Development Level

Tbio 12 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased circulating HDL chol... 1 | 68
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased bone mineral content 1 | 108
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 12 | 8,520
Carcinoma 10 | 11,493
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
glioblastoma 8 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
astrocytic glioma 7 | 2,597
atypical teratoid / rhabdoid tumor 7 | 5,112
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
oligodendroglioma 6 | 2,850
psoriasis 6 | 6,694
Autosomal recessive predisposition 4 | 1,442
interstitial cystitis 4 | 2,312
lung cancer 4 | 4,740
subependymal giant cell astrocytoma 4 | 2,287
Angelman syndrome 3 | 34
Breast cancer 3 | 3,578
Epilepsy 3 | 792
Liver Cirrhosis, Experimental 3 | 769
Pick disease 3 | 1,894
Prader-Willi syndrome 3 | 48
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
medulloblastoma 3 | 720
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Dull intelligence 2 | 645
Huntington's disease 2 | 76
Hypomagnesemia 2 | 12
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Nephronophthisis 2 | 80
Nystagmus 2 | 317
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Seizures 2 | 596
Tetany 2 | 18
Urofacial syndrome 2 | 7
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
Abdominal Pain 1 | 98
Abnormality of retinal pigmentation 1 | 111
Alopecia 1 | 115
Astigmatism 1 | 54
Autism spectrum disorder 1 | 101
Autosomal recessive congenital ichthyosis 1 | 11
Azoospermia 1 | 110
Botulism 1 | 24
Cardiac Arrhythmia 1 | 103
Cone dystrophy 1 | 71
Dental caries 1 | 164
Difficulties with night vision 1 | 87
Dizziness 1 | 26
Fundus dystrophy 1 | 83
Gout 1 | 106
Headache 1 | 37
Hyperopia 1 | 70
Hyperuricemia 1 | 49
Ichthyosis 1 | 56
Intracranial aneurysm 1 | 24
Kidney Diseases 1 | 114
Low Vision 1 | 174
Lymphopenia 1 | 67
Muscle Weakness 1 | 170
Myopia 1 | 176
Nephrocalcinosis 1 | 35
Nephrolithiasis 1 | 56
Neurodegenerative disease 1 | 414
Night Blindness 1 | 101
Osteoporosis 1 | 363
Pallor of optic disc 1 | 39
Paraplegia 1 | 74
Parkinson's disease 1 | 392
Photodysphoria 1 | 121
Photophobia 1 | 121
Recurrent urinary tract infection 1 | 24
Relapsing fever 1 | 14
Renal tubular acidosis 1 | 24
Retinal pigment epithelial abnormality 1 | 111
Rickets 1 | 49
Rotting teeth 1 | 73
Vertigo 1 | 29
Visual Impairment 1 | 174
hereditary spastic paraplegia 1 | 318
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 2 | 4,145
Transporter 2 | 473

GO Function

magnesium ion transmembrane tr... 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
Magnesium transporter MRS2 homolog, mitochondrial MRS2 Tbio Non-IDG -2.52322 327.4 39
Solute carrier family 41 member 1 SLC41A1 Tbio Transporter -1.94210 82.1 23
Metal transporter CNNM4 CNNM4 Tbio Non-IDG -1.18531 16.5 123
Palmitoyltransferase ZDHHC13 ZDHHC13 Tbio Enzyme -0.87916 8.35 133
Magnesium transporter NIPA1 NIPA1 Tbio Non-IDG -1.41490 24.2 20
Magnesium transporter protein 1 MAGT1 Tbio Non-IDG -1.60224 37.5 86
Magnesium transporter NIPA4 NIPAL4 Tbio Non-IDG -1.20246 15.0 58
Palmitoyltransferase ZDHHC17 ZDHHC17 Tbio Enzyme -1.42901 31.1 142
Magnesium transporter NIPA3 NIPAL1 Tdark Non-IDG -0.17609 0.67 57