Development Level

Tbio 35 | 10,625
Tdark 10 | 7,003
Tchem 3 | 1,890

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal sleep behavior 3 | 63
convulsive seizures 2 | 11
decreased lean body mass 2 | 195
decreased startle reflex 2 | 48
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal craniofacial morpholo... 1 | 12
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal forebrain morphology 1 | 4
abnormal motor coordination/ b... 1 | 4
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal tail morphology 1 | 17
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
corneal opacity 1 | 25
cyanosis 1 | 6
decreased Ly6C low monocyte nu... 1 | 23
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased effector memory CD4-... 1 | 6
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased total body fat amoun... 1 | 186
decreased urine creatinine lev... 1 | 2
decreased vertical activity 1 | 22
fused cornea and lens 1 | 4
fused phalanges 1 | 1
hemorrhage 1 | 12
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
increased CD8-positive, alpha-... 1 | 11
increased Ly6C high monocyte n... 1 | 12
increased circulating alkaline... 1 | 119
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
persistence of hyaloid vascula... 1 | 22

Disease

ovarian cancer 24 | 8,484
Carcinoma 22 | 2,147
osteosarcoma 21 | 7,933
psoriasis 21 | 6,685
glioblastoma 17 | 5,572
atypical teratoid / rhabdoid tumor 16 | 4,369
lung cancer 15 | 4,466
malignant mesothelioma 14 | 3,162
medulloblastoma, large-cell 14 | 6,234
non-small cell lung cancer 13 | 2,798
lung carcinoma 12 | 2,844
pilocytic astrocytoma 11 | 3,086
primitive neuroectodermal tumor 11 | 3,031
Breast cancer 10 | 3,094
pediatric high grade glioma 10 | 2,712
ependymoma 9 | 2,514
invasive ductal carcinoma 9 | 2,950
oligodendroglioma 9 | 2,849
posterior fossa group B ependymoma 9 | 1,530
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
Pick disease 6 | 1,893
Sensorineural hearing loss 6 | 107
acute quadriplegic myopathy 6 | 1,157
adult high grade glioma 6 | 2,148
diabetes mellitus 6 | 1,663
lung adenocarcinoma 6 | 2,713
nasopharyngeal carcinoma 6 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287
Paraplegia 5 | 71
astrocytic glioma 5 | 2,241
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
cutaneous lupus erythematosus 5 | 1,056
group 4 medulloblastoma 5 | 1,875
interstitial cystitis 5 | 2,299
medulloblastoma 5 | 1,524
progressive supranuclear palsy 5 | 674
spina bifida 5 | 1,064
Atopic dermatitis 4 | 944
Neurodegenerative disease 4 | 383
Nonsyndromic deafness 4 | 121
Situs Inversus 4 | 48
adrenocortical carcinoma 4 | 1,427
atypical teratoid/rhabdoid tumor 4 | 1,095
pancreatic cancer 4 | 2,300
Cardiomyopathy 3 | 110
Cardiovascular system disease 3 | 194
IGA Glomerulonephritis 3 | 454
Multiple myeloma 3 | 1,327
acute myeloid leukemia 3 | 780
chronic rhinosinusitis 3 | 512
dermatomyositis 3 | 933
facioscapulohumeral dystrophy 3 | 286
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis 3 | 1,557
ulcerative colitis 3 | 2,087
AMYOTROPHIC LATERAL SCLEROSIS 1 2 | 49
Amyotrophic Lateral Sclerosis 2 | 431
Asphyxiating thoracic dystrophy 2 | 32
Benign glioma 2 | 2
Cancer 2 | 2,346
Down syndrome 2 | 548
Endometriosis 2 | 535
Kartagener Syndrome 2 | 32
Left ventricular noncompaction 2 | 23
Leukemia 2 | 88
Neuropathy 2 | 210
Peripheral Neuropathy 2 | 303
Polydactyly 2 | 93
Primary ciliary dyskinesia 2 | 73
Rheumatoid Arthritis 2 | 1,160
Substance-Related Disorders 2 | 114
Usher syndrome 2 | 34
chronic lymphosyte leukemia 2 | 232
gastric carcinoma 2 | 832
hepatocellular carcinoma 2 | 532
hereditary spastic paraplegia 2 | 313
interstitial lung disease 2 | 291
juvenile dermatomyositis 2 | 1,189
non diabetic and post-ischemic heart failure 2 | 200
tuberculosis and treatment for 6 months 2 | 686
Acute monocytic leukemia 1 | 11
Aortic aneurysm 1 | 34
Asperger syndrome 1 | 35
Cardiomyopathy, Hypertrophic, Familial 1 | 21
Fanconi syndrome 1 | 14
Intracranial aneurysm 1 | 20
Keloid 1 | 34
Kidney cancer 1 | 118
Mood Disorders 1 | 3
Myotonic dystrophy type 1 1 | 16
Sensenbrenner syndrome 1 | 15
Short Rib-Polydactyly Syndrome 1 | 2

Tissue

Blood and immune system 46 | 17,995
Cardiovascular System 46 | 17,958
Digestive Tract 46 | 18,473
Endocrine System 46 | 18,512
Female tissues 46 | 18,647
Liver and Pancreas 46 | 18,136
Male tissues 46 | 17,969
Nervous System 46 | 18,561
Respiratory system 46 | 17,484
Skin and soft tissues 46 | 18,115
Urinary Tract 46 | 18,444

Target Family

Non-IDG 46 | 11,971
Enzyme 1 | 4,146
Kinase 1 | 634

GO Function

motor activity 48 | 48
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Myosin light chain 6B MYL6B Tdark Non-IDG -0.43175 2.57 113
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.32941 210.3 40
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Tctex1 domain-containing protein 3 TCTE3 Tdark Non-IDG -0.56557 4.53 21
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.59494 38.2 10
Dynein light chain Tctex-type 3 DYNLT3 Tbio Non-IDG -0.82512 6.34 52
Dynein heavy chain 9, axonemal DNAH9 Tbio Non-IDG -1.47466 30.0 30
Unconventional myosin-XVI MYO16 Tbio Non-IDG -0.79284 6.35 32
Kinesin-like protein KIF18B KIF18B Tdark Non-IDG -0.58358 4.73 17