Development Level

Tbio 11 | 11,651
Tclin 2 | 612

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal nail morphology 1 | 8
cataract 1 | 92
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
hypoactivity 1 | 132
increased circulating iron lev... 1 | 30
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 10 | 11,493
lung cancer 8 | 4,740
psoriasis 8 | 6,694
ovarian cancer 7 | 8,520
Kidney cancer 6 | 2,613
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
Breast cancer 5 | 3,578
adult high grade glioma 5 | 3,801
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
Astrocytoma, Pilocytic 4 | 3,081
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
cystic fibrosis 4 | 1,696
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
pediatric high grade glioma 4 | 1,064
Endometrial Neoplasms 3 | 55
Kallmann syndrome 3 | 33
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
non-small cell lung cancer 3 | 2,890
non-small cell lung carcinoma 3 | 317
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Adenocarcinoma 2 | 122
Anosmia 2 | 22
Anterior hypopituitarism 2 | 18
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Carcinoma, Non-Small-Cell Lung 2 | 107
Chronic obstructive pulmonary disease 2 | 184
Congenital hypoplasia of penis 2 | 176
Cryptorchidism 2 | 296
Delayed Puberty 2 | 97
Downward slant of palpebral fissure 2 | 158
Endometriosis 2 | 540
Heart Defects, Congenital 2 | 37
Hirschsprung Disease 2 | 31
Hirschsprung's disease 2 | 46
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Low-set, posteriorly rotated ears 2 | 110
Multiple Sclerosis 2 | 540
Muscle hypotonia 2 | 571
Neoplasm Metastasis 2 | 168
Neoplasms, Experimental 2 | 40
Neurodegenerative disease 2 | 414
Polycystic ovary syndrome 2 | 360
Precancerous Conditions 2 | 80
Rheumatoid arthritis 2 | 1,191
Small testicle 2 | 75
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
progressive supranuclear palsy 2 | 676
ulcerative colitis 2 | 1,819
Anophthalmos 1 | 13
Aplasia/Hypoplasia of the earlobes 1 | 10
Blastic phase chronic myeloid leukemia 1 | 58
Bone Diseases, Developmental 1 | 27
Bone disease 1 | 10
Brain Neoplasms 1 | 33
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic eosinophilic leukemia 1 | 11
Chronic phase chronic myeloid leukemia 1 | 45
Coats disease 1 | 13
Dermatofibrosarcoma protuberans 1 | 15
Endophthalmitis 1 | 12
Epilepsy, Temporal Lobe 1 | 23
Facial asymmetry 1 | 32
High pitched voice 1 | 23
Kuhnt-Junius degeneration 1 | 14
Learning Disorders 1 | 29
Macular holes 1 | 11
Memory Disorders 1 | 40
Metastasis from malignant tumor of colon 1 | 8
Musculoskeletal Abnormalities 1 | 6
Myelodysplastic/ Myeloproliferative Diseases associated with Platelet-derived Growth Factor Receptor 1 | 9
Neoplasms 1 | 63
POEMS syndrome 1 | 6
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Postnatal growth retardation 1 | 57
Sialolithiasis 1 | 2
Systemic mast cell disease 1 | 12
acute T cell leukemia 1 | 17

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 12 | 12,091
Kinase 1 | 634

GO Function

neuropilin binding 13 | 13
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Semaphorin-3C SEMA3C Tbio Non-IDG -1.95299 88.1 184
Semaphorin-3E SEMA3E Tbio Non-IDG -1.62878 48.9 219
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809
Paxillin PXN Tbio Non-IDG -2.99437 902.9 1251
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.51854 3418.5 1661
Semaphorin-7A SEMA7A Tbio Non-IDG -1.98241 103.5 272
Semaphorin-5A SEMA5A Tbio Non-IDG -1.82162 69.8 238
Semaphorin-3F SEMA3F Tbio Non-IDG -1.97011 94.5 125
Semaphorin-3D SEMA3D Tbio Non-IDG -1.67367 50.4 110
Semaphorin-3G SEMA3G Tbio Non-IDG -2.44351 256.6 86