Development Level

Tchem 9 | 1,598
Tclin 8 | 613
Tbio 2 | 11,445
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 4 | 126

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased vertical activity 1 | 208
enlarged heart 1 | 210
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 13 | 11,493
psoriasis 8 | 6,694
Alcoholic Intoxication, Chronic 6 | 289
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
osteosarcoma 6 | 7,950
Acromegaly 5 | 51
Adenoma 5 | 167
Cancer 5 | 2,499
Carcinoid syndrome 5 | 5
Cocaine Dependence 5 | 51
Depressive disorder 5 | 409
Diarrhea from Pancreatic VIPoma 5 | 5
Obesity 5 | 678
Pituitary adenoma 5 | 38
Status Epilepticus 5 | 98
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
ovarian cancer 5 | 8,520
Alcohol dependence 4 | 107
Astrocytoma, Pilocytic 4 | 3,081
Chronic Pain with Opioid Tolerance 4 | 5
Chronic pain 4 | 9
Epilepsy 4 | 792
Hypercortisolism 4 | 8
Mental Depression 4 | 333
Opiate dependence 4 | 29
Prevention of opioid abuse 4 | 5
Severe pain 4 | 11
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
Acute postoperative pain 3 | 6
Alcohol abuse 3 | 50
Alcoholism 3 | 45
Anxiety due to Cardiac Asthma 3 | 3
Cushing's syndrome 3 | 48
General anesthesia 3 | 53
Heroin dependence 3 | 30
Labor pain 3 | 4
Local anesthesia 3 | 40
Neuroendocrine Tumors 3 | 11
Opiate-Induced Respiratory Depression 3 | 4
Opioid dependence 3 | 4
Pain 3 | 103
Pain agnosia 3 | 104
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Poisoning by opiate analgesic drug 3 | 4
Schizophrenia 3 | 1,160
Seizures 3 | 596
Severe Pain with Opioid Tolerance 3 | 3
Substance Withdrawal Syndrome 3 | 55
Therapeutic opioid induced constipation 3 | 3
Allergic rhinitis 2 | 94
Anhedonia 2 | 27
Arrhythmias, Cardiac 2 | 19
Asthma 2 | 385
Bipolar Disorder 2 | 666
Cardiac Arrhythmia 2 | 103
Cocaine-Related Disorders 2 | 92
Common cold 2 | 67
Constipation 2 | 181
Depressive Disorder, Major 2 | 19
Eating disorder 2 | 26
Erythropoietic protoporphyria 2 | 15
Hypersomatotropic gigantism 2 | 2
Hypotension, Orthostatic 2 | 18
Irritable bowel syndrome with diarrhea 2 | 3
Major Depressive Disorder 2 | 301
Mood Disorders 2 | 184
Morphine dependence 2 | 16
Neonatal abstinence syndrome 2 | 11
Nonorganic psychosis 2 | 84
Psychotic Disorders 2 | 151
Sedation as Adjunct to Anesthesia 2 | 15
Substance-Related Disorders 2 | 115
Unipolar Depression 2 | 250
head and neck cancer 2 | 271
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
malignant mesothelioma 2 | 3,232
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
Alcoholic Intoxication 1 | 34
Cosyntropin preparation 1 | 2
Depression, Postpartum 1 | 7
Diagnostic Test for Secondary Adrenocortical Insufficiency 1 | 4
Exacerbation of multiple sclerosis 1 | 2
Fever 1 | 138
Gout 1 | 106
Hepatitis C 1 | 94
Hyperinsulinism 1 | 133
Metabolic syndrome X 1 | 52
Mucoepidermoid carcinoma 1 | 26
Neurodegeneration with brain iron accumulation 5 1 | 9
Pruritus 1 | 58
Salmonellosis 1 | 42
Stevens-Johnson syndrome 1 | 92
West Syndrome 1 | 28

Tissue

Endocrine System 18 | 18,159
Nervous System 18 | 16,725
Female tissues 16 | 17,400
Male tissues 16 | 17,142
Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Liver and Pancreas 14 | 16,750
Skin and soft tissues 14 | 17,230
Respiratory system 13 | 16,393
Urinary Tract 13 | 16,678
Cardiovascular System 10 | 15,192

Target Family

GPCR 20 | 408

GO Function

neuropeptide binding 20 | 20
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
Melanocortin receptor 3 MC3R Tchem GPCR -2.65556 445.3 202
Neuropeptides B/W receptor type 1 NPBWR1 Tchem GPCR -1.37250 19.8 162
Neuropeptides B/W receptor type 2 NPBWR2 Tbio GPCR -1.17662 9.08 68
G-protein coupled receptor 1 GPR1 Tbio GPCR -1.63825 37.7 144
Somatostatin receptor type 5 SSTR5 Tclin GPCR -2.10658 120.8 191
Somatostatin receptor type 3 SSTR3 Tclin GPCR -1.89900 68.6 106
Somatostatin receptor type 4 SSTR4 Tclin GPCR -1.72615 44.8 147