Development Level

Tbio 1 | 11,445
Tchem 1 | 1,598

Disease

Arthrogryposis 2 | 54
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Duchenne muscular dystrophy 2 | 601
Hydronephrosis 2 | 89
Polyhydramnios 2 | 108
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ANONYCHIA 1 | 20
Abdomen distended 1 | 43
Accessory kidney 1 | 5
Akinesia 1 | 13
Alopecia areata 1 | 41
Aplasia Cutis Congenita 1 | 14
Atrophic scar 1 | 18
Axillary pterygia 1 | 6
Barrett's esophagus 1 | 182
Bipolar Disorder 1 | 666
Blastic phase chronic myeloid leukemia 1 | 58
Breast Neoplasms 1 | 445
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic phase chronic myeloid leukemia 1 | 45
Common variable immunodeficiency 1 | 101
Congenital scar 1 | 13
Death in early childhood 1 | 82
Death in infancy 1 | 82
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Diarrhea, intractable 1 | 6
Disease Progression 1 | 136
Down syndrome 1 | 499
Dysplasia of tooth enamel 1 | 35
Dystrophia unguium 1 | 53
Ectropion 1 | 38
Edema 1 | 81
Elevated maternal serum alpha-fetoprotein 1 | 4
Epidermolysis bullosa 1 | 21
Esophageal atresia 1 | 43
Fragile skin 1 | 18
Gallbladder Neoplasms 1 | 10
HER2-positive carcinoma of breast 1 | 21
Intestinal atresia 1 | 12
Junctional split 1 | 6
Lung Neoplasms 1 | 232
Major Depressive Disorder 1 | 301
Mammary Neoplasms 1 | 425
Mental Depression 1 | 333
Milium Cyst 1 | 16
Nail dysplasia 1 | 52
Nausea and vomiting 1 | 97
Neoplasm Metastasis 1 | 168
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Oral mucosal blistering 1 | 10
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pick disease 1 | 1,894
Prenatal onset 1 | 139
Prostate cancer 1 | 175
RENAL ADYSPLASIA 1 | 25
Recurrence 1 | 33
Recurrent skin infections 1 | 21
Reduced fetal movement 1 | 51
Renal dysplasia 1 | 28
Respiratory Failure 1 | 104
Severe myopia 1 | 22
Skeletal muscle atrophy 1 | 139
Thin dental enamel 1 | 35
Type 1 diabetes mellitus 1 | 109
Unipolar Depression 1 | 250
Ureterocele 1 | 14
Urethral Stricture 1 | 18
Urogenital Abnormalities 1 | 9
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
fibroadenoma 1 | 559
gallbladder neoplasm 1 | 10
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
juvenile dermatomyositis 1 | 1,187
muscle degeneration 1 | 139
nasopharyngeal carcinoma 1 | 1,058
non-small cell lung cancer 1 | 2,890
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Kinase 1 | 634
Non-IDG 1 | 12,091

GO Function

neuregulin binding 2 | 2
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-6 ITGA6 Tbio Non-IDG -2.30127 180.4 944
Receptor tyrosine-protein kinase erbB-3 ERBB3 Tchem Kinase -2.97833 870.3 1652