Development Level

Tbio 41 | 10,625
Tdark 15 | 7,003
Tchem 11 | 1,890

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 4 | 260
abnormal behavioral response t... 2 | 52
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
increased fasted circulating g... 2 | 68
increased lean body mass 2 | 107
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal lens morphology 1 | 73
abnormal limb morphology 1 | 7
abnormal outer ear morphology 1 | 1
abnormal sleep behavior 1 | 63
absent pinna reflex 1 | 21
cyanosis 1 | 6
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased mean corpuscular hem... 1 | 34
decreased red blood cell distr... 1 | 11
decreased startle reflex 1 | 48
hemorrhage 1 | 12
increased bone mineral content 1 | 92
increased circulating chloride... 1 | 43
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 33 | 8,484
osteosarcoma 32 | 7,933
glioblastoma 28 | 5,572
medulloblastoma, large-cell 27 | 6,234
Carcinoma 26 | 2,147
psoriasis 25 | 6,685
atypical teratoid / rhabdoid tumor 24 | 4,369
lung cancer 23 | 4,466
malignant mesothelioma 21 | 3,162
posterior fossa group B ependymoma 21 | 1,530
pediatric high grade glioma 20 | 2,712
Breast cancer 19 | 3,094
nasopharyngeal carcinoma 18 | 1,056
non-small cell lung cancer 18 | 2,798
group 3 medulloblastoma 17 | 2,254
pilocytic astrocytoma 17 | 3,086
primitive neuroectodermal tumor 16 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
invasive ductal carcinoma 14 | 2,950
lung adenocarcinoma 14 | 2,713
lung carcinoma 14 | 2,844
chronic rhinosinusitis 13 | 512
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
adrenocortical carcinoma 12 | 1,427
Endometriosis 11 | 535
ductal carcinoma in situ 11 | 1,745
oligodendroglioma 11 | 2,849
breast carcinoma 10 | 1,614
Primary ciliary dyskinesia 9 | 73
colon cancer 9 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
Atopic dermatitis 8 | 944
pituitary cancer 8 | 1,972
posterior fossa group A ependymoma 8 | 1,511
IGA Glomerulonephritis 7 | 454
pancreatic cancer 7 | 2,300
subependymal giant cell astrocytoma 7 | 2,287
Kidney cancer 6 | 118
Pick disease 6 | 1,893
adult high grade glioma 6 | 2,148
astrocytic glioma 6 | 2,241
astrocytoma 6 | 1,493
fibroadenoma 6 | 557
group 4 medulloblastoma 6 | 1,875
Intellectual disability 5 | 573
Microcephaly 5 | 149
Neurodegenerative disease 5 | 383
Neuropathy 5 | 210
Paraplegia 5 | 71
Situs Inversus 5 | 48
atypical teratoid/rhabdoid tumor 5 | 1,095
ependymoma 5 | 2,514
interstitial cystitis 5 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
sonic hedgehog group medulloblastoma 5 | 1,482
ulcerative colitis 5 | 2,087
Cancer 4 | 2,346
Kartagener Syndrome 4 | 32
Male infertility 4 | 170
cutaneous lupus erythematosus 4 | 1,056
non-small cell lung carcinoma 4 | 413
spina bifida 4 | 1,064
Amyotrophic Lateral Sclerosis 3 | 431
Craniopharyngioma 3 | 13
Hydrolethalus syndrome 3 | 128
Malformations of Cortical Development 3 | 11
Obesity 3 | 616
Polydactyly 3 | 93
cystic fibrosis and chronic rhinosinusitis 3 | 213
diabetes mellitus 3 | 1,663
juvenile dermatomyositis 3 | 1,189
medulloblastoma 3 | 1,524
primary Sjogren syndrome 3 | 789
progressive supranuclear palsy 3 | 674
Asphyxiating thoracic dystrophy 2 | 32
Bardet-Biedl Syndrome 2 | 40
Bronchiectasis 2 | 29
Cardiovascular system disease 2 | 194
Charcot-Marie-Tooth disease 2 | 74
Ciliopathy 2 | 57
Congenital fibrosis of the extraocular muscles 2 | 11
Infertility 2 | 163
Liver cancer 2 | 31
Multiple myeloma 2 | 1,327
Nonepidermolytic palmoplantar keratoderma 2 | 11
Pallister-Hall syndrome 2 | 11
Peripheral Neuropathy 2 | 303
Progressive muscular atrophy 2 | 6
Seckel syndrome 2 | 34
Weight Gain 2 | 87
acute quadriplegic myopathy 2 | 1,157
cystic fibrosis 2 | 1,665
dermatomyositis 2 | 933
facioscapulohumeral dystrophy 2 | 286
hereditary spastic paraplegia 2 | 313
inflammatory breast cancer 2 | 404
periodontitis 2 | 269
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis 2 | 1,557
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 66 | 17,995
Cardiovascular System 66 | 17,958
Digestive Tract 66 | 18,473
Endocrine System 66 | 18,512
Female tissues 66 | 18,647
Liver and Pancreas 66 | 18,136
Male tissues 66 | 17,969
Nervous System 66 | 18,561
Skin and soft tissues 66 | 18,115
Urinary Tract 66 | 18,444
Respiratory system 65 | 17,484

Target Family

Non-IDG 67 | 11,971

GO Function

microtubule motor activity 67 | 67
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Kinesin-like protein KIFC3 KIFC3 Tchem Non-IDG -1.08696 12.5 48
Dynein heavy chain 14, axonemal DNAH14 Tdark Non-IDG -0.16914 1.36 38
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.33400 20.0 84
Structural maintenance of chromosomes protein 3 SMC3 Tbio Non-IDG -2.05162 104.9 234
Kinesin-like protein KIF21B KIF21B Tbio Non-IDG -0.94345 9.49 31
Kinesin light chain 2 KLC2 Tbio Non-IDG -0.68225 4.64 136
Dynein heavy chain 12, axonemal DNAH12 Tbio Non-IDG -1.21446 17.7 26
Dynein heavy chain 10, axonemal DNAH10 Tdark Non-IDG -0.44150 2.57 8
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.59494 38.2 10