Development Level

Tbio 5 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
decreased circulating amylase ... 1 | 28
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
enlarged lymph nodes 1 | 37
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
ovarian cancer 4 | 8,520
Autosomal recessive predisposition 3 | 1,442
lung cancer 3 | 4,740
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Cardiomyopathy 2 | 116
Cardiomyopathy, Hypertrophic 2 | 24
Cardiomyopathy, Hypertrophic, Familial 2 | 9
Dilated cardiomyopathy 2 | 56
Hypertrophic Cardiomyopathy 2 | 117
Left ventricular noncompaction 2 | 26
Myopathy 2 | 185
Primary cutaneous amyloidosis 2 | 29
Recurrent respiratory infections 2 | 141
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Acquired scoliosis 1 | 281
Animal Mammary Neoplasms 1 | 136
Astigmatism 1 | 54
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cardiomyopathy, Dilated 1 | 83
Cardiomyopathy, Familial Hypertrophic, 4 1 | 1
Cardiovascular system disease 1 | 246
Congenital Fiber Type Disproportion 1 | 7
Congenital myopathy with fiber type disproportion 1 | 9
Congestive heart failure 1 | 113
Curvature of spine 1 | 282
Death, Sudden, Cardiac 1 | 5
Decreased to absent deep tendon reflexes 1 | 42
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Disease Models, Animal 1 | 155
Distal arthrogryposis 1 | 42
Down syndrome 1 | 499
Epidermodysplasia verruciformis 1 | 21
Familial isolated dilated cardiomyopathy 1 | 41
Gastrointestinal stromal tumor 1 | 62
Glycogen storage disease IV 1 | 6
Gynecomastia 1 | 64
Hamman-Rich syndrome 1 | 34
Heart disease 1 | 306
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hyperactive behavior 1 | 91
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Idiopathic hypogonadotropic hypogonadism 1 | 21
Immunologic Deficiency Syndromes 1 | 113
Infantile onset 1 | 238
Kidney Neoplasm 1 | 29
Kidney Neoplasms 1 | 37
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Lipodystrophy 1 | 40
Liver Cirrhosis, Experimental 1 | 769
Lymphopenia 1 | 67
Mammary Neoplasms, Animal 1 | 136
Melanoma 1 | 711
Multiple acyl-CoA dehydrogenase deficiency 1 | 25
Muscle Weakness 1 | 170
Muscular Diseases 1 | 27
Muscular atrophy 1 | 71
Myopia 1 | 176
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Neoplasms, Experimental 1 | 40
Neurilemmoma 1 | 23
Pancreatic Neoplasms 1 | 85
Pancreatic Neuroendocrine Tumor 1 | 45
Pectus excavatum 1 | 100
Phenotypic variability 1 | 150
Pityriasis versicolor 1 | 19
Primary physiologic amenorrhea 1 | 55
Renal Cell Carcinoma 1 | 214
Severe combined immunodeficiency 1 | 51
Skin cancer 1 | 469
Small testicle 1 | 75
Sparse axillary hair 1 | 28
Sparse pubic hair 1 | 31
Sudden Cardiac Death 1 | 29
Tachycardia, Ventricular 1 | 22
Waldenstrons macroglobulinemia 1 | 765
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
chronic kidney disease 1 | 90
fibroadenoma 1 | 559
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Respiratory system 6 | 16,393
Nervous System 5 | 16,725

Target Family

Non-IDG 5 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

myosin heavy chain binding 7 | 7
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
AMP deaminase 1 AMPD1 Tchem Enzyme -2.35602 227.5 148
Myosin regulatory light chain 12B MYL12A Tbio Non-IDG -1.48844 28.9 135
Tyrosine-protein kinase receptor UFO AXL Tchem Kinase -2.69969 528.1 756
Myosin-binding protein C, cardiac-type MYBPC3 Tbio Non-IDG -2.45618 287.6 139
Protein naked cuticle homolog 2 NKD2 Tbio Non-IDG -1.29843 19.7 121
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform MYL2 Tbio Non-IDG -2.23022 155.8 222
Coronin-1A CORO1A Tbio Non-IDG -2.12473 140.2 312