Development Level

Tbio 15 | 10,625
Tchem 11 | 1,890
Tclin 6 | 602
Tdark 4 | 7,003

IMPC Term

abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal neural tube closure 1 | 37
abnormal tail bud morphology 1 | 6
abnormal vitreous body morphol... 1 | 7
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 107
persistence of hyaloid vascula... 1 | 22
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 20 | 6,685
osteosarcoma 15 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
lung cancer 13 | 4,466
Cancer 12 | 2,346
medulloblastoma, large-cell 12 | 6,234
ovarian cancer 12 | 8,484
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
non-small cell lung cancer 11 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
interstitial cystitis 10 | 2,299
Prostatic Neoplasms 9 | 471
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
lung carcinoma 9 | 2,844
tuberculosis 8 | 1,557
Breast cancer 7 | 3,094
Liver disease 7 | 219
glioblastoma 7 | 5,572
lung adenocarcinoma 7 | 2,713
Hypertension 6 | 287
adrenocortical carcinoma 6 | 1,427
cutaneous lupus erythematosus 6 | 1,056
cystic fibrosis 6 | 1,665
diabetes mellitus 6 | 1,663
pancreatic cancer 6 | 2,300
posterior fossa group A ependymoma 6 | 1,511
atypical teratoid / rhabdoid tumor 5 | 4,369
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
malignant mesothelioma 5 | 3,162
oligodendroglioma 5 | 2,849
pilocytic astrocytoma 5 | 3,086
primitive neuroectodermal tumor 5 | 3,031
Adverse reaction to drug 4 | 54
Drug-Induced Liver Injury 4 | 118
Human immunodeficiency virus infection 4 | 6
Lung Neoplasms 4 | 171
Mammary Neoplasms 4 | 410
Peripheral Neuropathy 4 | 303
Schizophrenia 4 | 501
adult high grade glioma 4 | 2,148
chronic rhinosinusitis 4 | 512
ductal carcinoma in situ 4 | 1,745
mucosa-associated lymphoid tissue lymphoma 4 | 480
pituitary cancer 4 | 1,972
Acute kidney injury 3 | 65
Atrial Fibrillation 3 | 110
Cardiomegaly 3 | 66
Epilepsy 3 | 346
Malaria 3 | 140
Pick disease 3 | 1,893
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 42
Rheumatoid Arthritis 3 | 1,160
adrenocortical adenoma 3 | 134
breast carcinoma 3 | 1,614
ependymoma 3 | 2,514
gastric carcinoma 3 | 832
invasive ductal carcinoma 3 | 2,950
nephrosclerosis 3 | 329
non diabetic and post-ischemic heart failure 3 | 200
pediatric high grade glioma 3 | 2,712
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482
substance-related disorder 3 | 105
Atopic dermatitis 2 | 944
Autoimmune hepatitis 2 | 13
Cerebrovascular disease 2 | 231
Chronic Obstructive Airway Disease 2 | 47
Colorectal Neoplasms 2 | 217
Contact Dermatitis 2 | 80
Coronary artery disease 2 | 240
Delusional disorder 2 | 10
Drug Eruptions 2 | 18
Drug allergy 2 | 36
Endometriosis 2 | 535
Essential Hypertension 2 | 82
Hepatitis C 2 | 90
Kidney Diseases 2 | 86
Liver Cirrhosis, Experimental 2 | 108
Liver Neoplasms, Experimental 2 | 48
Liver carcinoma 2 | 217
Major Depressive Disorder 2 | 106
Melanoma 2 | 261
Osteonecrosis 2 | 25
Pain agnosia 2 | 99
Parkinson Disease 2 | 102
Spontaneous abortion 2 | 108
Squamous cell carcinoma 2 | 94
active Crohn's disease 2 | 918
aldosterone-producing adenoma 2 | 664
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
esophageal adenocarcinoma 2 | 737
gliosarcoma 2 | 19
head and neck cancer 2 | 270
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
nervous system disorder 2 | 53
periodontitis 2 | 269
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 2,087

Tissue

Blood and immune system 35 | 17,995
Cardiovascular System 35 | 17,958
Digestive Tract 35 | 18,473
Endocrine System 35 | 18,512
Female tissues 35 | 18,647
Nervous System 35 | 18,561
Skin and soft tissues 35 | 18,115
Urinary Tract 35 | 18,444
Liver and Pancreas 34 | 18,136
Respiratory system 34 | 17,484
Male tissues 33 | 17,969

Target Family

Non-IDG 19 | 11,971
Enzyme 17 | 4,146

GO Function

monooxygenase activity 36 | 36
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FAD-dependent oxidoreductase domain-containing protein 2 FOXRED2 Tdark Enzyme -0.17609 2.34 58
Cytochrome P450 4V2 CYP4V2 Tbio Non-IDG -2.66290 481.8 87
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -1.98060 100.6 25
Thromboxane-A synthase TBXAS1 Tchem Enzyme -3.06668 1228.9 241
Cytochrome P450 2J2 CYP2J2 Tchem Non-IDG -2.03738 133.3 162
Tyrosinase TYR Tclin Enzyme -3.28004 1897.3 412
Cytochrome P450 4A22 CYP4A22 Tbio Non-IDG -0.91632 6.79 68
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial COQ6 Tbio Enzyme -1.19166 18.1 82
Phylloquinone omega-hydroxylase CYP4F11 CYP4F11 Tbio Enzyme -0.62468 5.23 82
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.52997 3553.5 340