Development Level

Tbio 3 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
embryonic lethality prior to t... 1 | 278
pallor 1 | 34
preweaning lethality, complete... 1 | 979

Disease

psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Breast cancer 2 | 3,578
Carcinoma 2 | 11,493
Endometrial cancer 2 | 311
Immune system cancer 2 | 140
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Schizophrenia 2 | 1,160
Unipolar Depression 2 | 250
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abdominal aortic aneurysm 1 | 9
Alzheimer Disease 1 | 83
Amyloidosis 1 | 67
Aortic aneurysm 1 | 38
Atrophoderma vermiculata 1 | 1
Atrophoderma vermiculatum 1 | 1
Auditory auras 1 | 2
Autism Spectrum Disorders 1 | 75
Autism spectrum disorder 1 | 101
Autistic Disorder 1 | 364
Bipolar Disorder 1 | 666
Cardiovascular system disease 1 | 246
Chronic obstructive pulmonary disease 1 | 184
Classical Lissencephaly 1 | 2
Common Migraine 1 | 7
Complex partial seizure with impairment of consciousness 1 | 9
Complex partial seizures 1 | 9
Convex nasal bridge 1 | 57
Coronary artery disease 1 | 268
DOID:2627 1 | 94
Depressive Disorder, Major 1 | 19
Depressive disorder 1 | 409
EPILEPSY, FAMILIAL TEMPORAL LOBE, 7 1 | 1
EPILEPSY, LATERAL TEMPORAL LOBE, AUTOSOMAL DOMINANT 1 | 3
Epilepsy 1 | 792
Epilepsy, Familial Temporal Lobe, 1 1 | 3
Hyperlipoproteinemia Type IV 1 | 3
Hyperlipoproteinemia Type V 1 | 3
Hyperlipoproteinemia type III 1 | 4
Hypertriglyceridemia 1 | 17
Inner ear disease 1 | 1
Keratosis follicularis spinulosa decalvans 1 | 2
Keratosis pilaris decalvans 1 | 3
LISSENCEPHALY SYNDROME, NORMAN-ROBERTS TYPE 1 | 1
Large intestine cancer 1 | 126
Lipid metabolism disorder 1 | 114
Lissencephaly 1 | 69
Lissencephaly 2 1 | 1
Mental Depression 1 | 333
Migraine 1 | 83
Migraine Disorders 1 | 76
Migraine without Aura 1 | 11
Mood Disorders 1 | 184
Multiple Sclerosis 1 | 540
Norman Roberts lissencephaly syndrome 1 | 1
Otosclerosis 1 | 15
Pancreatitis 1 | 123
Partial seizures with secondary generalisation 1 | 4
Pediatric Obesity 1 | 4
Periventricular nodular heterotopia 1 | 30
Prominent nasal bridge 1 | 57
Simple Partial Seizures 1 | 2
Skin cancer 1 | 469
Thick cerebral cortex 1 | 5
Tuberous sclerosis 1 | 19
Vascular disease 1 | 319
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
ductal carcinoma in situ 1 | 1,745
familial hypertriglyceridemia 1 | 4
familial temporal lobe epilepsy 7 1 | 1
fibroadenoma 1 | 559
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung cancer 1 | 4,740
mucosa-associated lymphoid tissue lymphoma 1 | 484
osteosarcoma 1 | 7,950
pancreatic cancer 1 | 2,398
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
primary pancreatic ductal adenocarcinoma 1 | 1,109
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Urinary Tract 2 | 16,678

Target Family

Non-IDG 3 | 12,091

GO Function

lipoprotein particle receptor ... 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Reelin RELN Tbio Non-IDG -2.78255 645.2 121
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
Prolow-density lipoprotein receptor-related protein 1 LRP1 Tbio Non-IDG -2.52012 357.1 711