24
Hypertension 2 | 396
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Low Birth Weights 2 | 69
Malaria 2 | 160
Mental Depression 2 | 333
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Neoplasm Invasiveness 2 | 161
Neuropathy 2 | 261
Prenatal onset 2 | 139
Seizures 2 | 596
Small for gestational age (disorder) 2 | 69
Vascular disease 2 | 319
Ventricular Fibrillation 2 | 17
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
fibroadenoma 2 | 559
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Nervous System 12 | 16,725

Target Family

Non-IDG 9 | 12,091
Transporter 2 | 473
Enzyme 1 | 4,145
Ion Channel 1 | 344

GO Function

nitric-oxide synthase binding 13 | 13
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.13262 142.6 159
Dynamin-1 DNM1 Tbio Non-IDG -2.67692 450.0 464
Dynamin-3 DNM3 Tbio Non-IDG -1.43916 22.6 146
Dynamin-2 DNM2 Tchem Non-IDG -2.43547 282.5 143
Plasma membrane calcium-transporting ATPase 4 ATP2B4 Tbio Transporter -2.05889 122.8 121
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
HLA class II histocompatibility antigen gamma chain CD74 Tchem Non-IDG -2.44232 286.2 1032
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
Dystrophin DMD Tbio Non-IDG -3.50403 3129.8 363