Development Level

Tbio 14 | 11,445
Tchem 9 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased grip strength 2 | 116
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
aorta stenosis 1 | 2
cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
decreased neutrophil cell numb... 1 | 42
enlarged heart 1 | 210
enlarged liver 1 | 2
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased anxiety-related resp... 1 | 2
increased effector memory CD4-... 1 | 1
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 22 | 11,493
psoriasis 12 | 6,694
ovarian cancer 11 | 8,520
glioblastoma 9 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
medulloblastoma, large-cell 8 | 6,241
diabetes mellitus 7 | 1,728
ependymoma 7 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung cancer 7 | 4,740
lung carcinoma 7 | 2,843
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Kidney cancer 5 | 2,613
cystic fibrosis 5 | 1,696
invasive ductal carcinoma 5 | 2,951
osteosarcoma 5 | 7,950
Asthma 4 | 385
active Crohn's disease 4 | 922
interstitial cystitis 4 | 2,312
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
group 4 medulloblastoma 3 | 1,855
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of metabolism/homeostasis 2 | 134
Atherosclerosis 2 | 291
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Liver Cirrhosis 2 | 181
Mental Depression 2 | 333
Obesity 2 | 678
Pancreatitis 2 | 123
Pick disease 2 | 1,894
Prostate cancer 2 | 175
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Silver-Russell syndrome 2 | 39
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Alcohol dependence 1 | 107
Amebiasis 1 | 21
Arachnodactyly 1 | 49
Cataract 8 multiple types 1 | 33
Decreased platelet count 1 | 111
Dental caries 1 | 164
Dermatologic disorders 1 | 93
Diabetic Nephropathies 1 | 37
Dry skin 1 | 75
Factor XI Deficiency 1 | 12
Gaucher disease type 1 1 | 180
Generalized hirsutism 1 | 36
Infectious disease of lung 1 | 29
Insulin Resistance 1 | 72
Isolated cleft palate 1 | 4
Knee joint valgus deformity 1 | 56
Low posterior hairline 1 | 52
Lupus Erythematosus, Systemic 1 | 67
Multiple pulmonary infections 1 | 29
Nerve Degeneration 1 | 121
Palmoplantar keratosis 1 | 74
Pruritus 1 | 58
Pulmonary hypertension 1 | 85
Recurrent pneumonia 1 | 29
Recurrent pulmonary infections 1 | 29
Retinitis pigmentosa 3 1 | 16
Seborrheic dermatitis 1 | 31
Severe acute respiratory syndrome 1 | 27
Thrombocytopenia 1 | 197
Tracheomalacia 1 | 22
Xerosis 1 | 75
Yaws 1 | 7
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
interstitial lung disease 1 | 298
non-small cell lung cancer and chronic obstructive pulmonary disease 1 | 8
non-small cell lung carcinoma 1 | 317

Tissue

Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Male tissues 24 | 17,142
Urinary Tract 24 | 16,678
Blood and immune system 23 | 16,909
Liver and Pancreas 23 | 16,750
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Cardiovascular System 19 | 15,192

Target Family

Enzyme 25 | 4,145
Non-IDG 1 | 12,091

GO Function

metallocarboxypeptidase activi... 26 | 26
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Angiotensin-converting enzyme 2 ACE2 Tchem Enzyme -3.00188 1129.3 720
Putative N-acetylated-alpha-linked acidic dipeptidase FOLH1B Tbio Enzyme -3.08831 2219.0 0
Carboxypeptidase A4 CPA4 Tbio Enzyme -1.69484 48.3 61
Carboxypeptidase B CPB1 Tchem Enzyme -2.97696 883.0 228
Mast cell carboxypeptidase A CPA3 Tchem Enzyme -1.72972 50.2 151
Carboxypeptidase A1 CPA1 Tchem Enzyme -1.95541 84.1 265
Carboxypeptidase E CPE Tbio Enzyme -3.01460 1019.8 229
Cytosolic carboxypeptidase-like protein 5 AGBL5 Tbio Enzyme -0.97543 10.5 132
Carboxypeptidase B2 CPB2 Tchem Enzyme -2.74770 659.0 375
Adipocyte enhancer-binding protein 1 AEBP1 Tbio Non-IDG -1.54371 39.5 142