Development Level

Tbio 10 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

fusion of vertebral arches 1 | 7
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

osteosarcoma 7 | 7,950
Carcinoma 6 | 11,493
Cancer 5 | 2,499
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
Systemic lupus erythematosus 3 | 194
Waldenstrons macroglobulinemia 3 | 765
atypical teratoid / rhabdoid tumor 3 | 5,112
cystic fibrosis 3 | 1,696
lung cancer 3 | 4,740
primitive neuroectodermal tumor 3 | 3,035
Adenocarcinoma of lung 2 | 142
Disease Models, Animal 2 | 155
Dyskeratosis congenita 2 | 24
Multiple myeloma 2 | 1,332
Rheumatoid arthritis 2 | 1,191
Severe combined immunodeficiency 2 | 51
Werner syndrome 2 | 29
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Adult T-Cell Lymphoma/Leukemia 1 | 30
Alcoholic Intoxication, Chronic 1 | 289
Allergic hypersensitivity disease 1 | 126
Alzheimer's disease 1 | 658
Arthritis 1 | 290
Ataxia telangiectasia 1 | 34
Autoimmune Diseases 1 | 67
Blastic phase chronic myeloid leukemia 1 | 58
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic phase chronic myeloid leukemia 1 | 45
Colorectal Neoplasms 1 | 243
Crohn's disease 1 | 321
DNA ligase IV deficiency 1 | 7
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 54 1 | 1
Epidermolysis bullosa acquisita 1 | 10
Epilepsy 1 | 792
Fanconi anemia 1 | 56
Glomerulonephritis 1 | 46
HOYERAAL-HREIDARSSON SYNDROME 1 | 6
Hereditary Melanoma 1 | 12
Hydronephrosis 1 | 89
Leukemia-Lymphoma, Adult T-Cell 1 | 30
Lupus Erythematosus, Systemic 1 | 67
MELANOMA, CUTANEOUS MALIGNANT, 1 1 | 13
Malaria 1 | 160
Malignant neoplasm of prostate 1 | 11
Melanoma 1 | 711
Metal allergy 1 | 5
Microcephaly 1 | 166
Neutropenia 1 | 72
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pick disease 1 | 1,894
Prostate cancer 1 | 175
Prostate cancer, familial 1 | 13
Skin cancer 1 | 469
Thrombocytopenia 1 | 197
Xeroderma pigmentosum 1 | 43
Xeroderma pigmentosum group F 1 | 22
active Crohn's disease 1 | 922
acute myeloid leukemia 1 | 783
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
atypical teratoid/rhabdoid tumor 1 | 357
breast carcinoma 1 | 1,638
cutaneous lupus erythematosus 1 | 1,057
familial melanoma 1 | 10
gastric cancer 1 | 459
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
periodontitis 1 | 293
permanent atrial fibrillation 1 | 45
primary Sjogren syndrome 1 | 735
sarcoidosis 1 | 370
second-degree atrioventricular block 1 | 4
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

GO Function

macromolecular complex binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Telomeric repeat-binding factor 2 TERF2 Tbio Transcription Factor -2.23836 174.6 367
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B Tbio Non-IDG -2.61667 619.4 476
X-ray repair cross-complementing protein 6 XRCC6 Tbio Non-IDG -2.86424 688.3 865
Adrenocortical dysplasia protein homolog ACD Tbio Non-IDG -2.42999 246.5 205
182 kDa tankyrase-1-binding protein TNKS1BP1 Tbio Enzyme -0.22432 2.13 144
5' exonuclease Apollo DCLRE1B Tbio Enzyme -1.15231 16.0 78
PIN2/TERF1-interacting telomerase inhibitor 1 PINX1 Tbio Transcription Factor -1.96356 100.2 168