Development Level

Tchem 10 | 1,885
Tbio 6 | 11,178
Tdark 5 | 6,569

IMPC Phenotype

decreased grip strength 1 | 116
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
vertebral fusion 1 | 23

Disease

Carcinoma 10 | 11,192
medulloblastoma, large-cell 10 | 6,086
osteosarcoma 10 | 7,766
ovarian cancer 7 | 8,297
psoriasis 7 | 6,514
atypical teratoid / rhabdoid tumor 6 | 4,971
ependymoma 6 | 4,559
glioblastoma 6 | 5,635
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,872
invasive ductal carcinoma 6 | 2,867
lung adenocarcinoma 6 | 2,627
Breast cancer 5 | 3,469
Obesity 5 | 655
adult high grade glioma 5 | 3,701
ductal carcinoma in situ 5 | 1,686
group 4 medulloblastoma 5 | 1,806
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,902
subependymal giant cell astrocytoma 5 | 2,230
Kidney cancer 4 | 2,548
breast carcinoma 4 | 1,589
colon cancer 4 | 1,428
interstitial cystitis 4 | 2,237
lung cancer 4 | 4,607
lung carcinoma 4 | 2,755
non-small cell lung cancer 4 | 2,799
pancreatic cancer 4 | 2,322
Autosomal recessive predisposition 3 | 1,407
Ileocolitis 3 | 5
Pick disease 3 | 1,856
Schizophrenia 3 | 1,136
astrocytic glioma 3 | 2,530
diabetes mellitus 3 | 1,683
group 3 medulloblastoma 3 | 4,002
juvenile dermatomyositis 3 | 1,147
primitive neuroectodermal tumor 3 | 2,957
ulcerative colitis 3 | 1,765
Action Tremor 2 | 22
Amyotrophic lateral sclerosis type 1 2 | 23
Astrocytoma, Pilocytic 2 | 3,006
Atrophy of cerebellum 2 | 101
Babinski Reflex 2 | 98
Cerebellar Ataxia 2 | 302
Cerebellar Dysmetria 2 | 55
Cerebellar degeneration 2 | 101
Decreased tendon reflex 2 | 121
Distal amyotrophy 2 | 49
Dysarthria 2 | 190
Highly variable clinical phenotype 2 | 147
Highly variable phenotype and severity 2 | 147
Highly variable phenotype, even within families 2 | 147
Hyperreflexia 2 | 208
Infratentorial atrophy 2 | 101
Liver Cirrhosis, Experimental 2 | 733
Muscle Spasticity 2 | 192
Muscle hypotonia 2 | 562
Neuropathy 2 | 254
Neutral lipid storage disease 2 | 12
Nystagmus 2 | 309
Optic Atrophy 2 | 239
Peripheral Neuropathy 2 | 131
Phenotypic variability 2 | 147
Polyneuropathy 2 | 63
Progressive disorder 2 | 139
Retinitis Pigmentosa 2 | 223
Rheumatoid arthritis 2 | 1,156
Sengers syndrome 2 | 18
Sensorineural Hearing Loss (disorder) 2 | 281
Sjogren-Larsson syndrome 2 | 6
Terminal tremor 2 | 20
acute myeloid leukemia 2 | 760
cystic fibrosis 2 | 1,629
dermatomyositis 2 | 941
hereditary spastic paraplegia 2 | 313
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,204
malignant mesothelioma 2 | 3,135
nasopharyngeal carcinoma 2 | 1,024
pancreatic carcinoma 2 | 555
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,911
pediatric high grade glioma 2 | 1,035
primary pancreatic ductal adenocarcinoma 2 | 1,071
progressive supranuclear palsy 2 | 656
Ataxia, Spinocerebellar 1 | 15
Decreased nerve conduction velocity 1 | 34
Decreased visual acuity, progressive 1 | 35
Fatty liver disease 1 | 102
Hypogonadism, Isolated Hypogonadotropic 1 | 64
Hypogonadotropic hypogonadism 1 | 82
Increased serum pyruvate 1 | 9
Liver disease 1 | 227
Long eyebrows 1 | 2
Nervous System Diseases 1 | 50
Photodysphoria 1 | 117
Photophobia 1 | 117
Pigmentary retinal degeneration 1 | 11
Pre-Eclampsia 1 | 64
Progressive visual loss 1 | 35
Retinal exudates 1 | 11
Spastic Quadriplegia 1 | 41
adrenocortical adenoma 1 | 127
non-small cell lung carcinoma 1 | 302

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Urinary Tract 19 | 16,678
Cardiovascular System 18 | 15,192
Liver and Pancreas 18 | 16,750

Target Family

Enzyme 20 | 4,145
Non-IDG 1 | 12,091

GO Function

lysophospholipase activity 21 | 21
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytosolic phospholipase A2 beta JMJD7-PLA2G4B Tchem Enzyme -0.60640 3.75 104
60 kDa lysophospholipase ASPG Tbio Enzyme -1.29813 17.7 53
Cytosolic phospholipase A2 zeta PLA2G4F Tdark Enzyme 0.59 0.40 38
Calcium-independent phospholipase A2-gamma PNPLA8 Tbio Enzyme -1.96549 89.5 114
Cytosolic phospholipase A2 gamma PLA2G4C Tchem Enzyme -1.27690 20.9 63
Cytosolic phospholipase A2 delta PLA2G4D Tbio Enzyme -0.54284 3.41 45
Phospholipase B-like 1 PLBD1 Tdark Enzyme -0.34063 2.15 52
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 ENPP2 Tchem Enzyme -2.62921 463.2 377
Group XV phospholipase A2 PLA2G15 Tchem Enzyme -1.68759 48.7 88
Patatin-like phospholipase domain-containing protein 7 PNPLA7 Tdark Enzyme -0.71321 5.24 7