Development Level

Tbio 38 | 11,445
Tchem 10 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
vertebral transformation 3 | 12
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
fusion of vertebral arches 1 | 7
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 33 | 11,493
osteosarcoma 30 | 7,950
ovarian cancer 27 | 8,520
glioblastoma 22 | 5,792
medulloblastoma, large-cell 22 | 6,241
psoriasis 22 | 6,694
group 3 medulloblastoma 19 | 4,104
atypical teratoid / rhabdoid tumor 17 | 5,112
ependymoma 16 | 4,679
lung cancer 16 | 4,740
primitive neuroectodermal tumor 14 | 3,035
Breast cancer 13 | 3,578
Cancer 13 | 2,499
malignant mesothelioma 13 | 3,232
Kidney cancer 12 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
oligodendroglioma 10 | 2,850
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
Pick disease 8 | 1,894
astrocytic glioma 8 | 2,597
non-small cell lung cancer 8 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pediatric high grade glioma 7 | 1,064
ulcerative colitis 7 | 1,819
Intellectual disability 6 | 1,016
subependymal giant cell astrocytoma 6 | 2,287
Autistic Disorder 5 | 364
Rheumatoid arthritis 5 | 1,191
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
pancreatic cancer 5 | 2,398
Amyotrophic lateral sclerosis 4 | 451
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
medulloblastoma 4 | 720
progressive supranuclear palsy 4 | 676
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Cognitive delay 3 | 608
Cryptorchidism 3 | 296
Down syndrome 3 | 499
Dull intelligence 3 | 645
Endometrial stromal sarcoma 3 | 15
Epilepsy 3 | 792
Global developmental delay 3 | 608
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Mild Mental Retardation 3 | 70
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Poor school performance 3 | 645
Seizures 3 | 596
Sertoli cell-only syndrome 3 | 37
Small testicle 3 | 75
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,696
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
sonic hedgehog group medulloblastoma 3 | 467
Adenoid Cystic Carcinoma 2 | 99
Adenoma 2 | 167
Attention deficit hyperactivity disorder 2 | 278
Carcinoma, Adenoid Cystic 2 | 99
Cerebral atrophy 2 | 178
Chronic obstructive pulmonary disease 2 | 184
Delayed bone age 2 | 136
Dementia 2 | 175
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Failure to gain weight 2 | 365
Gastroesophageal reflux disease 2 | 110
Heartburn 2 | 78
Infertility 2 | 188
Leukemia 2 | 104
Liver cancer 2 | 604
Melanoma 2 | 711
Neuroblastoma 2 | 80
Pediatric failure to thrive 2 | 365
Schizophrenia 2 | 1,160
Stomach Neoplasms 2 | 300
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
nasopharyngeal carcinoma 2 | 1,058
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409

Tissue

Endocrine System 50 | 18,159
Blood and immune system 49 | 16,909
Digestive Tract 48 | 17,369
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Respiratory system 48 | 16,393
Urinary Tract 48 | 16,678
Cardiovascular System 47 | 15,192
Female tissues 47 | 17,400
Nervous System 47 | 16,725
Skin and soft tissues 47 | 17,230

Target Family

Epigenetic 37 | 242
Non-IDG 10 | 12,091
TF/Epigenetic 2 | 38
Enzyme 1 | 4,145

GO Function

methylated histone binding 50 | 50
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inhibitor of growth protein 3 ING3 Tbio Epigenetic -2.33680 199.4 175
Condensin-2 complex subunit G2 NCAPG2 Tbio Non-IDG -0.75957 5.48 110
Inhibitor of growth protein 1 ING1 Tbio Epigenetic -2.05417 130.8 341
Testis-specific chromodomain protein Y 1 CDY1 Tbio Epigenetic -1.26646 18.6 30
PHD finger protein 1 PHF1 Tbio Epigenetic -2.14039 127.5 199
MBT domain-containing protein 1 MBTD1 Tdark Epigenetic -0.59314 4.06 83
Chromobox protein homolog 8 CBX8 Tchem Epigenetic -2.27537 183.4 505
Chromodomain Y-like protein 2 CDYL2 Tbio Epigenetic -1.13271 10.6 61
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Chromobox protein homolog 2 CBX2 Tchem Epigenetic -1.37369 24.3 223