Development Level

Tbio 8 | 11,651
Tdark 5 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
increased mean corpuscular hem... 1 | 96

Disease

psoriasis 8 | 6,694
Carcinoma 7 | 11,493
ovarian cancer 6 | 8,519
Breast cancer 4 | 3,577
group 3 medulloblastoma 4 | 4,104
pancreatic cancer 4 | 2,398
Intellectual disability 3 | 1,016
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
pancreatic carcinoma 3 | 562
subependymal giant cell astrocytoma 3 | 2,287
Cancer 2 | 2,499
Deglutition Disorders 2 | 132
Microcephaly 2 | 166
Movement Disorders 2 | 55
Neurodegenerative disease 2 | 414
Pontocerebellar Hypoplasia Type 2 2 | 5
Pontocerebellar hypoplasia 2 | 36
Vision Disorders 2 | 6
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,290
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,108
ADULT syndrome 1 | 9
Adverse reaction to drug 1 | 61
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Alcoholic Intoxication, Chronic 1 | 289
Alzheimer's disease 1 | 658
Anhidrosis 1 | 23
Autosomal recessive congenital ichthyosis 1 | 11
Bladder Neoplasm 1 | 112
Brain disease 1 | 96
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis, Extrahepatic 1 | 25
Colonic Neoplasms 1 | 142
Congenital ichthyosiform erythroderma 1 | 28
Death in early childhood 1 | 82
Death in infancy 1 | 82
Drug-Related Side Effects and Adverse Reactions 1 | 62
Encephalopathies 1 | 43
Epilepsy 1 | 792
Esophageal Squamous Cell Carcinoma 1 | 77
Fever 1 | 138
Gestational diabetes 1 | 26
Glycine encephalopathy 1 | 29
HYPERGLYCINURIA (disorder) 1 | 12
Hyperactive behavior 1 | 91
Hyperalgesia 1 | 83
Hyperreflexia 1 | 209
Hypersensitivity reaction type II disease 1 | 253
Ichthyosis 1 | 56
Inflammation 1 | 120
Irritation - emotion 1 | 68
Lethargy 1 | 77
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Lung disease 1 | 142
Myocardial Infarction 1 | 151
Myocardial Reperfusion Injury 1 | 37
Myoclonus 1 | 74
Necrosis 1 | 53
Neuralgia 1 | 20
Pancreatitis 1 | 123
Peritonitis 1 | 43
Physical aggression 1 | 76
Polycystic ovary syndrome 1 | 360
Polyhydramnios 1 | 108
Pontocerebellar Hypoplasia Type 2C 1 | 1
Pontocerebellar Hypoplasia, Type 2C 1 | 1
Prostate cancer 1 | 175
Pulmonary Fibrosis 1 | 106
Restlessness 1 | 14
Retinitis pigmentosa Y-linked 1 | 9
Seizures 1 | 596
Sepsis 1 | 24
Squamous cell carcinoma of esophagus 1 | 77
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Tinea corporis 1 | 25
Urinary Bladder Neoplasms 1 | 114
Velocardiofacial syndrome 1 | 46
Weight Gain 1 | 100
Werner syndrome 1 | 29
active Crohn's disease 1 | 922
alcohol-related neurodevelopmental disorder 1 | 13
breast carcinoma 1 | 1,637
cystic fibrosis 1 | 1,695
inflammatory breast cancer 1 | 286
posterior fossa group A ependymoma 1 | 468
tuberculosis 1 | 2,010
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Male tissues 15 | 17,142
Skin and soft tissues 15 | 17,230
Liver and Pancreas 14 | 16,750
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Urinary Tract 14 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Enzyme 14 | 4,145
Transcription Factor 1 | 1,400

GO Function

lyase activity 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutathione-specific gamma-glutamylcyclotransferase 2 CHAC2 Tdark Enzyme -0.36798 2.89 93
Hydroperoxide isomerase ALOXE3 ALOXE3 Tbio Enzyme -1.51120 32.2 118
tRNA-splicing endonuclease subunit Sen2 TSEN2 Tbio Enzyme -1.02188 10.4 140
High mobility group protein B1 HMGB1 Tbio Transcription Factor -3.05199 2190.4 1145
Prostaglandin E synthase 2 PTGES2 Tchem Enzyme -1.65834 34.9 176
Glycine dehydrogenase (decarboxylating), mitochondrial GLDC Tbio Enzyme -1.79392 65.7 131
Gamma-glutamylcyclotransferase GGCT Tbio Enzyme -2.20495 142.5 128
Threonine synthase-like 2 THNSL2 Tbio Enzyme -1.56098 37.5 97
Glutathione-specific gamma-glutamylcyclotransferase 1 CHAC1 Tbio Enzyme -1.29114 18.9 179
Gamma-glutamylaminecyclotransferase GGACT Tbio Enzyme -1.17448 15.0 65