Development Level

Tchem 15 | 1,598
Tbio 4 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal behavior 2 | 298
abnormal cranium morphology 1 | 36
abnormal esophagus morphology 1 | 5
abnormal eye morphology 1 | 68
abnormal pancreas morphology 1 | 13
abnormal skin coloration 1 | 25
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
anophthalmia 1 | 33
athymia 1 | 2
decreased circulating chloride... 1 | 30
decreased circulating phosphat... 1 | 27
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating creatini... 1 | 38
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 9 | 8,520
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 7 | 5,792
malignant mesothelioma 7 | 3,232
adult high grade glioma 6 | 3,801
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
psoriasis 5 | 6,694
Cancer 4 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
Breast cancer 3 | 3,578
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
esophageal adenocarcinoma 3 | 737
lung adenocarcinoma 3 | 2,716
nephrosclerosis 3 | 333
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Ankylosing spondylitis 2 | 140
Arthritis 2 | 290
Asthma 2 | 385
Asymptomatic dengue 2 | 5
Behcet's disease 2 | 89
Bipolar Disorder 2 | 666
Common variable immunodeficiency 2 | 101
Crohn's disease 2 | 321
Hypertension 2 | 396
Major Depressive Disorder 2 | 301
Mammary Neoplasms, Experimental 2 | 154
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Unipolar Depression 2 | 250
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
group 4 medulloblastoma 2 | 1,855
inflammatory breast cancer 2 | 286
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
Abdominal Pain 1 | 98
Abnormal blistering of the skin 1 | 54
Acquired immunodeficiency syndrome 1 | 197
Acquired metabolic disease 1 | 336
Adenocarcinoma 1 | 122
Antiphospholipid syndrome 1 | 19
Arthralgia 1 | 90
Barrett's esophagus 1 | 182
Blister of skin 1 | 54
Breast Neoplasms 1 | 445
Chronic heart failure 1 | 46
Crohn Disease 1 | 45
Dental caries 1 | 164
Esophageal Neoplasms 1 | 69
Fatigue 1 | 182
Fever 1 | 138
Heart conduction disease 1 | 83
Intermittent migraine headaches 1 | 68
Mammary Neoplasms 1 | 425
Meningitis 1 | 67
Migraine Disorders 1 | 76
Nausea and vomiting 1 | 97
Photodysphoria 1 | 121
Photophobia 1 | 121
Placental insufficiency 1 | 18
Pre-Eclampsia 1 | 68
Skin bulla 1 | 54
Thickened facial skin with coarse facial features 1 | 108
Thrombocytopenia 1 | 197
Vaccinia 1 | 36
Venous Thrombosis 1 | 47
facioscapulohumeral dystrophy 1 | 288
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
interstitial lung disease 1 | 298
permanent atrial fibrillation 1 | 45

Tissue

Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Nervous System 18 | 16,725
Respiratory system 18 | 16,393

Target Family

Enzyme 20 | 4,145

GO Function

metalloaminopeptidase activity 20 | 20
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Aminopeptidase Q LVRN Tbio Enzyme -1.93108 81.3 15
Endoplasmic reticulum aminopeptidase 2 ERAP2 Tchem Enzyme -1.73764 53.1 76
Matrix metalloproteinase-17 MMP17 Tchem Enzyme -1.40823 27.2 217
Puromycin-sensitive aminopeptidase-like protein NPEPPSL1 Tdark Enzyme 0.00000 0
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.69065 43.4 351
Xaa-Pro aminopeptidase 2 XPNPEP2 Tchem Enzyme -1.61390 35.9 110
Matrix metalloproteinase-16 MMP16 Tchem Enzyme -1.80934 59.5 301
Aminopeptidase B RNPEP Tchem Enzyme -2.88402 763.4 140
Leukotriene A-4 hydrolase LTA4H Tchem Enzyme -2.11151 125.3 291