Development Level

Tbio 16 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
increased circulating alkaline... 2 | 122
increased total body fat amoun... 2 | 134
abnormal tooth morphology 1 | 24
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
premature death 1 | 5

Disease

ovarian cancer 18 | 8,520
psoriasis 15 | 6,694
Carcinoma 14 | 11,493
Breast cancer 11 | 3,578
medulloblastoma, large-cell 11 | 6,241
glioblastoma 10 | 5,792
osteosarcoma 10 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
Cancer 8 | 2,499
diabetes mellitus 8 | 1,728
lung cancer 8 | 4,740
Atherosclerosis 7 | 291
ependymoma 7 | 4,679
group 3 medulloblastoma 7 | 4,104
juvenile dermatomyositis 7 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Cardiovascular system disease 6 | 246
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
Autosomal recessive predisposition 5 | 1,442
Cerebrovascular disease 5 | 238
Coronary artery disease 5 | 268
Dementia 5 | 175
Lipid metabolism disorder 5 | 114
Obesity 5 | 678
Rheumatoid arthritis 5 | 1,191
acute quadriplegic myopathy 5 | 1,158
dermatomyositis 5 | 966
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
ulcerative colitis 5 | 1,819
Alzheimer Disease 4 | 83
Alzheimer's disease 4 | 658
Amyloidosis 4 | 67
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Heart disease 4 | 306
Hypercholesterolemia 4 | 44
Hypercholesterolemia, Familial 4 | 23
Hyperlipoproteinemia Type IIa 4 | 11
Hypertensive disease 4 | 292
Kidney cancer 4 | 2,613
Kidney disease 4 | 430
Neurodegenerative disease 4 | 414
Parkinson's disease 4 | 392
Polycystic ovary syndrome 4 | 360
Schizophrenia 4 | 1,160
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
subependymal giant cell astrocytoma 4 | 2,287
Arcus Senilis 3 | 11
Brain disease 3 | 96
Cardiovascular Diseases 3 | 59
Familial hypercholesterolemia - homozygous 3 | 7
Gait abnormality 3 | 135
Hyperglycemia 3 | 137
Hyperlipidemia 3 | 43
Hypertension 3 | 396
Hypertriglyceridemia 3 | 17
Liver cancer 3 | 604
Liver disease 3 | 237
Low density lipoprotein increased 3 | 8
Myocardial Infarction 3 | 151
Osteoporosis 3 | 363
Seizures 3 | 596
Serum cholesterol raised 3 | 22
Steatohepatitis 3 | 44
adult high grade glioma 3 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
progressive supranuclear palsy 3 | 676
Amyotrophic lateral sclerosis 2 | 451
Arcus juvenilis 2 | 5
Cognition Disorders 2 | 32
DOID:2627 2 | 94
Hypothyroidism 2 | 122
Large intestine cancer 2 | 126
Leishmaniasis 2 | 47
Low Vision 2 | 174
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Myopathy 2 | 185
Neuropathy 2 | 261
Osteoarthritis 2 | 184
Pain agnosia 2 | 104
Toxic encephalopathy 2 | 141
Visual Impairment 2 | 174
head and neck cancer and chronic obstructive pulmonary disease 2 | 239

Tissue

Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Skin and soft tissues 22 | 17,230
Blood and immune system 21 | 16,909
Urinary Tract 21 | 16,678
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 2 | 4,145

GO Function

low-density lipoprotein partic... 22 | 22
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
Endoplasmin HSP90B1 Tchem Non-IDG -2.76074 629.2 850
Sorting nexin-17 SNX17 Tbio Non-IDG -1.19414 18.3 101
Ankyrin repeat family A protein 2 ANKRA2 Tbio Non-IDG -0.53092 4.21 117
Apolipoprotein B-100 APOB Tchem Non-IDG -4.00022 10024.1 856
LRP chaperone MESD MESD Tbio Non-IDG -1.40765 27.5 117
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.92862 84.7 130
AP-2 complex subunit alpha-1 AP2A1 Tbio Non-IDG -0.60535 3.75 186
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.79271 621.8 694