Development Level

Tbio 2 | 11,445

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 2 | 11,493
Epilepsy 2 | 792
Intellectual disability 2 | 1,016
Iridogoniodysgenesis syndrome 2 | 9
ependymoma 2 | 4,679
osteosarcoma 2 | 7,950
Adenocarcinoma of lung 1 | 142
Agenesis of corpus callosum 1 | 83
Amblyopia 1 | 38
Anteverted nostril 1 | 191
Atrial Septal Defects 1 | 85
Autosomal recessive predisposition 1 | 1,442
Big calvaria 1 | 147
Bilateral fifth finger clinodactyly 1 | 110
Broad flat nasal bridge 1 | 236
Broad forehead 1 | 59
Byzanthine arch palate 1 | 194
Cerebral atrophy 1 | 178
Choreoathetoid movements 1 | 32
Choreoathetosis 1 | 32
Clouding of corneal stroma 1 | 50
Coarse facial features 1 | 108
Cognitive delay 1 | 608
Concave bridge of nose 1 | 195
Congenital Epicanthus 1 | 177
Congenital diaphragmatic hernia 1 | 67
Congenital hypoplasia of lung 1 | 48
Corneal Opacity 1 | 53
Curvature of little finger 1 | 110
Decreased tendon reflex 1 | 122
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Disease Models, Animal 1 | 155
Dull intelligence 1 | 645
Excess nuchal skin 1 | 30
Gastroesophageal reflux disease 1 | 110
Global developmental delay 1 | 608
Global developmental delay, severe 1 | 47
Glomerulonephritis 1 | 46
Heart Septal Defects 1 | 24
Heartburn 1 | 78
Hydronephrosis 1 | 89
Hyperphosphatasia with Mental Retardation 1 | 5
Hyperreflexia 1 | 209
Hypoplastic fingernails 1 | 11
Hypoplastic mandible condyle 1 | 275
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Inverted V-shaped upper lip 1 | 19
Large fleshy ears 1 | 2
Long philtrum 1 | 137
Low intelligence 1 | 645
Low-set, posteriorly rotated ears 1 | 110
Macrostomia 1 | 72
Mandibular hypoplasia 1 | 275
Median cleft lip 1 | 7
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Micrognathism 1 | 275
Multicystic Dysplastic Kidney 1 | 52
Multiple congenital anomalies-hypotonia-seizures syndrome 1 1 | 2
Muscle hypotonia 1 | 571
Narrow forehead 1 | 34
Nasal bridge wide 1 | 236
Nipples absent or rudimentary 1 | 3
Non-midline cleft lip 1 | 6
Nystagmus 1 | 317
Open mouth 1 | 45
Orbital separation excessive 1 | 244
Overfolded helix 1 | 24
Paget's disease of bone 1 | 36
Patent ductus arteriosus 1 | 90
Pick disease 1 | 1,894
Polyhydramnios 1 | 108
Poor school performance 1 | 645
Prenatal onset 1 | 139
Proteinuria 1 | 144
Seizures 1 | 596
Severe psychomotor retardation 1 | 47
Short distal phalanges 1 | 50
Short neck 1 | 140
Short nose 1 | 132
Small nose 1 | 132
Stricture of anus 1 | 13
Tented mouth 1 | 19
Tented upper lip 1 | 19
Testicular Hydrocele 1 | 8
Tetralogy of Fallot 1 | 63
Thickened facial skin with coarse facial features 1 | 108
Thin lips 1 | 49
Tremor 1 | 113
Uranostaphyloschisis 1 | 167
Wide spaced nipples 1 | 46
glioblastoma 1 | 5,792
lung cancer 1 | 4,740
ovarian cancer 1 | 8,520
psoriasis 1 | 6,694
tuberculosis 1 | 2,010

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

GO Function

mannose-ethanolamine phosphotr... 2 | 2
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GPI ethanolamine phosphate transferase 1 PIGN Tbio Enzyme -1.94396 89.9 52
GPI ethanolamine phosphate transferase 3 PIGO Tbio Enzyme -0.99466 10.6 107