Development Level

Tbio 11 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal locomotor behavior 1 | 24
aorta stenosis 1 | 2
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
enlarged liver 1 | 2
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46

Disease

Carcinoma 12 | 11,493
osteosarcoma 9 | 7,950
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
atypical teratoid / rhabdoid tumor 7 | 5,112
Autistic Disorder 6 | 364
glioblastoma 6 | 5,792
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pediatric high grade glioma 5 | 1,064
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
colon cancer 4 | 1,478
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
Asperger syndrome 3 | 37
Breast cancer 3 | 3,578
Intellectual disability 3 | 1,016
Schizophrenia 3 | 1,160
ductal carcinoma in situ 3 | 1,745
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
tuberculosis 3 | 2,010
Atypical autism 2 | 26
Autism spectrum disorder 2 | 101
Duchenne muscular dystrophy 2 | 601
Griscelli syndrome 2 | 24
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
fibroadenoma 2 | 559
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group B ependymoma 2 | 416
Absent speech 1 | 43
Alcoholic Intoxication, Chronic 1 | 289
Animal Mammary Neoplasms 1 | 136
Autism Spectrum Disorders 1 | 75
Axial hypotonia 1 | 46
Broad forehead 1 | 59
Broad nasal tip 1 | 28
Cerebral atrophy 1 | 178
Chediak-Higashi syndrome 1 | 26
Chondrodysplasia punctata 1 | 41
Congenital nystagmus 1 | 26
Convex nasal bridge 1 | 57
Diarrhea 1 | 253
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
FG syndrome 1 | 16
Global developmental delay, severe 1 | 47
Globe of eye large 1 | 20
Hepatitis B 1 | 108
Hyperreflexia 1 | 209
Hypohidrosis 1 | 34
Insulin Resistance 1 | 72
Isolated cleft palate 1 | 4
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Liver Cirrhosis 1 | 181
Liver cancer 1 | 604
Low Vision 1 | 174
Lung Neoplasms 1 | 232
Macrotia 1 | 87
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Microcephaly 1 | 166
Moderate mental retardation (I.Q. 35-49) 1 | 28
Muscle Spasticity 1 | 195
Muscle Weakness 1 | 170
Myopia 1 | 176
Neurodevelopmental Disorders 1 | 70
Ocular albinism 1 | 26
Prominent nasal bridge 1 | 57
Sensorineural Hearing Loss (disorder) 1 | 284
Severe psychomotor retardation 1 | 47
Visual Impairment 1 | 174
Weight decreased 1 | 103
X-linked cerebral adrenoleukodystrophy 1 | 116
X-linked dominant 1 | 57
active ulcerative colitis 1 | 764
adrenocortical adenoma 1 | 131
chronic kidney disease 1 | 90
fascioscapulohumeral muscular dystrophy 1 | 100
nonverbal 1 | 43
posterior fossa group A ependymoma 1 | 468
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Enzyme 6 | 4,145
Non-IDG 5 | 12,091
Kinase 1 | 634

GO Function

neurexin family protein bindin... 12 | 12
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carboxypeptidase E CPE Tbio Enzyme -3.01460 1019.8 229
Synaptotagmin-like protein 2 SYTL2 Tbio Non-IDG -1.27949 19.5 60
Synaptotagmin-like protein 3 SYTL3 Tbio Non-IDG -1.02669 10.4 84
Neuroligin-2 NLGN2 Tbio Enzyme -1.71616 50.4 77
Synaptotagmin-like protein 4 SYTL4 Tbio Non-IDG -1.22383 18.7 112
Peripheral plasma membrane protein CASK CASK Tchem Kinase -2.12241 130.2 227
Neuroligin-1 NLGN1 Tbio Enzyme -1.96626 95.1 225
Neuroligin-4, X-linked NLGN4X Tbio Enzyme -1.77739 57.8 135
Neuroligin-3 NLGN3 Tbio Enzyme -1.86262 71.5 179
Leucine-rich repeat transmembrane neuronal protein 2 LRRTM2 Tbio Non-IDG -0.86860 8.30 115