Development Level

Tbio 106 | 11,445
Tdark 7 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 5 | 499
abnormal embryo size 2 | 220
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal skin coloration 1 | 25
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
aorta dilation 1 | 3
cataract 1 | 92
decreased IgE level 1 | 6
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased grip strength 1 | 41
increased hematocrit 1 | 46
male infertility 1 | 123
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
small testis 1 | 58
thin ventricular wall 1 | 24
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 73 | 8,520
Carcinoma 72 | 11,493
osteosarcoma 59 | 7,950
medulloblastoma, large-cell 50 | 6,241
lung cancer 47 | 4,740
psoriasis 42 | 6,694
group 3 medulloblastoma 41 | 4,104
atypical teratoid / rhabdoid tumor 40 | 5,112
glioblastoma 40 | 5,792
ependymoma 31 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
primitive neuroectodermal tumor 27 | 3,035
acute quadriplegic myopathy 26 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
Breast cancer 25 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
oligodendroglioma 24 | 2,850
Kidney cancer 23 | 2,613
Multiple myeloma 23 | 1,332
Waldenstrons macroglobulinemia 23 | 765
Cancer 22 | 2,499
lung adenocarcinoma 22 | 2,716
adult high grade glioma 21 | 3,801
Pick disease 20 | 1,894
astrocytic glioma 20 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
malignant mesothelioma 19 | 3,232
dermatomyositis 17 | 966
non-small cell lung cancer 16 | 2,890
subependymal giant cell astrocytoma 16 | 2,287
astrocytoma 15 | 1,146
juvenile dermatomyositis 15 | 1,187
invasive ductal carcinoma 14 | 2,951
pancreatic cancer 14 | 2,398
Astrocytoma, Pilocytic 13 | 3,081
Schizophrenia 11 | 1,160
breast carcinoma 11 | 1,638
lung carcinoma 11 | 2,843
spina bifida 11 | 1,074
diabetes mellitus 10 | 1,728
progressive supranuclear palsy 10 | 676
tuberculosis 10 | 2,010
Intellectual disability 9 | 1,016
colon cancer 9 | 1,478
group 4 medulloblastoma 9 | 1,855
pituitary cancer 9 | 1,972
Amyotrophic lateral sclerosis 8 | 451
ductal carcinoma in situ 8 | 1,745
Alzheimer's disease 7 | 658
Epilepsy 7 | 792
Infertility 7 | 188
Male infertility 7 | 206
acute myeloid leukemia 7 | 783
aldosterone-producing adenoma 7 | 665
cystic fibrosis 7 | 1,696
primary pancreatic ductal adenocarcinoma 7 | 1,109
ulcerative colitis 7 | 1,819
Gaucher disease type 1 6 | 180
Rheumatoid arthritis 6 | 1,191
adrenocortical carcinoma 6 | 1,428
gastric carcinoma 6 | 807
hepatocellular carcinoma 6 | 547
hereditary spastic paraplegia 6 | 318
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
pediatric high grade glioma 6 | 1,064
Atopic dermatitis 5 | 952
Autistic Disorder 5 | 364
Autosomal recessive predisposition 5 | 1,442
Fragile X syndrome 5 | 34
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
interstitial cystitis 5 | 2,312
medulloblastoma 5 | 720
pancreatic carcinoma 5 | 562
tuberculosis and treatment for 3 months 5 | 179
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Cognitive delay 4 | 608
Duchenne muscular dystrophy 4 | 601
Global developmental delay 4 | 608
Lupus erythematosus 4 | 57
Mammary Neoplasms 4 | 425
Mental and motor retardation 4 | 608
Neurodegenerative disease 4 | 414
Seizures 4 | 596
active ulcerative colitis 4 | 764
gastric cancer 4 | 459
primary Sjogren syndrome 4 | 735
relapsing-remitting multiple sclerosis 4 | 18
tuberculosis and treatment for 6 months 4 | 409
Bilateral fifth finger clinodactyly 3 | 110
Curvature of little finger 3 | 110
Down syndrome 3 | 499
Endometriosis 3 | 540
Myocardial Ischemia 3 | 169
Prostatic Neoplasms 3 | 495
Psychotic Disorders 3 | 151
active Crohn's disease 3 | 922
mucosa-associated lymphoid tissue lymphoma 3 | 484
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 115 | 18,159
Digestive Tract 114 | 17,369
Female tissues 114 | 17,400
Urinary Tract 113 | 16,678
Male tissues 112 | 17,142
Blood and immune system 111 | 16,909
Nervous System 111 | 16,725
Respiratory system 111 | 16,393
Skin and soft tissues 111 | 17,230
Cardiovascular System 110 | 15,192
Liver and Pancreas 110 | 16,750

Target Family

Non-IDG 98 | 12,091
Enzyme 14 | 4,145
Epigenetic 3 | 242
Transcription Factor 2 | 1,400
Transporter 1 | 473

GO Function

mRNA binding 118 | 118
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Transcriptional activator protein Pur-beta PURB Tbio Non-IDG -1.49692 30.7 79
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.14189 16.8 116
Polypyrimidine tract-binding protein 2 PTBP2 Tbio Non-IDG -2.05261 113.3 151
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.23341 1462.9 208
Heterogeneous nuclear ribonucleoprotein A/B HNRNPAB Tbio Non-IDG -1.15839 12.5 96
N6-adenosine-methyltransferase catalytic subunit METTL3 Tbio Enzyme -1.76174 60.5 94
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
60S ribosomal protein L35 RPL35 Tbio Non-IDG -1.30696 19.1 124
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161