Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 1 | 499

Disease

glioblastoma 4 | 5,792
psoriasis 4 | 6,694
Carcinoma 3 | 11,493
Parkinson's disease 3 | 392
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
ulcerative colitis 3 | 1,819
Autosomal recessive predisposition 2 | 1,442
Dystonia 2 | 164
Hemochromatosis 2 | 54
Neurodegenerative disease 2 | 414
atypical teratoid / rhabdoid tumor 2 | 5,112
colon cancer 2 | 1,478
ependymoma 2 | 4,679
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
tuberculosis 2 | 2,010
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of the liver 1 | 21
Acquired metabolic disease 1 | 336
Acute kidney injury 1 | 70
Anemia 1 | 365
Arthritis, Juvenile 1 | 126
Barrett's esophagus 1 | 182
Bradykinesia 1 | 34
Brucellosis 1 | 24
Cholestasis 1 | 155
Colitis, Ulcerative 1 | 59
Coughing 1 | 25
Crohn Disease 1 | 45
Decreased liver function 1 | 24
Dermatitis, Atopic 1 | 37
Dysarthria 1 | 192
Dystonic disease 1 | 106
Elevated hepatic transaminases 1 | 81
Endometriosis 1 | 540
Enterobiasis 1 | 5
Erythrocytosis 1 | 8
Fatigue 1 | 182
Fever 1 | 138
Food allergy 1 | 8
HIV Infections 1 | 102
Hemoglobin low 1 | 124
Hepatic enzyme increased 1 | 81
Hepatomegaly 1 | 285
Highly variable severity 1 | 157
Human immunodeficiency virus infectious disease 1 | 138
Inflammatory Bowel Diseases 1 | 35
Insulinoma 1 | 24
Juvenile arthritis 1 | 126
Juvenile rheumatoid arthritis 1 | 111
Large intestine cancer 1 | 126
Leishmaniasis 1 | 47
Leishmaniasis, Visceral 1 | 13
Leprosy 1 | 73
Liver Cirrhosis 1 | 181
Liver Dysfunction 1 | 99
Liver diseases 1 | 87
Liver dysfunction, mild 1 | 24
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Liver neoplasms 1 | 130
Lung diseases 1 | 50
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO 1 | 11
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 1 | 11
Multiple Sclerosis 1 | 540
Muscle Rigidity 1 | 49
Mycobacterium avium complex disease 1 | 11
Osteoarthritis 1 | 184
Parkinson Disease 1 | 64
Parkinsonian Disorders 1 | 56
Polycythemia 1 | 25
Postural instability 1 | 19
Respiratory Hypersensitivity 1 | 19
Salmonellosis 1 | 42
Subclinical abnormal liver function tests 1 | 81
Toxic encephalopathy 1 | 141
Transaminases increased 1 | 81
Tremor 1 | 113
Typhoid fever 1 | 22
Variable expressivity 1 | 157
Visceral leishmaniasis 1 | 14
Weight decreased 1 | 103
active Crohn's disease 1 | 922
adrenocortical carcinoma 1 | 1,428
cystic fibrosis 1 | 1,696
esophageal adenocarcinoma 1 | 737
head and neck cancer 1 | 271
lung adenocarcinoma 1 | 2,716
mucosa-associated lymphoid tissue lymphoma 1 | 484
nasopharyngeal carcinoma 1 | 1,058
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
sarcoidosis 1 | 370

Tissue

Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Liver and Pancreas 4 | 16,750
Nervous System 4 | 16,725
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Female tissues 3 | 17,400
Male tissues 3 | 17,142
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Transporter 4 | 473

GO Function

manganese ion transmembrane tr... 4 | 4
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc transporter 10 SLC30A10 Tbio Transporter -2.10372 124.4 81
Natural resistance-associated macrophage protein 1 SLC11A1 Tbio Transporter -2.77524 629.3 129
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.53965 373.5 250
Zinc transporter ZIP14 SLC39A14 Tbio Transporter -1.68719 48.5 117