Development Level

Tdark 22 | 6,588
Tbio 19 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 4 | 298
increased lean body mass 4 | 172
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
abnormal bone structure 2 | 187
decreased circulating serum al... 2 | 82
hyperactivity 2 | 148
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal iris morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
absent spleen 1 | 3
brachydactyly 1 | 19
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged urinary bladder 1 | 8
female infertility 1 | 60
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
male infertility 1 | 123
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
syndactyly 1 | 23

Disease

Carcinoma 22 | 11,493
osteosarcoma 22 | 7,950
ovarian cancer 22 | 8,520
medulloblastoma, large-cell 13 | 6,241
glioblastoma 12 | 5,792
psoriasis 12 | 6,694
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
adult high grade glioma 8 | 3,801
Breast cancer 6 | 3,578
Cancer 6 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
pancreatic cancer 6 | 2,398
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Intellectual disability 3 | 1,016
acute myeloid leukemia 3 | 783
chronic rhinosinusitis 3 | 512
interstitial cystitis 3 | 2,312
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
tuberculosis and treatment for 6 months 3 | 409
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Cognitive delay 2 | 608
Conductive hearing loss 2 | 123
Epilepsy 2 | 792
Global developmental delay 2 | 608
Kidney cancer 2 | 2,613
Leukemia 2 | 104
Mammary Neoplasms 2 | 425
Mental and motor retardation 2 | 608
Myalgia 2 | 54
Myopia 2 | 176
Parkinson's disease 2 | 392
Rheumatoid arthritis 2 | 1,191
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
gastric cancer 2 | 459
hereditary spastic paraplegia 2 | 318
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
posterior fossa group A ependymoma 2 | 468
ulcerative colitis 2 | 1,819
Abnormal vision 1 | 52
Abnormality of the pharynx 1 | 19
Acne 1 | 52
Benign epilepsy with centrotemporal spikes 1 | 13
Calculus in biliary tract 1 | 2
Carcinoma, squamous cell of head and neck 1 | 31
Cocaine Dependence 1 | 51
Conduct disorder 1 | 33
Congenital hypoplasia of kidney 1 | 32
Convex nasal bridge 1 | 57
Eating disorder 1 | 26
Gaucher disease type 3 1 | 67
Hypocalcemia 1 | 32
Hypoparathyroidism 1 | 41
Kleefstra syndrome 1 | 12
Leiomyoma 1 | 32
Marijuana Abuse 1 | 31
Musculoskeletal Pain 1 | 3
Nicotine dependence 1 | 54
Overfolded helix 1 | 24
Pain 1 | 103
Pheochromocytoma 1 | 24
Precancerous Conditions 1 | 80
Prominent nasal bridge 1 | 57
Rotting teeth 1 | 73
Soft skin 1 | 17
Squamous cell carcinoma of the head and neck 1 | 29
Testicular Germ Cell Tumor 1 | 14
Uterine fibroid 1 | 28
Velvety skin 1 | 17
obsessive-compulsive disorder 1 | 61

Tissue

Endocrine System 46 | 18,159
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Blood and immune system 45 | 16,909
Digestive Tract 45 | 17,369
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Respiratory system 45 | 16,393
Skin and soft tissues 45 | 17,230
Urinary Tract 45 | 16,678
Cardiovascular System 44 | 15,192

Target Family

Enzyme 30 | 4,145
TF/Epigenetic 8 | 38
Epigenetic 7 | 242
Non-IDG 3 | 12,091

GO Function

methyltransferase activity 48 | 48
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative methyltransferase-like protein 21E pseudogene METTL21EP Tdark Enzyme 0.00000 0
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221
Methyltransferase-like protein 23 METTL23 Tdark Enzyme -0.17609 1.92 6
Putative protein FAM86C2P FAM86C2P Tdark Enzyme 0.00000 0
Methylated-DNA--protein-cysteine methyltransferase MGMT Tchem Enzyme -3.13356 1426.9 560
Methyltransferase-like protein 12, mitochondrial CSKMT Tdark Enzyme 0.00000 1.08 6
SET and MYND domain-containing protein 4 SMYD4 Tdark Epigenetic 0.08 1.23 128
PR domain zinc finger protein 15 PRDM15 Tdark TF/Epigenetic -0.38844 2.87 83
PR domain zinc finger protein 12 PRDM12 Tbio TF/Epigenetic -0.96029 10.5 105
Zinc finger CCHC domain-containing protein 4 ZCCHC4 Tdark Non-IDG 0.78 0.22 43