Development Level

Tdark 8 | 6,588
Tbio 7 | 11,445

IMPC Phenotype

decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
decreased circulating free fat... 1 | 31
decreased erythrocyte cell num... 1 | 62
enlarged heart 1 | 210
increased monocyte cell number 1 | 63
long tibia 1 | 25
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Congenital disorder of glycosylation 3 | 54
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
medulloblastoma, large-cell 3 | 6,241
mucosa-associated lymphoid tissue lymphoma 3 | 484
subependymal giant cell astrocytoma 3 | 2,287
Absent speech 2 | 43
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Globe of eye large 2 | 20
Infertility 2 | 188
Intellectual disability 2 | 1,016
Klinefelter's syndrome 2 | 56
Male infertility 2 | 206
Primary ciliary dyskinesia 2 | 76
Severe mental retardation (I.Q. 20-34) 2 | 99
Varicocele 2 | 26
Walker-Warburg syndrome 2 | 20
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
nonverbal 2 | 43
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Absent auditory canals 1 | 23
Absent external auditory canals 1 | 23
Alpha 1-antitrypsin deficiency 1 | 11
Atresia of the external auditory canal 1 | 23
Atretic auditory canal 1 | 23
Atrophic retina 1 | 7
Cerebellar dysplasia 1 | 8
Chromosome 17q12 deletion syndrome 1 | 16
Class III malocclusion 1 | 78
Clouding of corneal stroma 1 | 50
Congenital disorder of glycosylation type 1G 1 | 1
Congenital muscular dystrophy (disorder) 1 | 14
Corneal diameter increased 1 | 13
Easy fatigability 1 | 18
Electromyogram abnormal 1 | 49
Enlarged cisterna magna 1 | 2
Excessive daytime somnolence 1 | 14
Facial muscle weakness of muscles innervated by CN VII 1 | 58
Flexion contractures of joints 1 | 93
Highly variable severity 1 | 157
Hirschsprung's disease 1 | 46
Hypertrophy of lower jaw 1 | 78
Hypoplasia of the brainstem 1 | 22
Hypoplastic male genitalia 1 | 7
Hypotonia, severe 1 | 33
Hypotrophic malar bone 1 | 129
Imperforate anus 1 | 25
Increased size of mandible 1 | 78
Intracranial aneurysm 1 | 24
Inverted V-shaped upper lip 1 | 19
Limb-girdle muscle weakness 1 | 12
Limb-girdle muscular dystrophy-dystroglycanopathy, type C1 1 | 1
Lumbar lordosis 1 | 35
MUSCULAR DYSTROPHY, CONGENITAL, 1C 1 | 9
MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K 1 | 1
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 1 1 | 7
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 14 1 | 7
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 2 1 | 7
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (LIMB-GIRDLE), TYPE C, 1 1 | 1
Malar flattening 1 | 129
Mandibular hyperplasia 1 | 78
Mental impairment 1 | 95
Midface retrusion 1 | 105
Motor delay 1 | 147
Muscle biopsy shows dystrophic changes 1 | 39
Muscle-eye-brain disease 1 | 8
Muscular Dystrophy, Congenital, Type 1D 1 | 5
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain and Eye Anomalies), Type A, 1 1 | 6
No development of motor milestones 1 | 147
Posterior fossa cyst 1 | 8
Profound intellectual disabilities 1 | 31
RENAL ADYSPLASIA 1 | 25
Renal dysplasia 1 | 28
Short philtrum 1 | 53
Slow progression 1 | 89
Small midface 1 | 105
Spinal rigidity 1 | 13
Tapering fingers (finding) 1 | 25
Tented mouth 1 | 19
Tented upper lip 1 | 19
Thick cerebral cortex 1 | 5
Thin upper lip vermilion 1 | 67
Variable expressivity 1 | 157
Visual Impairment 1 | 174
Williams-Beuren syndrome 1 | 50
cystic fibrosis and chronic rhinosinusitis 1 | 214
mandibular excess (physical finding) 1 | 78

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Skin and soft tissues 13 | 17,230
Cardiovascular System 12 | 15,192
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Urinary Tract 12 | 16,678

Target Family

Enzyme 15 | 4,145

GO Function

mannosyltransferase activity 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein O-mannosyl-transferase 1 POMT1 Tbio Enzyme -1.57372 38.3 123
GPI mannosyltransferase 4 PIGZ Tdark Enzyme -1.18571 13.8 39
GPI mannosyltransferase 2 PIGV Tbio Enzyme -1.07565 13.4 71
Probable C-mannosyltransferase DPY19L3 DPY19L3 Tdark Enzyme -0.34406 1.15 63
Putative glycosyltransferase ALG1L2 ALG1L2 Tdark Enzyme 0.00000 3
Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1 Tbio Enzyme -1.73564 56.8 97
Putative C-mannosyltransferase DPY19L2P2 DPY19L2P2 Tdark Enzyme -1.83182 120.9 0
GPI mannosyltransferase 3 PIGB Tbio Enzyme -1.30392 19.1 79
Probable C-mannosyltransferase DPY19L4 DPY19L4 Tdark Enzyme 0.60 0.14 84
Putative C-mannosyltransferase DPY19L2P1 DPY19L2P1 Tdark Enzyme 0.00000 0