Development Level

Tbio 15 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal embryo size 2 | 220
preweaning lethality, complete... 2 | 979
abnormal embryo turning 1 | 31
abnormal sleep behavior 1 | 70
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
increased prepulse inhibition 1 | 32
persistence of hyaloid vascula... 1 | 33

Disease

medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
atypical teratoid / rhabdoid tumor 9 | 5,112
adult high grade glioma 8 | 3,801
glioblastoma 8 | 5,792
ovarian cancer 8 | 8,520
Pick disease 7 | 1,894
ependymoma 7 | 4,679
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Astrocytoma, Pilocytic 6 | 3,081
astrocytic glioma 6 | 2,597
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
Carcinoma 5 | 11,493
Griscelli syndrome 5 | 24
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
Multiple myeloma 4 | 1,332
ductal carcinoma in situ 4 | 1,745
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
pituitary cancer 4 | 1,972
Cancer 3 | 2,499
Choroideremia 3 | 16
Parkinson's disease 3 | 392
astrocytoma 3 | 1,146
facioscapulohumeral dystrophy 3 | 288
hepatocellular carcinoma 3 | 547
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Breast cancer 2 | 3,578
Epilepsy 2 | 792
Hyperlipidemia 2 | 43
Lipid metabolism disorder 2 | 114
Muscle Spasticity 2 | 195
Neurodegenerative disease 2 | 414
Oculocerebrorenal syndrome 2 | 29
Rheumatoid arthritis 2 | 1,191
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
gastric carcinoma 2 | 807
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
Anxiety 1 | 136
Anxiety disease 1 | 113
Aphasia 1 | 26
Apraxia 1 | 26
Arterial tortuosity syndrome 1 | 7
Autosomal recessive nonsyndromic deafness 63 1 | 10
COPD 1 | 118
Chediak-Higashi syndrome 1 | 26
Chlamydia 1 | 21
Chloracne 1 | 32
Ciliopathy 1 | 71
Death in childhood 1 | 14
Dyspnea 1 | 76
Essential tremor 1 | 28
Ewing sarcoma 1 | 25
Fatty liver disease 1 | 103
Griscelli syndrome type 2 1 | 12
HIV Infections 1 | 102
Hermansky-Pudlak syndrome 1 | 42
Hypopigmentation disorder 1 | 25
Immunologic Deficiency Syndromes 1 | 113
Increased susceptibility to bacterial infections 1 | 42
Juvenile amyotrophic lateral sclerosis 1 | 4
Lateral sclerosis 1 | 15
Lymphadenopathy 1 | 62
Mevalonic aciduria 1 | 16
Microvillus inclusion disease 1 | 8
Mood swings 1 | 77
Muscle Cramp 1 | 55
Muscle atrophy, proximal 1 | 11
Muscular fasciculation 1 | 22
Myoepithelioma 1 | 13
Myxoid liposarcoma 1 | 6
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neutrophil count decreased 1 | 47
Oculocutaneous albinism 1 | 29
Pain 1 | 103
Paralysed 1 | 42
Pick's disease 1 | 15
Platelet storage pool deficiency 1 | 21
Prone to bacterial infection 1 | 42
Recurrent bacterial infection 1 | 42
Static Tremor 1 | 21
Varicose veins 1 | 20
non-small cell lung carcinoma 1 | 317

Tissue

Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Blood and immune system 16 | 16,909
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Cardiovascular System 12 | 15,192

Target Family

Enzyme 15 | 4,145
Non-IDG 2 | 12,091

GO Function

myosin V binding 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-3D RAB3D Tbio Enzyme -2.56190 342.2 106
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.47825 30.5 103
Ras-related protein Rab-8A RAB8A Tbio Enzyme -2.22872 157.9 190
Ras-related protein Rab-10 RAB10 Tbio Enzyme -1.62208 41.1 164
Ras-related protein Rab-3C RAB3C Tbio Enzyme -1.05905 11.2 90
Ras-related protein Rab-25 RAB25 Tbio Enzyme -1.79595 62.7 212
Ras-related protein Rab-3B RAB3B Tbio Enzyme -1.38932 26.8 121
Ras-related protein Rab-6A RAB6A Tbio Enzyme -2.09488 134.5 207
Ras-related protein Rab-27A RAB27A Tchem Enzyme -2.30319 204.9 308